{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:52:47Z","timestamp":1791420767497,"version":"4.3.3"},"reference-count":94,"publisher":"Oxford University Press (OUP)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12,1]]},"DOI":"10.5665\/sleep.4244","type":"journal-article","created":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T15:46:39Z","timestamp":1417016799000},"page":"1929-1940","source":"Crossref","is-referenced-by-count":127,"title":["Cell Injury and Repair Resulting from Sleep Loss and Sleep Recovery in Laboratory Rats"],"prefix":"10.1093","volume":"37","author":[{"given":"Carol A.","family":"Everson","sequence":"first","affiliation":[{"name":"Department of Neurology, The Medical College of Wisconsin, Milwaukee, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Henchen","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Medical College of Wisconsin, Milwaukee, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aniko","family":"Szabo","sequence":"additional","affiliation":[{"name":"Department of Population Health, The Medical College of Wisconsin, Milwaukee, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Hogg","sequence":"additional","affiliation":[{"name":"Department of Biophysics, The Medical College of Wisconsin, Milwaukee, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,12,1]]},"reference":[{"key":"key\n\t\t\t\t2018112203564511400_B1","year":"2011"},{"key":"key\n\t\t\t\t2018112203564511400_B2","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/j.sleep.2012.08.005","article-title":"Sleep duration versus sleep insufficiency as predictors of cardiometabolic health outcomes","volume":"13","author":"Altman","year":"2012","journal-title":"Sleep Med"},{"key":"key\n\t\t\t\t2018112203564511400_B3","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.jpsychores.2004.02.010","article-title":"Sleep disturbances and chronic disease in older adults: results of the 2003 National Sleep Foundation Sleep in America Survey","volume":"56","author":"Foley","year":"2004","journal-title":"J Psychosom Res"},{"issue":"1","key":"key\n\t\t\t\t2018112203564511400_B4","doi-asserted-by":"crossref","first-page":"e30972","DOI":"10.1371\/journal.pone.0030972","article-title":"Association of sleep duration with chronic diseases in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study","volume":"7","author":"von Ruesten","year":"2012","journal-title":"PLoS ONE"},{"key":"key\n\t\t\t\t2018112203564511400_B5","doi-asserted-by":"crossref","DOI":"10.5962\/bhl.title.6431","article-title":"The Effects of Inanition and Malnutrition Upon Growth and Structure","author":"Jackson","year":"1925"},{"key":"key\n\t\t\t\t2018112203564511400_B6","volume-title":"Fasting and Undernutrition","author":"Morgulis","year":"1923"},{"key":"key\n\t\t\t\t2018112203564511400_B7","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1152\/ajpregu.00565.2004","article-title":"Antioxidant defense responses to sleep loss and sleep recovery","volume":"288","author":"Everson","year":"2005","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"key\n\t\t\t\t2018112203564511400_B8","volume-title":"Free Radicals in Biology and Medicine","author":"Halliwell","year":"1999","edition":"3rd ed"},{"key":"key\n\t\t\t\t2018112203564511400_B9","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1046\/j.1523-1747.2001.01373.x","article-title":"Stress-induced changes in skin barrier function in healthy women","volume":"117","author":"Altemus","year":"2001","journal-title":"J Invest Dermatol"},{"key":"key\n\t\t\t\t2018112203564511400_B10","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1159\/000061563","article-title":"Clinical manifestations of prolonged sleep deprivation","volume-title":"Sleep Science: Integrating Basic Research and Clinical Practice","author":"Everson","year":"1997"},{"key":"key\n\t\t\t\t2018112203564511400_B11","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.bbi.2007.04.003","article-title":"The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults","volume":"21","author":"Frey","year":"2007","journal-title":"Brain Behav Immun"},{"key":"key\n\t\t\t\t2018112203564511400_B12","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1093\/sleep\/30.9.1145","article-title":"Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers","volume":"30","author":"Haack","year":"2007","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2018112203564511400_B13","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.bbi.2003.03.001","article-title":"Sleep-deprived mice show altered cytokine production manifest by perturbations in serum IL-1ra, TNFa, and IL-6 levels","volume":"17","author":"Hu","year":"2003","journal-title":"Brain Behav