{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T09:47:11Z","timestamp":1782467231672,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Journal of Australia"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study quantifies the short\u2010term risk profiles of seven severe acute respiratory syndrome coronavirus 2 virus (SARS\u2010CoV\u20102) vaccines\u2014Comirnaty Bivalent BA.1, Comirnaty Bivalent BA.4\u20105, Comirnaty XBB.1.5, Spikevax Bivalent BA.1, Spikevax Bivalent BA.4\u20105, Spikevax XBB.1.5 and Nuvaxovid\u2014administered as booster doses in Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>This is a survey study using data collected from online surveys sent via AusVaxSafety, the Australian active vaccine safety surveillance system, 3\u2009days post\u2010vaccination, soliciting reports of adverse events following vaccination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants and Setting<\/jats:title>\n                    <jats:p>Individuals 18\u2009years and older who received a SARS\u2010CoV\u20102 vaccine booster at an AusVaxSafety vaccine surveillance site between 1 January 2023 and 31 August 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Bayesian logistic regression was used to estimate risk of reported adverse events, seeking medical advice and impact on daily activities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 197,476 respondents, 59,089 (29.9%) reported at least one adverse event, of which the most commonly reported symptoms were injection site reaction (23.8% [46,988\/197,476]) and fatigue (19.4% [38,352\/197,476]). Symptom resolution was reported by 69.9% (41,299\/59,089) by day 3 and 5.6% (11,006\/197,476) reported any time lost from daily activities. The unadjusted proportion of respondents who sought medical advice was higher in those who received Spikevax XBB.1.5 (1.2% [212\/17,551]) than the other vaccines (0.5% [379\/69,493] to 0.7% [147\/20,271]), but the modelled, adjusted mean risk of medical advice was similar (&lt;\u20092.5%) across subgroups for vaccine brands, co\u2010administered vaccines, medical conditions, age, sex and Indigenous status. The modelled risk of any adverse event at age 40\u2009years ranged from 35.2% (95% credible interval [CrI], 32.2%\u201338.5%) for men who had received Comirnaty XBB.1.5 to 75.5% (95% CrI, 71.9%\u201378.8%) for women who had received Spikevax XBB.1.5. At age 80\u2009years, this risk was lowest across all vaccines, ranging from 12.0% (95% CrI, 11.2%\u201313.0%) for men who had received Comirnaty BA4\u20105 to 36.7% (95% CrI, 34.6%\u201338.7%) for women who had received Spikevax XBB.1.5.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of this study confirm the short\u2010term safety and low impact on daily living of SARS\u2010CoV\u20102 booster vaccine administration to Australian adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5694\/mja2.70227","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T03:15:36Z","timestamp":1781666136000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Short\u2010Term Safety and Adverse Event Risk Profiles for SARS\u2010CoV\u20102 Booster Vaccine Doses in Australian 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