{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T22:00:17Z","timestamp":1782511217591,"version":"3.54.5"},"reference-count":38,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy Curr"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>Prognostication after cardiac arrest often depends primarily on neurological function, and characterizing the extent of neurological injury hinges on neurophysiological testing and clinical neurological examination. The presence of early posthypoxic myoclonus (PHM) following cardiac arrest had been invariably associated with poor outcome, but more recent studies have shown that those with early PHM may survive with good neurological function. Electroencephalographic patterns suggestive of severe brain injury may be more valuable than the presence of PHM itself in portending poor functional status, and phenotyping PHM may also be useful in delineating benign and malignant forms. Patients with early PHM should be evaluated similarly to others who suffer cardiac arrest by using a multimodal approach in determining prognosis until further studies are performed that better characterize early PHM subtypes and their outcomes.<\/jats:p>","DOI":"10.5698\/1535-7597.17.5.265","type":"journal-article","created":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T17:35:41Z","timestamp":1509557741000},"page":"265-272","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Myoclonus after Cardiac Arrest: Where Do We Go from Here?"],"prefix":"10.1177","volume":"17","author":[{"given":"Brin","family":"Freund","sequence":"first","affiliation":[{"name":"Johns Hopkins Hospital, Department of Neurology, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W.","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bayview Medical Center, Department of Neurology, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,9,1]]},"reference":[{"key":"bibr1-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(16)00015-6"},{"key":"bibr2-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001742"},{"key":"bibr3-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1177\/1550059416643193"},{"key":"bibr4-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1177\/0885066615571533"},{"key":"bibr5-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24697"},{"key":"bibr6-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410350219"},{"key":"bibr7-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2009.05939.x"},{"key":"bibr8-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.40.3.253"},{"key":"bibr9-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000227183.21314.cd"},{"key":"bibr10-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000191308.22233.88"},{"key":"bibr11-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-5-14"},{"key":"bibr12-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1159\/000086755"},{"key":"bibr13-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000334205.81148.31"},{"key":"bibr14-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-010-9412-8"},{"key":"bibr15-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(10)61038-8"},{"key":"bibr16-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-011-9565-0"},{"key":"bibr17-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31827f089d"},{"key":"bibr18-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22133"},{"key":"bibr19-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1186\/2197-425X-3-S1-A198"},{"key":"bibr20-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2012.11.001"},{"key":"bibr21-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-015-3834-x"},{"key":"bibr22-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2015.08.009"},{"key":"bibr23-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.5334\/tohm.323"},{"key":"bibr24-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000880"},{"issue":"1","key":"bibr25-1535-7597.17.5.265","first-page":"S285","volume":"21","author":"Youn TS","year":"2014","journal-title":"Neurocrit Care"},{"issue":"10","key":"bibr26-1535-7597.17.5.265","doi-asserted-by":"crossref","first-page":"S11004","DOI":"10.1212\/WNL.82.10_supplement.S11.004","volume":"82","author":"Amorim E","year":"2014","journal-title":"Neurology"},{"key":"bibr27-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-12-63"},{"key":"bibr28-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2011.09.017"},{"key":"bibr29-1535-7597.17.5.265","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/ana.21984","volume":"67","author":"Rossetti AO","year":"2010","journal-title":"Ann Neurol"},{"key":"bibr30-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2011.02.020"},{"key":"bibr31-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2013.05.013"},{"key":"bibr32-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2015.06.010"},{"key":"bibr33-1535-7597.17.5.265","doi-asserted-by":"crossref","unstructured":"FreundB, KaplanPW. Post-hypoxic myoclonus: Differentiating benign and malignant etiologies in diagnosis and prognosis.\n                      Clin Neurophys Prac\n                      2017. In press. doi: http:\/\/dx.doi.org\/10.1016\/j.cnp.2017.03.003","DOI":"10.1016\/j.cnp.2017.03.003"},{"key":"bibr34-1535-7597.17.5.265","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870150703"},{"key":"bibr35-1535-7597.17.5.265","unstructured":"ReynoldsAS, HolmesMG, RobinsonD, RothW, ParkS, RohD, AgarwalS, ClaassenJ. Phenotypes of post-anoxic myoclonus do not predict outcome. In: Proceedings from the Annual Meeting of the American Clinical Neurophysiology Society, Phoenix, AZ, February 2017. Abstract F-4."},{"key":"bibr36-1535-7597.17.5.265","doi-asserted-by":"crossref","unstructured":"Mikhaeil-DemoY, GavvalaJ, BellinskiI, MackenM, NarechaniaA, TemplerJ, VanHaerentsSA, SchueleS. Clinical classification of post anoxic myoclonic status. 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