Immun"},{"key":"key\n\t\t\t\t2018112203564511400_B14","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.jacc.2003.07.050","article-title":"Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk","volume":"43","author":"Meier-Ewert","year":"2004","journal-title":"JACC"},{"key":"key\n\t\t\t\t2018112203564511400_B15","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1096\/fasebj.3.8.2785942","article-title":"Effects of sleep deprivation on human immune functions","volume":"3","author":"Moldofsky","year":"1989","journal-title":"FASEB J"},{"key":"key\n\t\t\t\t2018112203564511400_B16","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1067\/mai.2001.112270","article-title":"Soluble TNF-alpha receptor 1 and IL-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight","volume":"107","author":"Shearer","year":"2001","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"key\n\t\t\t\t2018112203564511400_B17","doi-asserted-by":"crossref","first-page":"e4589","DOI":"10.1371\/journal.pone.0004589","article-title":"Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP","volume":"4","author":"van Leeuwen","year":"2009","journal-title":"PLoS ONE"},{"key":"key\n\t\t\t\t2018112203564511400_B18","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1210\/jc.2003-031562","article-title":"Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines","volume":"89","author":"Vgontzas","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2018112203564511400_B19","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1469-7580.2008.00860.x","article-title":"Sleep deprivation predisposes liver to oxidative stress and phospholipid damage: a quantitative molecular imaging study","volume":"212","author":"Chang","year":"2008","journal-title":"J Anat"},{"key":"key\n\t\t\t\t2018112203564511400_B20","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1111\/j.1471-4159.2006.04058.x","article-title":"Changes in brain gene expression after long-term sleep deprivation","volume":"98","author":"Cirelli","year":"2006","journal-title":"J Neurochem"},{"key":"key\n\t\t\t\t2018112203564511400_B21","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1152\/ajpregu.90623.2008","article-title":"Phagocyte migration and cellular stress induced in liver, lung, and intestine during sleep loss and sleep recovery","volume":"295","author":"Everson","year":"2008","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"key\n\t\t\t\t2018112203564511400_B22","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1080\/00365520410004523","article-title":"Over-expression of inducible heat shock protein 70 in the gastric mucosa of partially sleep-deprived rats","volume":"39","author":"Guo","year":"2004","journal-title":"Scand J Gastroenterol"},{"key":"key\n\t\t\t\t2018112203564511400_B23","doi-asserted-by":"crossref","first-page":"6539","DOI":"10.1523\/JNEUROSCI.5685-07.2008","article-title":"Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling","volume":"28","author":"Naidoo","year":"2008","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t2018112203564511400_B24","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0306-4522(02)00695-4","article-title":"Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep","volume":"116","author":"Terao","year":"2003","journal-title":"Neuroscience"},{"key":"key\n\t\t\t\t2018112203564511400_B25","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/sji.12029","article-title":"Sleep deprivation alters gene expression and antioxidant enzyme activity in mice splenocytes","volume":"77","author":"Lungato","year":"2013","journal-title":"Scand J Immunol"},{"key":"key\n\t\t\t\t2018112203564511400_B26","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1097\/00001756-200208070-00007","article-title":"Sleep deprivation decreases superoxide dismutase activity in rat hippocampus and brainstem","volume":"13","author":"Ramanathan","year":"2002","journal-title":"Neuroreport"},{"key":"key\n\t\t\t\t2018112203564511400_B27","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1172\/JCI117184","article-title":"Leukocytosis and natural killer cell function parallel neurobehavioral fatigue induced by 64 hours of sleep deprivation","volume":"93","author":"Dinges","year":"1994","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t2018112203564511400_B28","volume-title":"Sleep and Wakefulness","author":"Kleitman","year":"1963"},{"key":"key\n\t\t\t\t2018112203564511400_B29","first-page":"165","article-title":"Metabolic reflection of sleep deprivation","volume":"11","author":"Kuhn","year":"1969","journal-title":"Act Nerv Super (Praha)"},{"key":"key\n\t\t\t\t2018112203564511400_B30","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.pnpbp.2009.02.014","article-title":"Distinct effects of acute and chronic sleep loss on DNA damage in rats","volume":"33","author":"Andersen","year":"2009","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"key\n\t\t\t\t2018112203564511400_B31","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0091-3057(74)90018-5","article-title":"The flower pot technique of rapid eye movement (REM) sleep deprivation","volume":"2","author":"Mendelson","year":"1974","journal-title":"Pharmacol Biochem Behav"},{"key":"key\n\t\t\t\t2018112203564511400_B32","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0031-9384(99)00181-X","article-title":"Social stability attenuates the stress in the modified multiple platform method for paradoxical sleep deprivaiton in the rat","volume":"68","author":"Suchecki","year":"2000","journal-title":"Physiol Behav"},{"key":"key\n\t\t\t\t2018112203564511400_B33","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1152\/ajpregu.00021.2005","article-title":"Clinical assessment of blood leukocytes, serum cytokines, and serum immunoglobulins as responses to sleep deprivation in laboratory rats","volume":"289","author":"Everson","year":"2005","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"key\n\t\t\t\t2018112203564511400_B34","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1152\/ajpregu.1993.265.5.R1148","article-title":"Sustained sleep deprivation impairs host defense","volume":"265","author":"Everson","year":"1993","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"key\n\t\t\t\t2018112203564511400_B35","first-page":"190","article-title":"Pathology in sleep deprived rats is not reflected in histologic abnormalities (Abstract)","volume":"13","author":"Gilliland","year":"1984","journal-title":"Sleep Res"},{"key":"key\n\t\t\t\t2018112203564511400_B36","article-title":"Committee for the Update of the Guide for the Care and Use of Laboratory Animals. Guide for the Care and Use of Laboratory Animals","author":"National Research Council of the National Academies","year":"2011","edition":"8th ed"},{"key":"key\n\t\t\t\t2018112203564511400_B37","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/sleep\/12.1.5","article-title":"Sleep deprivation in the rat: II. Methodology","volume":"12","author":"Bergmann","year":"1989","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2018112203564511400_B38","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1177\/07430402017003006","article-title":"Circadian clock resetting by sleep deprivation without exercise in Syrian hamsters: dark pulses revisited","volume":"17","author":"Mistlberger","year":"2002","journal-title":"J Biol Rhythms"},{"key":"key\n\t\t\t\t2018112203564511400_B39","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1093\/sleep\/15.6.537","article-title":"Sleep deprivation in the rat: XVI. Effects in a light-dark cycle","volume":"15","author":"Tsai","year":"1992","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2018112203564511400_B40","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1152\/japplphysiol.01173.2001","article-title":"Ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality","volume":"92","author":"Romanovsky","year":"2002","journal-title":"J Appl Physiol"},{"key":"key\n\t\t\t\t2018112203564511400_B41","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1152\/ajpregu.1993.264.2.R376","article-title":"Nutritional and metabolic adaptations to prolonged sleep deprivation in the rat","volume":"264","author":"Everson","year":"1993","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"key\n\t\t\t\t2018112203564511400_B42","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/sleep\/12.1.13","article-title":"Sleep deprivation in the rat. III. Total sleep deprivation","volume":"12","author":"Everson","year":"1989","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2018112203564511400_B43","doi-asserted-by":"crossref","first-page":"6769","DOI":"10.1523\/JNEUROSCI.14-11-06769.1994","article-title":"Effects of prolonged sleep deprivation on local rates of cerebral energy metabolism in freely moving rats","volume":"14","author":"Everson","year":"1994","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t2018112203564511400_B44","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1152\/ajpregu.00230.2009","article-title":"Recurrent restriction of sleep and inadequate recuperation induce both adaptive changes and pathological outcomes","volume":"297","author":"Everson","year":"2009","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"key\n\t\t\t\t2018112203564511400_B45","first-page":"60","article-title":"Sleep deprivation in the rat: IX. Recovery","volume":"12","author":"Everson","year":"1989","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2018112203564511400_B46","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/sleep\/22.1.11","article-title":"Effects of method, duration, and sleep stage on rebounds from sleep deprivation in the rat","volume":"22","author":"Rechtschaffen","year":"1999","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2018112203564511400_B47","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/nprot.2006.375","article-title":"Quantification of F2-isoprostanes as a biomarker of oxidative stress","volume":"2","author":"Milne","year":"2007","journal-title":"Nat