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It followed best practice, involved extensive evidence synthesis and applied relevant frameworks across evidence quality, feasibility, acceptability, cost and implementation. Thirty\u2010nine societies and organisations covering 71 countries were engaged. The evidence in the assessment and management of polycystic ovary syndrome (PCOS) has generally improved in the past five years, but remains of low to moderate quality. The technical evidence report, 52 systematic reviews and analyses (approximately 6000 pages) underpin 77 evidence\u2010based and 54 consensus recommendations, with 123 practice points.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main recommendations<\/jats:title><jats:p>Changes include:\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>refinement of individual diagnostic criteria, a simplified diagnostic algorithm and inclusion of anti\u2010M\u00fcllerian hormone levels as an alternative to ultrasound in adults only, and differentiation of adolescent and adult criteria;<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>strengthening the recognition of broad features of PCOS including metabolic effects, cardiovascular disease, dermatological symptoms, sleep apnoea, a high prevalence of psychological features and a high risk of adverse pregnancy outcomes;<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>emphasising the poorly recognised, diverse burden of disease, the vital need for greater health professional education, evidence\u2010based patient information, improved models of care, shared decision making and research efforts to improve patient experience;<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>maintained emphasis on healthy lifestyle, emotional wellbeing and quality of life, with awareness and consideration of weight stigma; and<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>emphasising evidence\u2010based medical therapy and cheaper and safer fertility management.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec><jats:sec><jats:title>Changes in management as a result of this guideline<\/jats:title><jats:p>The 2023 guideline is approved by the National Health and Medical Research Council and provides clinicians and patients with clear advice on best practice in a common and neglected condition, based on the best available evidence, expert multidisciplinary input and consumer preferences. It provides vital, extensive patient and provider resources to enhance evidence\u2010based care.<\/jats:p><jats:p>The full guideline is available at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.monash.edu\/medicine\/mchri\/pcos\/guideline\">www.monash.edu\/medicine\/mchri\/pcos\/guideline<\/jats:ext-link>.<\/jats:p><\/jats:sec>","DOI":"10.5694\/mja2.52432","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T04:38:55Z","timestamp":1725338335000},"page":"389-395","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Summary of the 2023 international evidence\u2010based guideline for the assessment and management of polycystic ovary syndrome: an Australian perspective"],"prefix":"10.5694","volume":"221","author":[{"given":"Helena J","family":"Teede","sequence":"first","affiliation":[{"name":"Monash Centre for Health Research and Implementation 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