{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T06:16:12Z","timestamp":1674627372166},"reference-count":0,"publisher":"STEMM Global Scientific Society","issue":"S2","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["inSTEMM"],"abstract":"<jats:p>The Covid-19 pandemic brought the need to use social masks to prevent the spread of the SARS-CoV-2 virus. However, no reliable and fast method were yet established to detect viral particles and to improve the protective ability of social masks.&#x0D;\nThrough color changes, colorimetric biosensors can be used as a rapid and easily approach to detect virus. Gold nanoparticles (AuNP) are known to have excellent optical properties and huge research potential.&#x0D;\nThe new SARS-CoV-2 has the ability of entering human body cells, namely through a second pathway of entry \u2013 the sialic acid (SA) receptor.&#x0D;\nIn order to respond to the emergency and to contribute to the diminishing of the spread of SAR-CoV-2, we developed a colorimetric biosensor based on the functionalization AuNP by sialic acid (SA) (SA-AuNP), as a new and effective textile coating layer, to provide a direct indication of the protective capacity of social masks.&#x0D;\nTo do that, AuNPs (10 nm) were functionalized with SA (SA-AuNP), in three different concentrations (50-50, 30-70 and 20-80, respectively) to select the optimal concentration for respiratory virus detection. Fourier-transform infrared spectroscopy (FTIR) and Scanning Electron Microscope with a Transmission Detector (STEM) analyses confirmed SA-AuNPs binding. FTIR results showed a well-established bond, through matches of peaks of SA-AuNPs. Bindings between the compounds were more evident in 50-50 concentration of SA-AuNP. In the 30-70 SA-AuNP the STEM images show some superposition of the nanoparticles and not so evident binding, as in the 20-80 concentration. Still, between these last two concentrations, the 30-70 is the one that shows the best results since it is visible some circular points larger than the others. To achieve the goal, the concentrations 30-70 and 50-50 of SA-AuNP were impregnated (Textile Foulard) in two substrates of different compositions, a cellulosic and a synthetic one. However, in this technique there are many parameters, such as drying time and temperature, which were varied to understand which the best procedure was to obtain the biosensor.<\/jats:p>","DOI":"10.56725\/instemm.v1is2.13","type":"journal-article","created":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T16:40:43Z","timestamp":1674578443000},"source":"Crossref","is-referenced-by-count":0,"title":["Development of a sustainable biosensor to detect respiratory infectious diseases"],"prefix":"10.56725","volume":"1","author":[{"given":"Monica","family":"Vieira","sequence":"first","affiliation":[]},{"given":"Ana Margarida","family":"Nascimento","sequence":"additional","affiliation":[]},{"given":"Cristina","family":"Abreu","sequence":"additional","affiliation":[]},{"given":"B\u00e1rbara","family":"Leite","sequence":"additional","affiliation":[]},{"given":"Mariana","family":"Silva","sequence":"additional","affiliation":[]},{"given":"Simon","family":"Rouly","sequence":"additional","affiliation":[]},{"given":"Ricardo","family":"Ferraz","sequence":"additional","affiliation":[]},{"given":"Elsa","family":"Parente","sequence":"additional","affiliation":[]},{"given":"Miguel","family":"Costa","sequence":"additional","affiliation":[]},{"given":"Cristina","family":"Prud\u00eancio","sequence":"additional","affiliation":[]}],"member":"36010","published-online":{"date-parts":[[2022,12,1]]},"container-title":["inSTEMM Journal"],"original-title":[],"link":[{"URL":"https:\/\/journal.stemm.global\/index.php\/instemm\/article\/download\/13\/7","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journal.stemm.global\/index.php\/instemm\/article\/download\/13\/7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T16:40:43Z","timestamp":1674578443000},"score":1,"resource":{"primary":{"URL":"https:\/\/journal.stemm.global\/index.php\/instemm\/article\/view\/13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":0,"journal-issue":{"issue":"S2","published-online":{"date-parts":[[2023,1,3]]}},"URL":"https:\/\/doi.org\/10.56725\/instemm.v1is2.13","relation":{},"ISSN":["2753-6939"],"issn-type":[{"value":"2753-6939","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,1]]}}}