{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T12:17:13Z","timestamp":1772626633426,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014673","name":"Menzies Health Institute Queensland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014673","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010230","name":"Queensland Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010230","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Journal of Australia"],"published-print":{"date-parts":[[2025,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify the proportion of hospitalisations (inpatient admissions and emergency department presentations) of Aboriginal and Torres Strait Islander people in Queensland that were medication\u2010related and potentially preventable for nine clinical indicators of cardiovascular disease (CVD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Retrospective cohort study; analysis of linked hospitalisations and emergency department presentations data and administrative records of medical services, pharmaceuticals, and deaths.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting, participants<\/jats:title><jats:p>Aboriginal or Torres Strait Islander adults (18 years or older) admitted to Queensland public and private hospitals, 1 January 2013 \u2013 31 December 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Potentially preventable medication\u2010related hospitalisations (PPMRHs), defined by a set of clinical indicators describing CVD; deaths within 30 days of PPMRHs; hospital costs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 31 472 CVD\u2010related hospitalisations, of which 11 469 were of people with medical histories suggesting harm that was foreseeable and preventable with appropriate treatment. Of the 7886 hospitalisations with congestive heart failure, 4350 (55%) were of people with prior CVD diagnoses; 681 (16%) were associated with use of medicines known to exacerbate congestive heart failure, and 1488 (34%) were associated with underuse of angiotensin\u2010converting enzyme inhibitors, angiotensin receptor blockers, or angiotensin receptor\u2013neprilysin inhibitors. Of the 1089 hospitalisations with myocardial infarction of people who had previously experienced myocardial infarction or acute coronary syndrome events, 809 (74%) were not receiving recommended treatment at the time of hospitalisation. Of the 5417 hospitalisations with ischaemic events of people with histories including diabetes and earlier ischaemic events, 3343 (62%) were not receiving antiplatelet or lipid\u2010lowering therapy. The median cost associated with PPMRHs for the time period (2013\u20132017) was $4352 (interquartile range, $8742), and 136 (3%) of CVD\u2010related deaths within 30 days of hospital discharge followed PPMRH events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Interventions supporting targeted and timely medication safety services for Aboriginal and Torres Strait Islander people need to be reviewed and improved to reduce the numbers of avoidable hospitalisations and deaths.<\/jats:p><\/jats:sec>","DOI":"10.5694\/mja2.52600","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T06:04:51Z","timestamp":1738908291000},"page":"198-204","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Potentially preventable medication\u2010related hospitalisations with cardiovascular disease of Aboriginal and Torres Strait Islander people, Queensland, 2013\u20132017: a retrospective cohort study"],"prefix":"10.5694","volume":"222","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8128-8872","authenticated-orcid":false,"given":"Jean","family":"Spinks","sequence":"first","affiliation":[{"name":"University of Queensland  Brisbane QLD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabor","family":"Mihala","sequence":"additional","affiliation":[{"name":"University of Queensland  Brisbane QLD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Warren","family":"Jennings","sequence":"additional","affiliation":[{"name":"University of Queensland  Brisbane QLD"},{"name":"Metro South Hospital and Health Service  Brisbane QLD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S","family":"Ware","sequence":"additional","affiliation":[{"name":"Griffith University  Gold Coast QLD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa M","family":"Kalisch Ellett","sequence":"additional","affiliation":[{"name":"University of South Australia  Adelaide SA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6811-8991","authenticated-orcid":false,"given":"Elizabeth E","family":"Roughead","sequence":"additional","affiliation":[{"name":"University of South Australia  Adelaide SA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Williamson","sequence":"additional","affiliation":[{"name":"Queensland Health  Brisbane QLD"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"e_1_2_9_1_1","unstructured":"Pharmaceutical Care Network Europe Association.Classification for drug related problems v9.00.2019.https:\/\/www.pcne.org\/upload\/files\/334_PCNE_classification_V9\u20100.pdf(viewed Oct 2023)."},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-011-9583-1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-019-05463-z"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzs015"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-031369"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-004625"},{"key":"e_1_2_9_7_1","unstructured":"Australian Department of Health and Aged Care.Reporting for the Remote Area Aboriginal Health Services Program. 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