{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:09:01Z","timestamp":1785449341085,"version":"3.56.0"},"reference-count":20,"publisher":"Editorial Committee of Annals of Thoracic and Cardiovascular Surgery","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ATCS","Ann Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2016]]},"DOI":"10.5761\/atcs.cr.15-00154","type":"journal-article","created":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T22:04:18Z","timestamp":1441145058000},"page":"116-121","source":"Crossref","is-referenced-by-count":13,"title":["Lung Cancer Detected 5 Years after Resection of Cancer of Unknown Primary in a Mediastinal Lymph Node: A Case Report and Review of Relevant Cases from the Literature"],"prefix":"10.5761","volume":"22","author":[{"given":"Hidenori","family":"Kawasaki","sequence":"first","affiliation":[{"name":"Department of Surgery, National Hospital Organization Okinawa National Hospital, Okinawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunari","family":"Arakaki","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospital, University of the Rykyus, Okinawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naohiro","family":"Taira","sequence":"additional","affiliation":[{"name":"Department of Surgery, National Hospital Organization Okinawa National Hospital, Okinawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomonori","family":"Furugen","sequence":"additional","affiliation":[{"name":"Department of Surgery, National Hospital Organization Okinawa National Hospital, Okinawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaharu","family":"Ichi","sequence":"additional","affiliation":[{"name":"Department of Surgery, National Hospital Organization Okinawa National Hospital, Okinawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomofumi","family":"Yohena","sequence":"additional","affiliation":[{"name":"Department of Surgery, National Hospital Organization Okinawa National Hospital, Okinawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsutomu","family":"Kawabata","sequence":"additional","affiliation":[{"name":"Department of Surgery, National Hospital Organization Okinawa National Hospital, Okinawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3757","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Holmes FF, Fouts TL. Metastatic cancer of unknown primary site. Cancer 1970; 26: 816-20.","DOI":"10.1002\/1097-0142(197010)26:4<816::AID-CNCR2820260413>3.0.CO;2-R"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Pavlidis N, Briasoulis E, Hainsworth J, et al. Diagnostic and therapeutic management of cancer of an unknown primary. Eur J Cancer 2003; 39: 1990-2005.","DOI":"10.1016\/S0959-8049(03)00547-1"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Fizazi K, Greco FA, Pavlidis N, et al. Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2011; 22 Suppl 6: vi64-8.","DOI":"10.1093\/annonc\/mdr389"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Kohdono S, Ishida T, Fukuyama Y, et al. Lymph node cancer of the mediastinal or hilar region with an unknown primary site. J Surg Oncol 1995; 58: 196-200.","DOI":"10.1002\/jso.2930580311"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Riquet M, Badoual C, le Pimpec BF, et al. Metastatic thoracic lymph node carcinoma with unknown primary site. Ann Thorac Surg 2003; 75: 244-9.","DOI":"10.1016\/S0003-4975(02)04119-X"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Cafferata MA, Chiaramondia M, Monetti F, et al. Complete spontaneous remission of non-small-cell lung cancer: a case report. Lung Cancer 2004; 45: 263-6.","DOI":"10.1016\/j.lungcan.2004.01.026"},{"key":"7","unstructured":"7) Rosai J, ed. Ackerman\u2019s surgical pathology. Lymph node inclusions, 8th ed. St. Louis: Mosby, 1996."},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Fellegara G, Carcangiu ML, Rosai J. Benign epithelial inclusions in axillary lymph nodes: report of 18 cases and review of the literature. Am J Surg Pathol 2011; 35: 1123-33.","DOI":"10.1097\/PAS.0b013e3182237985"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Kwee TC, Kwee RM. Combined FDG-PET\/CT for the detection of unknown primary tumors: systematic review and meta-analysis. Eur Radiol 2009; 19: 731-44.","DOI":"10.1007\/s00330-008-1194-4"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Kita Y, Kondo D. Occult lung cancer with sarcoidosis; a case report. The primary lesion appeared on chest X-ray taken 18 months after resection of mediastinal lymph node metastases. Jpn J Chest Surg 1996; 10: 488-93. (in Japanese with English abstract)","DOI":"10.2995\/jacsurg.10.488"},{"key":"11","unstructured":"11) Matsuge S, Hosokawa Y, Sato K, et al. An occult intrapulmonary large cell neuroendocrine carcinoma presenting mediastinal lymph adenopathy as an initial manifestation. Jpn J Chest Dis 1999; 58: 668-72. (in Japanese with English abstract)"},{"key":"12","unstructured":"12) Sakuraba M, Mae M, Oonuki T, et al. Mediastinal and hilar lymph node of cancer unknown origin: 3 case reports. J Jpn Respir Soc 1999; 37: 72-7. (in Japanese with English abstract)"},{"key":"13","unstructured":"13) Chen F, Tatsumi A, Nii E, et al. Four cases of cancer of unknown primary site that manifested as mediastinal metastatic lesions. J Jpn Respir Soc 1999; 37: 1003-7. (in Japanese with English abstract)"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Suzuki Y, Ogawa N, Ishiwa N, et al. Resection of a primary lung lesion after resection of a malignant hilar lymph node of unknown origin. Jpn J Lung Cancer 2002; 42: 283-7. (in Japanese with English abstract)","DOI":"10.2482\/haigan.42.283"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Hara H, Suzuki M, Takagi T, et al. A case of mediastinal lymph node metastases followed by appearance of primary multiple lung cancer. Jpn J Lung Cancer 2008; 48: 130-4. (in Japanese with English abstract)","DOI":"10.2482\/haigan.48.130"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Nishikawa T, Ninomiya T, Fujiwara T, et al. A case of lung cancer after chemotherapy of hilar and mediastinum lymphnode cancer on unknown origin. J Jpn Surg Assoc 2010; 71: 2000-4. (in Japanese with English abstract)","DOI":"10.3919\/jjsa.71.2000"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Baba T, Uramoto H, Yamada S, et al. Three cases of mediastinal lymph node carcinoma with an unknown primary site. Jpn J Chest Surg 2011; 25: 175-81. (in Japanese with English abstract)","DOI":"10.2995\/jacsurg.25.175"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Higuchi T, Nagata A, Hamada T, et al. A case of primary lung cancer developing 9 years after surgery for metastatic mediastinal lymph node carcinoma. Jpn J Chest Surg 2015; 29: 220-5. (in Japanese with English abstract)","DOI":"10.2995\/jacsurg.29.220"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Hayasi K. A case report of a long-surviving patient with mediastinal lymph node carcinoma from an unknown primary site, with a review of 31 cases reported in Japan. Jpn J Chest Surg 2007; 21: 624-9. (in Japanese with English abstract)","DOI":"10.2995\/jacsurg.21.624"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Morio A, Miyamoto H, Izumi H, et al. A case report of adenocarcinoma of unknown origin metastatic to the mediastinal lymph nodes with a review of 21 cases reported in Japan. Jpn J Lung Cancer 2001; 41: 73-8. (in Japanese with English abstract)","DOI":"10.2482\/haigan.41.73"}],"container-title":["Annals of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/atcs\/22\/2\/22_cr.15-00154\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T02:33:15Z","timestamp":1567132395000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/atcs\/22\/2\/22_cr.15-00154\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.5761\/atcs.cr.15-00154","relation":{},"ISSN":["1341-1098","2186-1005"],"issn-type":[{"value":"1341-1098","type":"print"},{"value":"2186-1005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}