{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T22:47:39Z","timestamp":1788821259071,"version":"build-2803163510"},"reference-count":126,"publisher":"Baishideng Publishing Group Inc.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJM"],"published-print":{"date-parts":[[2017]]},"DOI":"10.5662\/wjm.v7.i2.37","type":"journal-article","created":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T08:42:02Z","timestamp":1498034522000},"page":"37","source":"Crossref","is-referenced-by-count":27,"title":["Antioxidants in experimental ischemia-reperfusion injury of the testis: Where are we heading towards?"],"prefix":"10.5662","volume":"7","author":[{"given":"George","family":"Vaos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Zavras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S52413"},{"key":"ref2","unstructured":"Sharp VJ, Kieran K, Arlen AM. Testicular torsion: diagnosis, evaluation, and management. Am Fam Physician 2013;88:835-840."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2014.135"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2016.08.012"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2012.05.016"},{"key":"ref6","unstructured":"Skondras I, Lambropoulou M, Tsaroucha A, Gardikis S, Tripsianis G, Simopoulos C, Vaos G. The role of Apigenin in testicular damage in experimental ischemia-reperfusion injury in rats. Hippokratia 2015;19:225-230."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.07.024"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2012.08.002"},{"key":"ref9","unstructured":"Dursun R, Zengin Y, G\u00fcnd\u00fcz E, \u0130\u00e7er M, Durgun HM, Da\u011fgulli M, Kaplan \u0130, Alabal\u0131k U, G\u00fclo\u011flu C. The protective effect of goji berry extract in ischemic reperfusion in testis torsion. Int J Clin Exp Med 2015;8:2727-2733."},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4103\/1008-682X.122202"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(99)90778-9"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2015.47697"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Cuzzocrea S, Riley DP, Caputi AP, Salvemini D. Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia\/reperfusion injury. Pharmacol Rev 2001;53:135-159.","DOI":"10.1016\/S0031-6997(24)01484-4"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-09597-4_9"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/761264"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.108.005132"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.2174\/156800908786241050"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19980106"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/830616"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2009.03.022"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-86502011000400014"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0272.2010.01044.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.218.141"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.4111\/kju.2010.51.11.794"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1055\/s-1999-14034"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0272.2009.01028.x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-004-0436-4"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.06.086"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2004.05.044"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-006-1871-9"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1002\/iub.40"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/0009-3084(87)90053-3"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002482"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-007-0200-9"},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"Chikuma M, Masuda S, Kobayashi T, Nagao M, Sasaki R. Tissue-specific regulation of erythropoietin production in the murine kidney, brain, and uterus. Am J Physiol Endocrinol Metab 2000;279:E1242-E1248.","DOI":"10.1152\/ajpendo.2000.279.6.E1242"},{"key":"ref36","unstructured":"Koksal M, O\u011fuz E, Baba F, Eren MA, Ciftci H, Demir ME, Kurcer Z, Take G, Aral F, Ocak AR. Effects of melatonin on testis histology, oxidative stress and spermatogenesis after experimental testis ischemia-reperfusion in rats. Eur Rev Med Pharmacol Sci 2012;16:582-588."},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0272.2008.00806.x"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1210\/en.2011-1016"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(90)90250-O"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1038\/35025215"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.3109\/00365591003636588"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-013-0569-x"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1159\/000321492"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0b013e328329a449"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2006.01145.x"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1159\/000273476"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-007-0189-2"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-009-2538-0"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2013.04.016"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00553.2011"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-009-0004-8"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2009.02.007"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-394309-5.00006-7"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2010.05.005"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2010.01.003"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2007-8-6-218"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2011.11.002"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2011.11.004"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1111\/j.1549-8719.1999.tb00099.x"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.57.030195.001523"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.109.207381"},{"key":"ref62","doi-asserted-by":"crossref","unstructured":"Granger DN. Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 1988;255:H1269-H1275.","DOI":"10.1152\/ajpheart.1988.255.6.H1269"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1016\/S0928-4680(01)00063-3"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1139\/Y09-101"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/686137"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-776-7_17"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2004.02.132"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-02062-9_7"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-86502009000200008"},{"key":"ref70","doi-asserted-by":"crossref","unstructured":"Akg\u00fcr FM, Kilin\u00e7 K, Aktu\u011f T. Is ipsilateral testis mandatory for the occurrence of contralateral intratesticular biochemical changes indicative of hypoxia after unilateral spermatic cord torsion? Eur Urol 1995;28:143-146.","DOI":"10.1159\/000475039"},{"key":"ref71","doi-asserted-by":"crossref","unstructured":"Becker EJ, Turner TT. Endocrine and exocrine effects of testicular torsion in the prepubertal and adult rat. J Androl 1995;16:342-351.","DOI":"10.1002\/j.1939-4640.1995.tb00539.x"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.1985.tb00817.x"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.1984.tb00781.x"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1989.tb05949.x"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)92056-7"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1078\/0944711041495254"},{"key":"ref77","unstructured":"Nagaraja HS, Anupama BK. Apigenin reduces cyclosporine-A induced changes in lipid hydroperoxides and total antioxidants in Sprague-Dawley rats. J Chin Clin Med 2009;4:26-31."},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.10.007"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1111\/and.12464"},{"key":"ref80","unstructured":"Zager RA, Mahan J, Merola AJ. Effects of mannitol on the postischemic kidney. Biochemical, functional, and morphologic assessments. Lab Invest 1985;53:433-442."},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2016.01.004"},{"key":"ref82","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2011.06.002"},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.1016\/S1734-1140(10)70321-2"},{"key":"ref84","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2006.06.020"},{"key":"ref85","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2012.01.069"},{"key":"ref86","doi-asserted-by":"publisher","DOI":"10.4149\/bll_2014_053"},{"key":"ref87","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-3019(03)00539-1"},{"key":"ref88","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(00)00845-6"},{"key":"ref89","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2013.08.007"},{"key":"ref90","doi-asserted-by":"publisher","DOI":"10.1111\/and.12499"},{"key":"ref91","doi-asserted-by":"publisher","DOI":"10.1002\/biof.552210140"},{"key":"ref92","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-013-1049-8"},{"key":"ref93","doi-asserted-by":"publisher","DOI":"10.1002\/biof.5520240109"},{"key":"ref94","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-012-3168-5"},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1080\/10715760000301121"},{"key":"ref96","unstructured":"Yu G, Liu X, Chen Z, Chen H, Wang L, Wang Z, Qiu T, Weng X. Ozone therapy could attenuate tubulointerstitial injury in adenine-induced CKD rats by mediating Nrf2 and NF-\u03baB. Iran J Basic Med Sci 2016;19:1136-1143."},{"key":"ref97","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2012.06.049"},{"key":"ref98","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2010.12.024"},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2016.06.003"},{"key":"ref100","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.05.034"},{"key":"ref101","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-8206.2004.00279.x"},{"key":"ref102","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2010.02644.x"},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.1590\/S1677-5538.IBJU.2014.01.16"},{"key":"ref104","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.01.029"},{"key":"ref105","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.07.088"},{"key":"ref106","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2008.05.165"},{"key":"ref107","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.09.035"},{"key":"ref108","doi-asserted-by":"publisher","DOI":"10.1100\/2012\/489248"},{"key":"ref109","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2009.07.026"},{"key":"ref110","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-3623(96)00474-0"},{"key":"ref111","doi-asserted-by":"publisher","DOI":"10.1016\/S1734-1140(11)70600-4"},{"key":"ref112","doi-asserted-by":"publisher","DOI":"10.1111\/nure.12044"},{"key":"ref113","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.04899.x"},{"key":"ref114","unstructured":"Kaminska B, Ciereszko R, Kiezun M, Dusza L. In vitro effects of genistein and daidzein on the activity of adrenocortical steroidogenic enzymes in mature female pigs. J Physiol Pharmacol 2013;64:103-108."},{"key":"ref115","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.3689"},{"key":"ref116","unstructured":"Al-Maghrebi M, Renno WM. Genistein alleviates testicular ischemia and reperfusion injury-induced spermatogenic damage and oxidative stress by suppressing abnormal testicular matrix metalloproteinase system via the Notch 2\/Jagged 1\/Hes-1 and caspase-8 pathways. J Physiol Pharmacol 2016;67:129-137."},{"key":"ref117","doi-asserted-by":"publisher","DOI":"10.2174\/156652407782564363"},{"key":"ref118","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.3160"},{"key":"ref119","doi-asserted-by":"publisher","DOI":"10.2174\/1568016043356174"},{"key":"ref120","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/395284"},{"key":"ref121","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2016.09.091"},{"key":"ref122","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2009000700006"},{"key":"ref123","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.04.065"},{"key":"ref124","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2012.08.006"},{"key":"ref125","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2016.06.017"},{"key":"ref126","doi-asserted-by":"publisher","DOI":"10.1111\/andr.12268"}],"container-title":["World Journal of Methodology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/2222-0682\/full\/v7\/i2\/37.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T21:44:22Z","timestamp":1750369462000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/2222-0682\/full\/v7\/i2\/37.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":126,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.5662\/wjm.v7.i2.37","relation":{},"ISSN":["2222-0682"],"issn-type":[{"value":"2222-0682","type":"print"}],"subject":[],"published":{"date-parts":[[2017]]}}}