{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:48:00Z","timestamp":1788281280191,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003921","name":"Department of Health, Australian Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003921","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Journal of Australia"],"published-print":{"date-parts":[[2023,6,5]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n To examine the association between inter\u2010hospital transfer and in\u2010hospital mortality among people with coronavirus disease 2019 (COVID\u201019) admitted to intensive care units (ICUs) in Australia.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Retrospective cohort study; analysis of data collected for the Short Period Incidence Study of Severe Acute Respiratory Illness (SPRINT\u2010SARI) Australia study.<\/jats:p>\n <\/jats:sec>\n \n Setting, participants<\/jats:title>\n People with COVID\u201019 admitted to 63 ICUs, 1 January 2020 \u2013 1 April 2022.<\/jats:p>\n <\/jats:sec>\n \n Main outcome measures<\/jats:title>\n Primary outcome: in\u2010hospital mortality; secondary outcomes: ICU and hospital lengths of stay and frequency of selected complications.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of 5207 people with records in the SPRINT\u2010SARI Australia database at 1 April 2022, 328 (6.3%) had been transferred between hospitals, 305 (93%) during the third pandemic wave. Compared with patients not transferred, their median age was lower (53 years; interquartile range [IQR], 45\u201361 years\n v<\/jats:italic>\n 60 years; IQR, 46\u201370 years), their median body mass index higher (32.5 [IQR, 27.2\u201339.0] kg\/m\n 2<\/jats:sup>\n v<\/jats:italic>\n 30.1 [IQR, 25.7\u201335.7] kg\/m\n 2<\/jats:sup>\n ), and fewer had received a COVID\u201019 vaccine (22%\n v<\/jats:italic>\n 44.9%); their median APACHE II scores were similar (14.0; IQR, 12.0\u201318.0\n v<\/jats:italic>\n 14.0; IQR, 10.0\u201319.0). Bacterial pneumonia (64.7%\n v<\/jats:italic>\n 29.0%) and bacteraemia (27%\n v<\/jats:italic>\n 8%) were more frequent in transferred patients, as was the need for more intensive ICU interventions, including invasive mechanical ventilation (71.2%\n v<\/jats:italic>\n 38.1%) and extra\u2010corporeal membrane oxygenation (26%\n v<\/jats:italic>\n 1.7%). Crude ICU (19%\n v<\/jats:italic>\n 14.9%) and in\u2010hospital mortality (19%\n v<\/jats:italic>\n 18.4%) were similar for patients who were or were not transferred; median lengths of ICU (20.0 [IQR, 11.2\u201340.3] days\n v<\/jats:italic>\n 4.6 [IQR, 2.1\u201310.1] days) and hospital stay (29.7 [IQR, 18.1\u201349.6] days\n v<\/jats:italic>\n 12.3 [IQR, 7.3\u201321.0] days) were longer for transferred patients. In the multivariable regression analysis, in\u2010hospital mortality risk was lower for transferred patients (risk difference [RD], \u20135.0 percentage points; 95% confidence interval [CI] \u201310 to \u20130.03 percentage points), but not in the propensity score\u2010adjusted analysis (RD, \u20133.4 [95% CI, \u20138.9 to 2.1] percentage points).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Among people with COVID\u201019 admitted to ICUs, patients transferred from another hospital required more intense interventions and remained in hospital longer, but were not at greater risk of dying in hospital than the patients who were not transferred.<\/jats:p>\n <\/jats:sec>","DOI":"10.5694\/mja2.51917","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T21:51:22Z","timestamp":1681163482000},"page":"474-481","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Inter\u2010hospital transfer and clinical outcomes for people with\n COVID<\/scp>\n \u201019 admitted to intensive care units in Australia: an observational cohort study"],"prefix":"10.5694","volume":"218","author":[{"given":"Courtney","family":"Cini","sequence":"first","affiliation":[{"name":"Alfred Health Melbourne VIC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ary S","family":"Neto","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre Monash University Melbourne VIC"},{"name":"Austin Hospital Melbourne VIC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aidan","family":"Burrell","sequence":"additional","affiliation":[{"name":"Alfred Health Melbourne VIC"},{"name":"Australian and New Zealand Intensive Care Research Centre Monash University Melbourne VIC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Udy","sequence":"additional","affiliation":[{"name":"Alfred Health Melbourne VIC"},{"name":"Australian and New Zealand Intensive Care Research Centre Monash University Melbourne VIC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the SPRINT\u2010SARI Australia investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,10]]},"reference":[{"key":"e_1_2_8_1_1","first-page":"46","article-title":"COVID\u201019 Australia: epidemiology report 68. Reporting period ending 20 November 2022","author":"COVID\u201019 Epidemiology and Surveillance Team","year":"2022","journal-title":"Commun Dis Intell (2018)"},{"key":"e_1_2_8_2_1","unstructured":"Australian Bureau of Statistics.Measuring Australia's excess mortality during the COVID\u201019 pandemic. 30 Mar2022.https:\/\/www.abs.gov.au\/articles\/measuring\u2010australias\u2010excess\u2010mortality\u2010during\u2010covid\u201019\u2010pandemic(viewed Apr 2022)."},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000559"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-021-00933-2"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-021-00841-5"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15680"},{"key":"e_1_2_8_7_1","unstructured":"Australian and New Zealand Intensive Care Research Centre (ANZIC\u2010RC).SPRINT\u2010SARI.https:\/\/www.anzics.com.au\/current\u2010active\u2010endorsed\u2010research\/sprint\u2010sari(viewed Mar 2022)."},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.50883"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.51590"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_8_11_1","unstructured":"Centers for Disease Control and Prevention.People with certain medical conditions. Updated Dec2022.https:\/\/www.cdc.gov\/coronavirus\/2019\u2010ncov\/need\u2010extra\u2010precautions\/people\u2010with\u2010medical\u2010conditions.html(viewed Oct 2022)."},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amj.2020.07.007"},{"issue":"19","key":"e_1_2_8_13_1","first-page":"S118","article-title":"Inter\u2010hospital communication and transfer practices during COVID\u201019 pandemic in Karachi, Pakistan. A brief overview.","volume":"36","author":"Salman S","year":"2020","journal-title":"Pak J Med Sci"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000001301"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/000313481307900929"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2001.tb143182.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhm.2515"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjqs-2018-008087"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001888-199603000-00019"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199604000-00002"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181f44abc"}],"container-title":["Medical Journal of Australia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.5694\/mja2.51917","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T05:23:48Z","timestamp":1692422628000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.5694\/mja2.51917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,10]]},"references-count":21,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,6,5]]}},"alternative-id":["10.5694\/mja2.51917"],"URL":"https:\/\/doi.org\/10.5694\/mja2.51917","archive":["Portico"],"relation":{},"ISSN":["0025-729X","1326-5377"],"issn-type":[{"value":"0025-729X","type":"print"},{"value":"1326-5377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,10]]},"assertion":[{"value":"2022-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}