{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T08:53:35Z","timestamp":1790499215372,"version":"4.1.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,2,15]],"date-time":"2018-02-15T00:00:00Z","timestamp":1518652800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2018,2,15]],"date-time":"2018-02-15T00:00:00Z","timestamp":1518652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Clin Sleep Med"],"published-print":{"date-parts":[[2018,2,15]]},"DOI":"10.5664\/jcsm.6944","type":"journal-article","created":{"date-parts":[[2018,2,14]],"date-time":"2018-02-14T16:33:24Z","timestamp":1518626004000},"page":"245-252","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Nocturnal REM Sleep Without Atonia Is a Diagnostic Biomarker of Pediatric Narcolepsy"],"prefix":"10.1007","volume":"14","author":[{"given":"Saadoun","family":"Bin-Hasan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandar","family":"Videnovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran","family":"Maski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,2,15]]},"reference":[{"issue":"5","key":"1402012_CR1","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.sleep.2014.01.015","volume":"15","author":"MJ Thorpy","year":"2014","unstructured":"Thorpy MJ, Krieger AC. Delayed diagnosis of narcolepsy: characterization and impact. Sleep Med. 2014;15(5):502\u2013507.","journal-title":"Sleep Med"},{"issue":"7","key":"1402012_CR2","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1001\/jamaneurol.2013.1589","volume":"70","author":"O Andlauer","year":"2013","unstructured":"Andlauer O, Moore H, Jouhier L, et al. Nocturnal rapid eye movement sleep latency for identifying patients with narcolepsy\/hypocretin deficiency. JAMA Neurol. 2013;70(7):891\u2013902.","journal-title":"JAMA Neurol"},{"issue":"6","key":"1402012_CR3","first-page":"859","volume":"38","author":"J Reiter","year":"2015","unstructured":"Reiter J, Katz E, Scammell TE, Maski K. Usefulness of a nocturnal SOREMP for diagnosing narcolepsy with cataplexy in a pediatric population. Sleep. 2015;38(6):859\u2013865.","journal-title":"Sleep"},{"issue":"10","key":"1402012_CR4","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.5664\/jcsm.3078","volume":"9","author":"A Khalil","year":"2013","unstructured":"Khalil A, Wright MA, Walker MC, Eriksson SH. Loss of rapid eye movement sleep atonia in patients with REM sleep behavioral disorder, narcolepsy, and isolated loss of REM atonia. J Clin Sleep Med. 2013;9(10):1039\u20131048.","journal-title":"J Clin Sleep Med"},{"issue":"6","key":"1402012_CR5","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1093\/brain\/awx096","volume":"140","author":"E Antelmi","year":"2017","unstructured":"Antelmi E, Pizza F, Vandi S, et al. The spectrum of REM sleep-related episodes in children with type 1 narcolepsy. Brain. 2017;140(6):1669\u20131679.","journal-title":"Brain"},{"issue":"7","key":"1402012_CR6","doi-asserted-by":"crossref","first-page":"675","DOI":"10.5664\/jcsm.2836","volume":"9","author":"LM DelRosso","year":"2013","unstructured":"DelRosso LM, Chesson AL, Hoque R. Characterization of REM sleep without atonia in patients with narcolepsy and idiopathic hypersomnia using AASM scoring manual criteria. J Clin Sleep Med. 2013;9(7):675\u2013680.","journal-title":"J Clin Sleep Med"},{"issue":"8","key":"1402012_CR7","doi-asserted-by":"crossref","first-page":"805","DOI":"10.5664\/jcsm.2926","volume":"9","author":"B Frauscher","year":"2013","unstructured":"Frauscher B, Ehrmann L, Mitterling T, et al. Delayed diagnosis, range of severity, and multiple sleep comorbidities: a clinical and polysomnographic analysis of 100 patients of the innsbruck narcolepsy cohort. J Clin Sleep Med. 2013;9(8):805\u2013812.","journal-title":"J Clin Sleep Med"},{"issue":"5","key":"1402012_CR8","doi-asserted-by":"crossref","first-page":"665","DOI":"10.5664\/jcsm.6576","volume":"13","author":"RB Berry","year":"2017","unstructured":"Berry RB, Brooks R, Gamaldo C, et al. AASM scoring manual updates for 2017 (version 2.4). J Clin Sleep Med. 2017;13(5):665\u2013666.","journal-title":"J Clin Sleep Med"},{"key":"1402012_CR9","volume-title":"International Classification of Sleep Disorders","author":"American Academy of Sleep Medicine","year":"2014","unstructured":"American Academy of Sleep Medicine. International Classification of Sleep Disorders. 3rd ed. Darien, IL: American Academy of Sleep Medicine; 2014.","edition":"3"},{"issue":"Pt 2","key":"1402012_CR10","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1093\/brain\/awp320","volume":"133","author":"S Knudsen","year":"2010","unstructured":"Knudsen S, Gammeltoft S, Jennum PJ. Rapid eye movement sleep behaviour disorder in patients with narcolepsy is associated with hypocretin-1 deficiency. Brain. 2010;133(Pt 2):568\u2013579.","journal-title":"Brain"},{"issue":"25","key":"1402012_CR11","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1056\/NEJMoa1215881","volume":"368","author":"CL Marcus","year":"2013","unstructured":"Marcus CL, Moore RH, Rosen CL, et al. A randomized trial of adenotonsillectomy for childhood sleep apnea. N Engl J Med. 2013;368(25):2366\u20132376.","journal-title":"N Engl J Med"},{"key":"1402012_CR12","volume-title":"The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications","author":"C Iber","year":"2007","unstructured":"Iber C, Ancoli-Israel S, Chesson A, Quan S; for the American Academy of Sleep Medicine. