{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T16:44:06Z","timestamp":1726505046144},"reference-count":11,"publisher":"California Digital Library (CDL)","issue":"4","license":[{"start":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T00:00:00Z","timestamp":1603065600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction: Cerebral malaria, a syndrome of altered consciousness, is a rare and severe neurologic complication resulting from Plasmodium falciparum.1 Historically, cerebral malaria has been seen more frequently in children rather than adults. To complicate the diagnosis, cerebral malaria has few specific symptoms and neurologic findings can vary with each case. \n\nCase Report: We describe a case of a 61-year-old male who returned from the Democratic Republic of Congo and presented to the emergency department with dehydration, fatigue, and intermittent confusion. He was ultimately diagnosed with cerebral malaria caused by P. falciparum. \n\nConclusion: Even with close monitoring and appropriate treatment, cerebral malaria carries a severe risk of long-term neurocognitive deficits and a high mortality rate.<\/jats:p>","DOI":"10.5811\/cpcem.2020.8.47995","type":"journal-article","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T13:30:10Z","timestamp":1605619810000},"page":"533-536","source":"Crossref","is-referenced-by-count":2,"title":["Cerebral Malaria in a Patient with Recent Travel to the Congo Presenting with Delirium: A Case Report"],"prefix":"10.5811","volume":"4","author":[{"given":"Megan","family":"Roberson","sequence":"first","affiliation":[{"name":"Vanderbilt University Medical Center, Department of Emergency Medicine, Nashville, Tennessee"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Austin","family":"Smith","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Department of Emergency Medicine, Nashville, Tennessee"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"29705","published-online":{"date-parts":[[2020,10,19]]},"reference":[{"key":"ref0","unstructured":"World Health Organization. Number of Malaria Cases. 2018. Available at: http:\/\/www.who.int\/malaria\/en\/. Accessed August 4, 2018."},{"key":"ref1","unstructured":"World Health Organization. World Malaria Report. 2019. Available at: https:\/\/www.who.int\/publications-detail\/world-malaria-report-2019. Accessed February 2, 2019."},{"key":"ref2","unstructured":"World Health Organization. Malaria in Children under Five.\u00a02018. Available at: www.who.int\/malaria\/areas\/high_risk_groups\/children\/en\/. Accessed August 4, 2018."},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Newton CR and Krishna S. Severe falciparum malaria in children: current understanding of pathophysiology and supportive treatment. Pharmacol Ther. 1998;79(1):1-53.","DOI":"10.1016\/S0163-7258(98)00008-4"},{"key":"ref4","unstructured":"World Health Organization. Severe Falciparum Malaria. 2000. Available at: https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11103309. Accessed February 21, 2019."},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Tropical Medicine and International Health. Severe Malaria.\u00a02014. Available at: https:\/\/www.who.int\/malaria\/publications\/atoz\/who-severe-malaria-tmih-supplement-2014.pdf?ua=1. Accessed February 21, 2019.","DOI":"10.1111\/tmi.12313_2"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Angell S and Cetron M. Health disparities among travelers visiting friends and relatives abroad. 2005. Available at: https:\/\/www-acpjournals-org.proxy.library.upenn.edu\/doi\/full\/10.7326\/0003-4819-142-1-200501040-00013?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed. Accessed June 27, 2020.","DOI":"10.7326\/0003-4819-142-1-200501040-00013"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Bauman JL, Bauernfeind RA, Hoff JV, et al. Torsade de pointes due to quinidine: observations in 31 patients. Am. Heart J. 1984;107(3):425-30.","DOI":"10.1016\/0002-8703(84)90081-4"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Phillips RE, Looareesuwan S, White NJ, et al. Hypoglycaemia and antimalarial drugs: quinidine and release of insulin.\u00a0Br Med J (Clin Res Ed). 1986;292(6531):1319-21.","DOI":"10.1136\/bmj.292.6531.1319"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Lin J, Huang X, Qin G, et al. Manual exchange transfusion for severe imported falciparum malaria: a retrospective study.\u00a0Malar J. 2018;17(1):32.","DOI":"10.1186\/s12936-018-2174-z"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Wang W, Qian H, Cao J. Stem cell therapy: a novel treatment option for cerebral malaria?\u00a0Stem Cell Res Ther. 2015;6(1):141.","DOI":"10.1186\/s13287-015-0138-6"}],"container-title":["Clinical Practice and Cases in Emergency Medicine"],"original-title":[],"deposited":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T16:04:27Z","timestamp":1605801867000},"score":1,"resource":{"primary":{"URL":"https:\/\/escholarship.org\/uc\/item\/99z5d0sh"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,19]]},"references-count":11,"issue-title":["Clinical Practice and Cases in Emergency Medicine"],"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,11,10]]}},"URL":"https:\/\/doi.org\/10.5811\/cpcem.2020.8.47995","relation":{},"ISSN":["2474-252X","2474-252X"],"issn-type":[{"type":"electronic","value":"2474-252X"},{"type":"print","value":"2474-252X"}],"subject":[],"published":{"date-parts":[[2020,10,19]]}}}