Protoc"},{"key":"key\n\t\t\t\t2018112203564511400_B48","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal Biochem"},{"key":"key\n\t\t\t\t2018112203564511400_B49","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/B978-0-12-091302-2.50032-3","article-title":"Catalase","volume-title":"Methods of Enzymatic Analysis","author":"Aebi","year":"1974"},{"key":"key\n\t\t\t\t2018112203564511400_B50","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.1016\/S0024-3205(03)00671-4","article-title":"Cardioprotective effect of the alcoholic extract of Terminalia arjuna bark in an in vivo model of myocardial ischemic reperfusion injury","volume":"73","author":"Karthikeyan","year":"2003","journal-title":"Life Sci"},{"key":"key\n\t\t\t\t2018112203564511400_B51","doi-asserted-by":"crossref","first-page":"7911","DOI":"10.1073\/pnas.93.15.7911","article-title":"Induction of intestinal epithelial proliferation by glucagon-like peptide 2","volume":"93","author":"Drucker","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t2018112203564511400_B52","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1001\/archsurg.134.3.287","article-title":"Enteral nutrition prevents bacterial translocation but does not improve survival during acute pancreatitis","author":"Kotani","year":"1999","journal-title":"Arch Surg"},{"key":"key\n\t\t\t\t2018112203564511400_B53","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/path.1183","article-title":"Protection of the Peyer's patch-associated crypt and villus epithelium against methotrexate-induced damage is based on its distinct regulation of proliferation","volume":"198","author":"Renes","year":"2002","journal-title":"J Pathol"},{"key":"key\n\t\t\t\t2018112203564511400_B54","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1136\/gut.21.6.486","article-title":"Response of the rat small-intestine epithelium to methotrexate","volume":"21","author":"Taminiau","year":"1980","journal-title":"Gut"},{"key":"key\n\t\t\t\t2018112203564511400_B55","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0304-3835(94)90297-6","article-title":"Cell proliferation induced by laxatives and related compounds in the rat intestine","volume":"83","author":"Toyoda","year":"1994","journal-title":"Cancer Lett"},{"key":"key\n\t\t\t\t2018112203564511400_B56","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/(SICI)1097-4652(200003)182:3<311::AID-JCP1>3.0.CO;2-9","article-title":"The Ki-67 protein: from the known and the unknown","volume":"182","author":"Scholzen","year":"2000","journal-title":"J Cell Physiol"},{"key":"key\n\t\t\t\t2018112203564511400_B57","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/emboj.2008.15","article-title":"DNA-damage repair; the good, the bad, and the ugly","volume":"27","author":"Hakem","year":"2008","journal-title":"EMBO J"},{"key":"key\n\t\t\t\t2018112203564511400_B58","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/S0891-5849(02)00808-0","article-title":"Effect of diet on cancer development: is oxidative DNA damage a biomarker?","volume":"32","author":"Halliwell","year":"2002","journal-title":"Free Radic Biol Med"},{"key":"key\n\t\t\t\t2018112203564511400_B59","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1080\/10590500902885684","article-title":"8-hydroxy-2' -deoxyguanosine (8-OHdG): a critical biomarker of oxidative stress and carcinogenesis","volume":"27","author":"Valavanidis","year":"2009","journal-title":"J Environ Sci Health Part C Environ Carcinog Ecotoxicol Rev"},{"key":"key\n\t\t\t\t2018112203564511400_B60","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/sj.cdd.4401908","article-title":"Dissecting p53-dependent apoptosis","volume":"13","author":"Chipuk","year":"2006","journal-title":"Cell Death Differ"},{"key":"key\n\t\t\t\t2018112203564511400_B61","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/BF00207507","article-title":"Cancer risk and oxidative DNA damage in man","volume":"74","author":"Loft","year":"1996","journal-title":"J Mol Med"},{"key":"key\n\t\t\t\t2018112203564511400_B62","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0304-3835(99)00424-3","article-title":"Increased formation of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, in human breast cancer tissue and its relationship to GSTP1 and COMT genotypes","volume":"151","author":"Matsui","year":"2000","journal-title":"Cancer Lett"},{"key":"key\n\t\t\t\t2018112203564511400_B63","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1006\/enrs.2000.4072","article-title":"Early oxidative DNA damages and late development of lung cancer in diesel exhaust-exposed rats","volume":"84","author":"Iwai","year":"2000","journal-title":"Environ Res"},{"key":"key\n\t\t\t\t2018112203564511400_B64","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1136\/ard.52.9.659","article-title":"Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases","volume":"52","author":"Bashir","year":"1993","journal-title":"Ann