{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T02:02:31Z","timestamp":1792202551294,"version":"4.4.0"},"reference-count":89,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T00:00:00Z","timestamp":1531699200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Journal of Australia"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.5694\/mja18.00241","type":"journal-article","created":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T02:14:17Z","timestamp":1531361657000},"page":"86-91","source":"Crossref","is-referenced-by-count":214,"title":["Chronic idiopathic constipation in adults: epidemiology, pathophysiology, diagnosis and clinical management"],"prefix":"10.5694","volume":"209","author":[{"given":"Christopher J","family":"Black","sequence":"first","affiliation":[{"name":"Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C","family":"Ford","sequence":"additional","affiliation":[{"name":"Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,16]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.08.045"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e318231fc64"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.031"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365529709011203"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.39.1.109"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.612"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01537263"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.5"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12852"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.200"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.164"},{"key":"e_1_2_12_13_1","first-page":"919","article-title":"Epidemiology and management of chronic constipation in elderly patients","volume":"10","author":"Vazquez Roque M","year":"2015","journal-title":"Clin Interv Aging"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12573"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.49.1.66"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.11.2.91"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm14092"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2015.00487"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13375"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00021.2017"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.43.2.294"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1594"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050640616663439"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.95"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520802321212"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2014.20.1.31"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.10.005"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.73"},{"key":"e_1_2_12_29_1","first-page":"53","article-title":"Stool patterns of Malaysian adults with functional constipation: association with diet and physical activity","volume":"19","author":"Mazlyn MM","year":"2013","journal-title":"Malays J Nutr"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i34.5362"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.00326.x"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-301181"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000135929.78074.8c"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5337"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01203.x"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12502"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.29.9.1173"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2010.01597.x"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02088064"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.4.496"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-003-0577-x"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.52"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2016.01.006"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12158"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-008-0226-x"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181fd2356"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.01832.x"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2015.153"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2010.06.031"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13125"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.10.10.842"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13269"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11938-016-0108-9"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13107"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.16.3.209"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.35.12.1747"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04602.x"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13662"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.114.089151"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.202"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.40885.x"},{"key":"e_1_2_12_62_1","first-page":"727","article-title":"Water supplementation enhances the effect of high\u2010fiber diet on stool frequency and laxative consumption in adult patients with functional constipation","volume":"45","author":"Anti M","year":"1998","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-199110000-00010"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.480"},{"key":"e_1_2_12_65_1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.cyto.2017.12.016","article-title":"Low\u2010to\u2010moderate intensity aerobic exercise training modulates irritable bowel syndrome through antioxidative and inflammatory mechanisms in women: results of a randomized controlled trial","volume":"102","author":"Hajizadeh Maleki B","year":"2017","journal-title":"Cytokine"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.227132"},{"key":"e_1_2_12_67_1","first-page":"CD007570","article-title":"Lactulose versus polyethylene glycol for chronic constipation","volume":"7","author":"Lee\u2010Robichaud H","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12278"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2011.03.026"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.41"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2016-311835"},{"key":"e_1_2_12_72_1","unstructured":"Mueller\u2010LissnerSA WaldA.Constipation in adults.BMJ Clin Evid2010;0413."},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200305000-00004"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2016.01.015"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-017-4680-1"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1010863"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756283X17734697"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2016.611"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-016-4147-9"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04456.x"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2006.00865.x"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756283X14528269"},{"key":"e_1_2_12_83_1","first-page":"1021","article-title":"Biofeedback treatment of constipation: a comparison of two methods","volume":"89","author":"Bleijenberg G","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.12.023"},{"key":"e_1_2_12_85_1","first-page":"CD008486","article-title":"Biofeedback for treatment of chronic idiopathic constipation in adults","volume":"3","author":"Woodward S","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_86_1","first-page":"CD002115","article-title":"Management of faecal incontinence and constipation in adults with central neurological diseases","volume":"12","author":"Coggrave M","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365520903583855"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-017-1635-7"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13775"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gassur.2006.09.006"}],"container-title":["Medical Journal of Australia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.5694%2Fmja18.00241","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.5694\/mja18.00241","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.5694\/mja18.00241","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.5694\/mja18.00241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T09:19:12Z","timestamp":1626945552000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.5694\/mja18.00241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":89,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,7,16]]},"published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.5694\/mja18.00241"],"URL":"https:\/\/doi.org\/10.5694\/mja18.00241","archive":["Portico"],"relation":{},"ISSN":["0025-729X","1326-5377"],"issn-type":[{"value":"0025-729X","type":"print"},{"value":"1326-5377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7]]}}}