{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T16:43:41Z","timestamp":1726505021286},"reference-count":14,"publisher":"California Digital Library (CDL)","issue":"4","license":[{"start":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T00:00:00Z","timestamp":1568764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Neurofibromatosis (NF) is a common autosomal dominant disorder that can be subdivided into type 1, type 2, and schwannomatosis. Patients with NF1 typically develop caf\u00e9-au-lait spots, scoliosis, and benign neurofibromas. In addition, NF1 predisposes to vascular complications including stenosis, arterial ectasia, and aneurysms. Here, we report the case of an otherwise healthy 32-year-old man who developed a fatal tension hemothorax due to vertebral artery aneurysm rupture. Based on the available literature, we discuss the presentation, workup, and available therapeutic approaches to this complication of neurofibromatosis.<\/jats:p>","DOI":"10.5811\/cpcem.2019.7.43432","type":"journal-article","created":{"date-parts":[[2019,11,5]],"date-time":"2019-11-05T17:53:25Z","timestamp":1572976405000},"page":"364-368","source":"Crossref","is-referenced-by-count":0,"title":["Fatal Tension Hemothorax Combined With Exanguination: A Rare Complication of Neurofibromatosis"],"prefix":"10.5811","volume":"3","author":[{"given":"Roz","family":"Bidad","sequence":"first","affiliation":[{"name":"University of Vermont Medical Center, Department of Emergency Medicine, Burlington, Vermont"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Hall","sequence":"additional","affiliation":[{"name":"University of Vermont Medical Center, Department of Emergency Medicine, Burlington, Vermont"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eike","family":"Blohm","sequence":"additional","affiliation":[{"name":"University of Vermont Medical Center, Department of Emergency Medicine, Burlington, Vermont"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"29705","published-online":{"date-parts":[[2019,9,18]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Moro K, Kameyama H, Abe K, et al. Left colic artery aneurysm rupture after stent placement for abdominal aortic aneurysm associated with neurofibromatosis type 1. Surg Case Rep. 2019;5(1):12.","DOI":"10.1186\/s40792-019-0570-4"},{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Pezzetta E, Paroz A, Ris HB, et al. Spontaneous hemothorax associated with von Recklinghausen\u2019s disease. Eur J Cardiothorac Surg. 2003;23(6):1062-4.","DOI":"10.1016\/S1010-7940(03)00145-3"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Zhang K, Song J, Xiong W, et al. Massive spontaneous hemorrhage in giant type 1 neurofibromatosis in soft tissue of chest wall. J Thorac Cardiovasc Surg. 2012;144(3):e92-3.","DOI":"10.1016\/j.jtcvs.2012.05.046"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Fohrding LZ, Sellmann T, Angenendt S, et al. A case of lethal spontaneous massive hemothorax in a patient with neurofibromatosis 1. J Cardiothorac Surg. 2014;9:172.","DOI":"10.1186\/s13019-014-0172-y"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Pulivarthi S, Simmons B, Shearen J, et al. Spontaneous hemothorax associated with neurofibromatosis type I: A review of the literature. J Neurosci Rural Pract. 2014;5(3):269-71.","DOI":"10.4103\/0976-3147.133592"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"D\u2019Errico S, Martelloni M, Cafarelli FP, et al. Neurofibromatosis 1 and massive hemothorax: a fatal combination. Forensic Sci Med Pathol. 2018;14(3):377-80.","DOI":"10.1007\/s12024-018-0001-z"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Hongsakul K, Rookkapan S, Tanutit P, et al. Spontaneous massive hemothorax in a patient with neurofibromatosis type 1 with successful transarterial embolization. Korean J Radiol. 2013;14(1):86-90.","DOI":"10.3348\/kjr.2013.14.1.86"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Arai K, Sanada J, Kurozumi A, et al. Spontaneous hemothorax in neurofibromatosis treated with percutaneous embolization. Cardiovasc Intervent Radiol. 2007;30(3):477-9.","DOI":"10.1007\/s00270-006-0056-1"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Hieda M, Toyota N, Kakizawa H, et al. Endovascular therapy for massive haemothorax caused by ruptured extracranial vertebral artery aneurysm with neurofibromatosis Type 1. Br J Radiol. 2007;80(952):e81-4.","DOI":"10.1259\/bjr\/47379807"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"Byard RW. Forensic considerations in cases of neurofibromatosis: an overview. J Forensic Sci. 2007;52(5):1164-70.","DOI":"10.1111\/j.1556-4029.2007.00512.x"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Sandhu C and Sabharwal T. Spontaneous hemothorax in patients with neurofibromatosis treated with percutaneous embolization. Cardiovasc Intervent Radiol. 2008;31(6):1260-1.","DOI":"10.1007\/s00270-007-9274-4"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Jeong SC, Kim JJ, Choi SY et al. Successful surgical treatment of massive spontaneous hemothorax due to intrathoracic secondary degeneration of a neurofibroma from mediastinal involvement of type 1 neurofibromatosis. J Thorac Dis. 2018;10(3):E203-6.","DOI":"10.21037\/jtd.2018.01.170"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"Strambo D, Peruzzotti-Jametti L, Semerano A, et al. Treatment challenges of a primary vertebral artery aneurysm causing recurrent ischemic strokes. Case Rep Neurol Med. 2017;2017:2571630.","DOI":"10.1155\/2017\/2571630"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Uneda A, Suzuki K, Okubo S et al. Neurofibromatosis type 1-associated extracranial vertebral artery aneurysm complicated by vertebral arteriovenous fistula after rupture: case report and literature review. World Neurosurg. 2016;96:609.e13-609.e18.","DOI":"10.1016\/j.wneu.2016.09.036"}],"container-title":["Clinical Practice and Cases in Emergency Medicine"],"original-title":[],"deposited":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T19:00:28Z","timestamp":1573153228000},"score":1,"resource":{"primary":{"URL":"https:\/\/escholarship.org\/uc\/item\/6fv1b3rc"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,18]]},"references-count":14,"issue-title":["Clinical Practice and Cases in Emergency Medicine"],"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,10,31]]}},"URL":"https:\/\/doi.org\/10.5811\/cpcem.2019.7.43432","relation":{},"ISSN":["2474-252X","2474-252X"],"issn-type":[{"type":"electronic","value":"2474-252X"},{"type":"print","value":"2474-252X"}],"subject":[],"published":{"date-parts":[[2019,9,18]]}}}