Rheum Dis"},{"key":"key\n\t\t\t\t2018112203564511400_B65","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.bcp.2011.06.025","article-title":"Role of DNA damage in atherosclerosis--bystander or participant?","volume":"82","author":"Gray","year":"2011","journal-title":"Biochem Pharmacol"},{"key":"key\n\t\t\t\t2018112203564511400_B66","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.cardiores.2006.03.002","article-title":"DNA damage and repair in atherosclerosis","volume":"71","author":"Mahmoudi","year":"2006","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t2018112203564511400_B67","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1161\/CIRCRESAHA.111.261388","article-title":"Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence","volume":"111","author":"Wang","year":"2012","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t2018112203564511400_B68","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1139\/cjpp-2012-0251","article-title":"Oxidative-stress-induced epigenetic changes in chronic diabetic complications","volume":"91","author":"Feng","year":"2013","journal-title":"Can J Physiol Pharmacol"},{"key":"key\n\t\t\t\t2018112203564511400_B69","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.diabres.2003.09.015","article-title":"Prevention of type 1 diabetes: from the view point of beta cell damage","volume":"66","author":"Kawasaki","year":"2004","journal-title":"Diabetes Res Clin Pract"},{"key":"key\n\t\t\t\t2018112203564511400_B70","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.3109\/10715762.2012.717692","article-title":"Oxidative stress in ulcerative colitis: an old concept but a new concern","volume":"46","author":"Jena","year":"2012","journal-title":"Free Radic Res"},{"key":"key\n\t\t\t\t2018112203564511400_B71","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/j.1440-1827.2012.02807.x","article-title":"Development of ulcerative colitis and its associated colorectal neoplasia as a model of the organ-specific chronic inflammation-carcinoma sequence","volume":"62","author":"Okayasu","year":"2012","journal-title":"Pathol Int"},{"key":"key\n\t\t\t\t2018112203564511400_B72","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.canlet.2012.02.001","article-title":"Pathways for repairing and tolerating the spectrum of oxidative DNA lesions","volume":"327","author":"Berquist","year":"2012","journal-title":"Cancer Lett"},{"key":"key\n\t\t\t\t2018112203564511400_B73","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1006\/cbir.1996.0018","article-title":"Epithelial cell migration in the intestine","volume":"20","author":"Heath","year":"1996","journal-title":"Cell Biol Int"},{"key":"key\n\t\t\t\t2018112203564511400_B74","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/00005176-198302010-00004","article-title":"The role of cell renewal in the ontogeny of the intestine. I. Cell proliferation patterns in adult, fetal, and neonatal intestine","volume":"2","author":"Klein","year":"1983","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"key\n\t\t\t\t2018112203564511400_B75","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1136\/gut.2.2.110","article-title":"The turnover and shedding of epithelial cells. I. The turnover in the gastro-intestinal tract","author":"Creamer","year":"1961","journal-title":"Gut"},{"key":"key\n\t\t\t\t2018112203564511400_B76","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/B978-1-4160-6189-2.00002-0","article-title":"Mucosal immunity","volume-title":"Sleisenger and Fordtran's Gastrointestinal and Liver Disease","author":"Dotan","year":"2010","edition":"9th ed"},{"key":"key\n\t\t\t\t2018112203564511400_B77","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1113\/jphysiol.1990.sp018347","article-title":"Rat splanchnic net oxygen consumption, energy implications","volume":"431","author":"Casado","year":"1990","journal-title":"J Physiol (Lond)"},{"key":"key\n\t\t\t\t2018112203564511400_B78","first-page":"23","article-title":"Contribution of visceral organs to animal energy expenditures","volume":"66","author":"Ferrell","year":"1988","journal-title":"J Anim Sci"},{"key":"key\n\t\t\t\t2018112203564511400_B79","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/carcin\/24.3.353","article-title":"Oxidative stress and ulcerative colitis-associated carcinogenesis: studies in humans and animal models","volume":"24","author":"Seril","year":"2003","journal-title":"Carcinogenesis"},{"key":"key\n\t\t\t\t2018112203564511400_B80","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/wsbm.1176","article-title":"Gut stem cells in tissue renewal and disease: methods, markers, and myths","volume":"4","author":"Rizk","year":"2012","journal-title":"Wiley Interdiscip Rev Syst Biol Med"},{"key":"key\n\t\t\t\t2018112203564511400_B81","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/10715760000300671","article-title":"Measurement