{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T19:50:49Z","timestamp":1793044249240,"version":"4.5.0"},"reference-count":41,"publisher":"Becaris Publishing Limited","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Comp. Eff. Res."],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>\n                    <jats:bold>Aim:<\/jats:bold>\n                    This retrospective cohort study assessed differences in procedure-related complications and death among old patients with atrial fibrillation (AF) undergoing catheter ablation (CA) procedure with versus without use of intracardiac echocardiography (ICE) and advanced three-dimensional (3D) electroanatomical mapping.\n                    <jats:bold>Materials &amp; methods:<\/jats:bold>\n                    Using the Medicare Database, a retrospective cohort of AF patients \u226565\u00a0years of age who underwent CA procedure were identified, and categorized into two cohorts: CA without ICE\/3D mapping versus CA with ICE\/3D mapping. Outcomes including a composite of complications (any), cardiac perforation, esophageal fistula and death, respectively, in the 30-day period post-CA were assessed. Inverse probability of treatment weighting method was used for covariate balancing. Cox regression models were performed to evaluate outcomes.\n                    <jats:bold>Results:<\/jats:bold>\n                    There were 35,490 patients in CA without ICE\/3D mapping cohort and 170,762 in the CA with ICE\/3D mapping cohort. Cox regression model revealed that patients who underwent CA without ICE\/3D mapping use were \u223c3.5-times more likely to have 30-day any complication versus those who had CA with ICE\/3D mapping (7.3% vs 2.2%, log-rank test p\u00a0&lt;\u00a00.001; hazard ratio: 3.507; 95% CI: 3.307\u20133.720, p\u00a0&lt;\u00a00.001). The incidence of cardiac perforation (2.5% vs 0.1%, log-rank test p\u00a0&lt;\u00a00.001), atrio-esophageal fistula (0.03% vs 0.01%, log-rank test p\u00a0=\u00a00.03) and death (1.6% vs 0.2%, log-rank test p\u00a0&lt;\u00a00.001) were significantly higher among patients without ICE\/3D mapping versus those who had CA with ICE\/3D mapping.\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    The absence of ICE and 3D mapping during CA procedures was associated with significantly increased risk of complications and death among Medicare eligible patients with AF.\n                  <\/jats:p>","DOI":"10.57264\/cer-2026-0037","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T11:23:32Z","timestamp":1782127412000},"source":"Crossref","is-referenced-by-count":1,"title":["Use of intracardiac echocardiography and three-dimensional mapping during catheter ablation for atrial fibrillation is associated with reduced complications: a retrospective analysis of United States Medicare Fee-For-Service Database"],"prefix":"10.57264","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8571-3872","authenticated-orcid":false,"given":"Yiran","family":"Rong","sequence":"first","affiliation":[{"name":"MedTech Epidemiology &amp; Real-World Data Sciences, Johnson &amp; Johnson, New Brunswick, NJ 08933, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Wei","sequence":"additional","affiliation":[{"name":"Health Economics &amp; Market Access, Johnson &amp; Johnson MedTech Electrophysiology Irvine, CA 92618, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Corriveau","sequence":"additional","affiliation":[{"name":"Health Economics &amp; Market Access, Johnson &amp; Johnson MedTech Electrophysiology Irvine, CA 92618, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2478-1724","authenticated-orcid":false,"given":"Rahul","family":"Khanna","sequence":"additional","affiliation":[{"name":"MedTech Epidemiology &amp; Real-World Data Sciences, Johnson &amp; Johnson, New Brunswick, NJ 08933, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36897","reference":[{"key":"e_1_3_8_3_2","volume-title":"Projections of Cardiovascular Disease Prevalence and Costs: 2015\u20132035","author":"Khavjou O","year":"2016","unstructured":"Khavjou O, Phelps D, Leib A. 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