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. 1st ed. Westchester, IL: American Academy of Sleep Medicine; 2007."},{"issue":"3","key":"1402012_CR13","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1365-2869.2011.00958.x","volume":"21","author":"R Ferri","year":"2012","unstructured":"Ferri R, Bruni O, Fulda S, Zucconi M, Plazzi G A quantitative analysis of the submentalis muscle electromyographic amplitude during rapid eye movement sleep across the lifespan. J Sleep Res. 2012;21(3):257\u2013263.","journal-title":"J Sleep Res"},{"issue":"7093","key":"1402012_CR14","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/nature04767","volume":"441","author":"J Lu","year":"2006","unstructured":"Lu J, Sherman D, Devor M, Saper CB A putative flip-flop switch for control of REM sleep. Nature. 2006;441(7093):589\u2013594.","journal-title":"Nature"},{"issue":"1-2","key":"1402012_CR15","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0006-8993(01)02317-4","volume":"901","author":"MC Xi","year":"2001","unstructured":"Xi MC, Morales FR, Chase MH. Effects on sleep and wakefulness of the injection of hypocretin-1 (orexin-A) into the laterodorsal tegmental nucleus of the cat. Brain Res. 2001;901(1-2):259\u2013264.","journal-title":"Brain Res"},{"issue":"8","key":"1402012_CR16","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.sleep.2012.10.006","volume":"14","author":"Y Dauvilliers","year":"2013","unstructured":"Dauvilliers Y, Jennum P, Plazzi G. Rapid eye movement sleep behavior disorder and rapid eye movement sleep without atonia in narcolepsy. Sleep Med. 2013;14(8):775\u2013781.","journal-title":"Sleep Med"},{"issue":"10","key":"1402012_CR17","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1001\/archneur.59.10.1553","volume":"59","author":"E Mignot","year":"2002","unstructured":"Mignot E, Lammers GJ, Ripley B, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol. 2002;59(10):1553\u20131562.","journal-title":"Arch Neurol"},{"issue":"8","key":"1402012_CR18","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1093\/sleep\/32.8.993","volume":"32","author":"TC Thannickal","year":"2009","unstructured":"Thannickal TC, Nienhuis R, Siegel JM. Localized loss of hypocretin (orexin) cells in narcolepsy without cataplexy. Sleep. 2009;32(8):993\u2013998.","journal-title":"Sleep"},{"issue":"5","key":"1402012_CR19","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/jsr.12044","volume":"22","author":"G Luca","year":"2013","unstructured":"Luca G, Haba-Rubio J, Dauvilliers Y, et al. Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study. J Sleep Res. 2013;22(5):482\u2013495.","journal-title":"J Sleep Res"},{"issue":"6","key":"1402012_CR20","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.5665\/sleep.3756","volume":"37","author":"CR Baumann","year":"2014","unstructured":"Baumann CR, Mignot E, Lammers GJ, et al. Challenges in diagnosing narcolepsy without cataplexy: a consensus statement. Sleep. 2014;37(6):1035\u20131042.","journal-title":"Sleep"},{"issue":"3","key":"1402012_CR21","doi-asserted-by":"crossref","first-page":"419","DOI":"10.5664\/jcsm.6494","volume":"13","author":"K Maski","year":"2017","unstructured":"Maski K, Steinhart E, Williams D, et al. Listening to the patient voice in narcolepsy: diagnostic delay, disease burden, and treatment efficacy. J Clin Sleep Med. 2017;13(3):419\u2013425.","journal-title":"J Clin Sleep Med"},{"issue":"1","key":"1402012_CR22","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.sleep.2009.02.009","volume":"11","author":"G Sansa","year":"2010","unstructured":"Sansa G, Iranzo A, Santamaria J. Obstructive sleep apnea in narcolepsy. Sleep Med. 2010;11(1):93\u201395.","journal-title":"Sleep Med"},{"issue":"3","key":"1402012_CR23","first-page":"347","volume":"22","author":"E Mignot","year":"1999","unstructured":"Mignot E, Young T, Lin L, Finn L. Nocturnal sleep and daytime sleepiness in normal subjects with HLA-DQB1*0602. Sleep. 1999; 22(3):347\u2013352.","journal-title":"Sleep"}],"container-title":["Journal of Clinical Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.5664\/jcsm.6944.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.5664\/jcsm.6944\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/jcsm.aasm.org\/ViewAbstract.aspx?pid=31190","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.5664\/jcsm.6944.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T08:20:59Z","timestamp":1770366059000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.5664\/jcsm.6944"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,15]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2,15]]}},"alternative-id":["1402012"],"URL":"https:\/\/doi.org\/10.5664\/jcsm.6944","relation":{},"ISSN":["1550-9389","1550-9397"],"issn-type":[{"value":"1550-9389","type":"print"},{"value":"1550-9397","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,15]]},"assertion":[{"value":"17 August 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 October 2017","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 November 2017","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 February 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}