{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T12:27:18Z","timestamp":1765369638919},"reference-count":7,"publisher":"California Digital Library (CDL)","issue":"3","license":[{"start":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T00:00:00Z","timestamp":1592179200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Case Presentation: A 38-year-old male presented to the emergency department with methamphetamine-induced agitation. Physical exam showed clouding of the left cornea, with gelatinous appearance and associated conjunctivitis, consistent with corneal melt, or keratolysis. \n\nDiscussion: Keratolysis is dissolution of the corneal stroma that can lead to corneal ulceration and vision loss. Smoking stimulants has been shown to be associated with this pattern of ocular injury, although this is a relatively rare presentation. Acute keratolysis is a unique complication of methamphetamine preparation and ingestion via smoking that can lead to corneal ulceration and loss of vision.<\/jats:p>","DOI":"10.5811\/cpcem.2020.3.43981","type":"journal-article","created":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T17:23:00Z","timestamp":1597339380000},"page":"472-473","source":"Crossref","is-referenced-by-count":3,"title":["Keratolysis Associated with Methamphetamine Use \u2013 Incidental Diagnosis of Corneal Melt in a Patient with Acute Methamphetamine Intoxication"],"prefix":"10.5811","volume":"4","author":[{"given":"Jagdipak","family":"Heer","sequence":"first","affiliation":[{"name":"Kern Medical Center, Department of Emergency Medicine, Bakersfield, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean","family":"Heavey","sequence":"additional","affiliation":[{"name":"Kern Medical Center, Department of Emergency Medicine, Bakersfield, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Quesada","sequence":"additional","affiliation":[{"name":"Kern Medical Center, Department of Emergency Medicine, Bakersfield, California; LAC+ USC Medical Center, Department of Emergency Medicine, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip","family":"Agu\u00ec\u00f1iga-Navarrete","sequence":"additional","affiliation":[{"name":"Kern Medical Center, Department of Emergency Medicine, Bakersfield, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madison","family":"Garrett","sequence":"additional","affiliation":[{"name":"Kern Medical Center, Department of Emergency Medicine, Bakersfield, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kieron","family":"Barkataki","sequence":"additional","affiliation":[{"name":"Kern Medical Center, Department of Emergency Medicine, Bakersfield, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"29705","published-online":{"date-parts":[[2020,6,15]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Nash EA and Margo CE. Patterns of emergency department visits for disorders of the eye and ocular adnexa.\u00a0Arch Ophthalmol.\u00a01998;116(9):1222-6.","DOI":"10.1001\/archopht.116.9.1222"},{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Hossain P. The corneal melting point. Eye (Lond). 2012;26(8):1029-30.","DOI":"10.1038\/eye.2012.136"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Poulsen EJ, Mannis MJ, Chang SD. Keratitis in methamphetamine abusers. Cornea. 1996;15(5):477-82.","DOI":"10.1097\/00003226-199609000-00007"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Ghosheh FR, Ehlers JP, Ayres BD, et al. Corneal ulcers associated with aerosolized crack cocaine use. Cornea. 2007;26(8):966-9.","DOI":"10.1097\/ico.0b013e3180cfe716"},{"key":"ref4","unstructured":"Artigiani EE, Hsu MH, McCandlish D, et al. (2018).Methamphetamine: A Regional Drug Crisis. College Park, MD: National Drug Early Warning System."},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Tucci V, Siever K, Matorin A, et al. Down the rabbit hole: emergency department medical clearance of patients with psychiatric or behavioral emergencies. Emerg Med Clin North Am. 2015;33(4):721-37.","DOI":"10.1016\/j.emc.2015.07.002"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Klein LR, Cole JB, Driver BE, et al. Unsuspected critical illness among emergency department patients presenting for acute alcohol intoxication. Ann Emerg Med. 2018;71(3):279-88.","DOI":"10.1016\/j.annemergmed.2017.07.021"}],"container-title":["Clinical Practice and Cases in Emergency Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T19:16:56Z","timestamp":1600283816000},"score":1,"resource":{"primary":{"URL":"https:\/\/escholarship.org\/uc\/item\/4962t66v"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,15]]},"references-count":7,"issue-title":["Clinical Practice and Cases in Emergency Medicine"],"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,8,6]]}},"URL":"https:\/\/doi.org\/10.5811\/cpcem.2020.3.43981","relation":{},"ISSN":["2474-252X","2474-252X"],"issn-type":[{"type":"electronic","value":"2474-252X"},{"type":"print","value":"2474-252X"}],"subject":[],"published":{"date-parts":[[2020,6,15]]}}}