{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T13:49:09Z","timestamp":1747230549708,"version":"3.40.5"},"reference-count":25,"publisher":"Digital Journal of Opthalmology","license":[{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digit J Ophthalmol"],"abstract":"<jats:p>Surgically induced scleral necrosis (SISN) is an uncommon complication of ocular procedures. Cosmetic eye-whitening surgery involves conjunctival and Tenon\u2019s capsule dissection, cautery, and mitomycin C application. We report the case of a 36-year-old white woman referred to our clinic for severe pain, scleral inflammation, and necrosis in both eyes 9 years after I-BRITE, an elective eye-whitening procedure. An extensive workup yielded negative results. The patient improved with aggressive lubrication and topical and high-dose systemic prednisone (60 mg), with recurrence upon steroid tapering. Concomitant weekly methotrexate was added, resulting in inflammatory control and allowing discontinuance of topical and oral steroids.<\/jats:p>","DOI":"10.5693\/djo.02.2023.04.005","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T06:10:17Z","timestamp":1694499017000},"source":"Crossref","is-referenced-by-count":0,"title":["CASE REPORTS: Delayed presentation of surgically induced scleral necrosis after I-BRITE procedure treated with immunosuppressive therapy"],"prefix":"10.5693","author":[{"given":"Nadim S.","family":"Azar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7022-2395","authenticated-orcid":false,"given":"Raul E.","family":"Ruiz-Lozano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5237-240X","authenticated-orcid":false,"given":"Manuel E.","family":"Quiroga-Garza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8695-2541","authenticated-orcid":false,"given":"Matias","family":"Soifer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazem M.","family":"Mousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seitaro","family":"Komai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2415-0690","authenticated-orcid":false,"given":"David L.","family":"Leverenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor L.","family":"Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3822","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"key":"3256","doi-asserted-by":"crossref","unstructured":"Lee S, Go J, Rhiu S, et al. 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