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The feeding trial lasted up to 12 weeks of age.Results: Rabbits MS-Prob diet had significantly higher daily and final body weight recording also the best of feed efficiency compared to control group. Rabbits in MS-Prob group showed improved slaughter weight and carcass dressing yield. No significant effect was found on meat protein, lipids and ash contents. Serum total cholesterol, low-density lipoprotein, high-density lipoprotein and triglycerides decreased significantly in rabbits fed the test-diet. In rabbits fed MS-Prob, the activity of glutathione peroxidase, glutathione S-transferase, catalase and superoxide dismutase increased significantly, whereas the level of thiobarbituric acid-reactive substance decreased significantly. Caecal pH, ammonia-N and total volatile fatty acids (VFAs) were not significantly influenced by dietary treatments. Conversely, VFAs molar proportions were statistically affected by diets, with higher acetic and butyric acid concentrations in caecum of rabbits fed MS-Prob. Feeding of MS-Prob reduced harmful bacterial growth (&lt;i&gt;Escherichia coli&lt;\/i&gt;, &lt;i&gt;Bacillus&lt;\/i&gt; spp., &lt;i&gt;Clostridium&lt;\/i&gt; spp.) while promoting beneficial bacteria (&lt;i&gt;Lactobacillus&lt;\/i&gt; spp., &lt;i&gt;Bacteroides&lt;\/i&gt; spp.). Moreover, MS-Prob positively influences rabbit gut histomorphology, showing higher villus height, villus width, and crypt depth.Conclusion: This study indicated that MS-Prob (Slab51) supplementation stimulated the performance of growing rabbits and positively affected blood serum parameters, intestinal morphology, and caecal environment and microbiota.<\/jats:p>","DOI":"10.5713\/ab.24.0716","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T09:19:01Z","timestamp":1737710341000},"page":"1247-1258","update-policy":"https:\/\/doi.org\/10.5713\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effects of a multi-strain probiotic on productive traits, antioxidant defence, caecal microbiota and short\u2011chain fatty acid profile, and intestinal histomorphology in 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