{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T04:30:21Z","timestamp":1782275421539,"version":"3.54.5"},"reference-count":5,"publisher":"California Digital Library (CDL)","issue":"4","license":[{"start":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T00:00:00Z","timestamp":1599609600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction: Neurological complaints are a common presenting symptom seen by the emergency physician. However, the Miller-Fisher variant of Guillain-Barr\u00e9 syndrome is a rare cause of neurological complaints seen in the emergency department. \n\nCase Report: A 26-year-old male presented with dysphonia and bilateral hand and feet paresthesia after a recent diarrheal illness. Examination revealed the absence of tricep, brachioradialis, patellar and Achilles tendon reflexes bilaterally, and difficulty with phonation. Lumbar puncture revealed the presence of anti-GQ1b antibodies, and the patient was diagnosed with Miller-Fisher variant of Guillain-Barr\u00e9. \n\nDiscussion: Miller-Fisher syndrome is an acute, autoimmune response that typically follows either an upper respiratory or diarrheal illness. Typically associated with dysfunction of cranial nerves three, four, and six, Miller-Fisher syndrome may present with facial paralysis, opthalmoplegia, arefexia, or ataxia. Lumbar puncture with the presence of anti-GQ1b antibodies is indicative. Treatment could include supportive respiratory care, intravenous immunoglobulin therapy, or plasmapheresis. \n\nConclusion: Miller-Fisher syndrome is a rare form of Guillain-Barr\u00e9 syndrome that the emergency provider should include in the differential when faced with a patient with cranial nerve dysfunction.<\/jats:p>","DOI":"10.5811\/cpcem.2020.7.48507","type":"journal-article","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T06:13:34Z","timestamp":1605593614000},"page":"653-655","source":"Crossref","is-referenced-by-count":9,"title":["Miller-Fisher Syndrome: A Case Report and Review of the Literature"],"prefix":"10.5811","volume":"4","author":[{"given":"Justina","family":"Truong","sequence":"first","affiliation":[{"name":"Kingman Regional Medical Center, Department of Emergency Medicine, Kingman, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff","family":"Conley","sequence":"additional","affiliation":[{"name":"Kingman Regional Medical Center, Department of Emergency Medicine, Kingman, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Ashurst","sequence":"additional","affiliation":[{"name":"Kingman Regional Medical Center, Department of Emergency Medicine, Kingman, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"29705","published-online":{"date-parts":[[2020,9,9]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Pope J and Edlow J. Avoiding misdiagnosis in patients with neurological emergencies. Emerg Med Int. 2012;2012(7):949275.","DOI":"10.1155\/2012\/949275"},{"key":"ref1","unstructured":"Kozminski MP. Miller Fisher variant of Guillain-Barre syndrome: a report of case. J Am Osteopath Assoc. 2008;108(2):51-2."},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Willison HJ, Jacbos BC, van Doorn PA. Guillain-Barre syndrome. Lancet. 2016;388(10045):717-27.","DOI":"10.1016\/s0140-6736(16)00339-1"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Yuki N and Hartung H. Guillain-Barre syndrome. N Engl J Med. 2012;366(24):2294-304.","DOI":"10.1056\/NEJMra1114525"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Othman B, Raabe J, Kini A, et al. Update: the Miller Fisher variants of Guillain-Barre syndrome. Curr Opin Ophthalmol. 2019;30(6):462-6.","DOI":"10.1097\/icu.0000000000000611"}],"container-title":["Clinical Practice and Cases in Emergency Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T20:52:14Z","timestamp":1605819134000},"score":1,"resource":{"primary":{"URL":"https:\/\/escholarship.org\/uc\/item\/26t9f5mg"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,9]]},"references-count":5,"issue-title":["Clinical Practice and Cases in Emergency Medicine"],"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,11,10]]}},"URL":"https:\/\/doi.org\/10.5811\/cpcem.2020.7.48507","relation":{},"ISSN":["2474-252X","2474-252X"],"issn-type":[{"value":"2474-252X","type":"electronic"},{"value":"2474-252X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9,9]]}}}