of plasma F2-isoprostanes as an index of lipid peroxidation does not appear to be confounded by diet","volume":"33","author":"Gopaul","year":"2000","journal-title":"Free Radic Res"},{"key":"key\n\t\t\t\t2018112203564511400_B82","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0891-5849(99)00264-6","article-title":"Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo","volume":"28","author":"Roberts","year":"2000","journal-title":"Free Radic Biol Med"},{"key":"key\n\t\t\t\t2018112203564511400_B83","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1152\/physrev.00047.2006","article-title":"Life and death: metabolic rate, membrane composition, and life span of animals","volume":"87","author":"Hulbert","year":"2007","journal-title":"Physiol Rev"},{"key":"key\n\t\t\t\t2018112203564511400_B84","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1089\/ars.2006.8.582","article-title":"Is the mitochondrial free radical theory of aging intact?","volume":"8","author":"Sanz","year":"2006","journal-title":"Antioxid Redox Signal"},{"key":"key\n\t\t\t\t2018112203564511400_B85","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1152\/ajpendo.00553.2003","article-title":"Reductions in circulating anabolic hormones induced by sustained sleep deprivation in rats","volume":"286","author":"Everson","year":"2004","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"key\n\t\t\t\t2018112203564511400_B86","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1152\/ajpendo.00558.2001","article-title":"Hypothalamic thyrotropin-releasing hormone mRNA responses to hypothyroxinemia induced by sleep deprivation","volume":"283","author":"Everson","year":"2002","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"key\n\t\t\t\t2018112203564511400_B87","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1210\/endo.136.4.7895653","article-title":"Pituitary and peripheral thyroid hormone responses to thyrotropin-releasing hormone during sustained sleep deprivation in freely moving rats","volume":"136","author":"Everson","year":"1995","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t2018112203564511400_B88","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.pnpbp.2012.02.011","article-title":"Oxidative stress in patients with primary insomnia","volume":"37","author":"Gulec","year":"2012","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"key\n\t\t\t\t2018112203564511400_B89","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/sleep\/27.1.27","article-title":"Sleep deprivation and cellular responses to oxidative stress","volume":"27","author":"Gopalakrishnan","year":"2004","journal-title":"Sleep"},{"issue":"5","key":"key\n\t\t\t\t2018112203564511400_B90","doi-asserted-by":"crossref","first-page":"e37150","DOI":"10.1371\/journal.pone.0037150","article-title":"Circadian desynchrony promotes metabolic disruption in a mouse model of shiftwork","volume":"7","author":"Barclay","year":"2012","journal-title":"PLoS ONE"},{"key":"key\n\t\t\t\t2018112203564511400_B91","doi-asserted-by":"crossref","first-page":"E1132","DOI":"10.1073\/pnas.1217154110","article-title":"Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome","volume":"110","author":"Moller-Levet","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t2018112203564511400_B92","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/S0002-9149(77)80191-4","article-title":"Sleep disturbances after open heart surgery","volume":"39","author":"Orr","year":"1977","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t2018112203564511400_B93","article-title":"Scientific rationale for the \u201cAll Hands Awake\u201d 24-hour watchstanding schedule","author":"Soutiere","year":"2013"},{"key":"key\n\t\t\t\t2018112203564511400_B94","doi-asserted-by":"crossref","first-page":"727","DOI":"10.5665\/sleep.1846","article-title":"Boards of Directors of the American Academy of Sleep Medicine and the Sleep Research Society. Sleep: a health imperative","volume":"35","author":"Luyster","year":"2012","journal-title":"Sleep"}],"container-title":["Sleep"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/sleep\/article-pdf\/37\/12\/1929\/26669191\/aasm.37.12.1929.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,30]],"date-time":"2023-07-30T04:46:30Z","timestamp":1690692390000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/sleep\/article\/37\/12\/1929\/2416803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,1]]},"references-count":94,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2014,12,1]]},"published-print":{"date-parts":[[2014,12,1]]}},"URL":"https:\/\/doi.org\/10.5665\/sleep.4244","relation":{},"ISSN":["0161-8105","1550-9109"],"issn-type":[{"value":"0161-8105","type":"print"},{"value":"1550-9109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2014,12]]},"published":{"date-parts":[[2014,12,1]]}}}