{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T18:38:30Z","timestamp":1785868710348,"version":"3.56.0"},"reference-count":0,"publisher":"Canadian Geriatrics Society","issue":"4","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/2.5\/ca\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can Geriatr J"],"abstract":"<jats:p>Background\u00a0\nOlder age increases the likelihood of chronic diseases and polypharmacy with the likelihood of potentially inappropriate medications (PIMs) in secondary and tertiary care levels, but in the primary care settings of Thailand there still is a need for more evidence. This study aimed to examine the prevalence of PIM in primary care settings, and to identify factors that influence the use of PIM.\u00a0\nMethods\u00a0\nA cross-sectional retrospective study was conducted in 2017. Eight primary care units from four regions of Thailand were randomly selected. People aged \u2265 60 years in the eight units were studied as participants. The List of Risk Drugs for Thai Elderly (LRDTE) was used as the reference. Multivariate logistic regression was carried out to identify factors that influence.\u00a0\nResults\u00a0\nA total of 4,848 patients aged \u226560 years with 20,671 prescriptions were studied. The mean age was 70.7\u00b18.3 years for males, and 61.2% for females. A little more than 5% (5.1%) had \u2265 3 chronic diseases and 15.0% received polypharmacy ( \u22655 medications). The prevalence of prescriptions with PIMs was 65.9%. The most frequent PIMs were antidepressants: amitriptyline (28.1%), antihistamines: dimenhydrinate (22.4%) and chlorpheniramine maleate (CPM) (11.2%); and Benzodiazepines: lorazepam (6.5%). Three factors that significantly influenced prescribing of PIMs were polypharmacy (adjusted OR 3.51; 95% CI 2.81-4.32), having \u22653 chronic diseases (adjusted OR 1.44; 95% CI 1.04-2.01), and age \u226575 years (adjusted OR 1.18; 95% CI 1.01-1.38).\u00a0\nConclusion\u00a0\nMore than two-thirds of elderly Thai patients in the primary care settings were prescribed PIMs. Multidisciplinary prescription review and PIM screening in patients aged \u226575 years who have \u22653 chronic diseases or polypharmacy should be implemented in primary care and supportive computerized PIMs alert system is needed.\u00a0<\/jats:p>","DOI":"10.5770\/cgj.24.516","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T22:55:42Z","timestamp":1638399342000},"page":"332-340","source":"Crossref","is-referenced-by-count":11,"title":["Prevalence and Factors that Influence Potentially Inappropriate Medication Use among Thai Elderly in Primary Care Settings"],"prefix":"10.5770","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8655-7154","authenticated-orcid":false,"given":"Pasitpon","family":"Vatcharavongvan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3660-4490","authenticated-orcid":false,"given":"Vanida","family":"Prasert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanuttha","family":"Ploylearmsang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1672-1016","authenticated-orcid":false,"given":"Viwat","family":"Puttawanchai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3968","published-online":{"date-parts":[[2021,12,1]]},"container-title":["Canadian Geriatrics Journal"],"original-title":[],"link":[{"URL":"https:\/\/cgjonline.ca\/index.php\/cgj\/article\/download\/516\/732","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cgjonline.ca\/index.php\/cgj\/article\/download\/516\/745","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cgjonline.ca\/index.php\/cgj\/article\/download\/516\/732","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T22:55:42Z","timestamp":1638399342000},"score":1,"resource":{"primary":{"URL":"https:\/\/cgjonline.ca\/index.php\/cgj\/article\/view\/516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,1]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,12,1]]}},"URL":"https:\/\/doi.org\/10.5770\/cgj.24.516","relation":{},"ISSN":["1925-8348"],"issn-type":[{"value":"1925-8348","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,1]]}}}