{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T04:07:57Z","timestamp":1745899677183},"reference-count":15,"publisher":"California Digital Library (CDL)","issue":"1","license":[{"start":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T00:00:00Z","timestamp":1643328000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction: A cornual pregnancy describes a rare ectopic location positioned within the myometrium next to the fallopian tube, which can be difficult to find on traditional ultrasound imaging. Given its location and the stretch within the uterine wall, cornual pregnancies can progress for weeks prior to diagnosis. Ruptures can, therefore, be catastrophic with disproportionally high maternal mortality rates compared to other ectopic pregnancies. \nCase Report: A 34-year-old female recently treated with methotrexate for ectopic pregnancy presented to the emergency department (ED) for acute onset of lower abdominal cramping without vaginal bleeding. She arrived clinically stable and quickly decompensated with witnessed syncope in the ED, prompting point-of-care ultrasound showing free fluid in the abdomen. The patient was taken for emergent surgery by obstetrics while receiving transfusion of blood products for suspected ruptured ectopic pregnancy. A fetus estimated to be 10 weeks of age was discovered in the left cornual region. Approximately two liters of intraperitoneal blood were drained without complication. \nConclusion: Cornual pregnancy is a difficult to diagnose but potentially disastrous type of ectopic pregnancy due to massive hemorrhage. Emergency clinicians should be aware of this condition given its rare occurrence but potentially catastrophic outcomes.<\/jats:p>","DOI":"10.5811\/cpcem.2021.10.54388","type":"journal-article","created":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T04:46:21Z","timestamp":1644295581000},"page":"53-56","source":"Crossref","is-referenced-by-count":2,"title":["A Case Report of Massive Intraperitoneal Hemorrhage from Rare Cornual Pregnancy"],"prefix":"10.5811","volume":"6","author":[{"given":"Brandon","family":"Carius","sequence":"first","affiliation":[{"name":"Brian D. Allgood Army Community Hospital, Department of Emergency Medicine, Camp Humphreys, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Houston","sequence":"additional","affiliation":[{"name":"Brian D. Allgood Army Community Hospital, Department of Emergency Medicine, Camp Humphreys, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Griffith","sequence":"additional","affiliation":[{"name":"Brian D. Allgood Army Community Hospital, Department of Emergency Medicine, Camp Humphreys, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"29705","published-online":{"date-parts":[[2022,1,28]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Arleo EK and DeFilippis EM. Cornual, interstitial, and angular pregnancies: clarifying the terms and a review of the literature. Clin Imaging. 2014;38(6):763-70.","DOI":"10.1016\/j.clinimag.2014.04.002"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Malinowski A and Bates SK. Semantics and pitfalls in the diagnosis of cornual\/interstitial pregnancy. Fertil Steril. 2006;86(6):1764.e1711-64.","DOI":"10.1016\/j.fertnstert.2006.03.073"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Valsky DV and Yagel S. Ectopic pregnancies of unusual location: management dilemmas. Ultrasound Obstet Gynecol. 2008;31(3):245-51.","DOI":"10.1002\/uog.5277"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Brincat M, Bryant-Smith A, Holland TK. The diagnosis and management of interstitial ectopic pregnancies: a review. Gynecological Surgery. 2019;16(1):2.","DOI":"10.1186\/s10397-018-1054-4"},{"key":"ref4","unstructured":"Marchand G, Taher Masoud A, Sainz K, et al. A systematic review and meta-analysis of laparotomy compared with laparoscopic management of interstitial pregnancy. Facts Views Vis Obgyn. 2021;12(4):299-308."},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Ma K, Kaur N, Winters U. Cornuostomy and cornuectomy: laparoscopic management of interstitial ectopic pregnancies. J Minim Invasive Gynecol. 2020;27(7):1480-1.","DOI":"10.1016\/j.jmig.2020.04.008"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Molinaro TA and Barnhart KT. Ectopic pregnancies in unusual locations. Semin Reprod Med. 2007;25(2):123-30.","DOI":"10.1055\/s-2007-970051"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"MacRae R, Olowu O, Rizzuto MI, et al. Diagnosis and laparoscopic management of 11 consecutive cases of cornual ectopic pregnancy. Arch Gynecol Obstet. 2009;280(1):59-64.","DOI":"10.1007\/s00404-008-0872-4"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Chan LY, Fok WY, Yuen PM. Pitfalls in diagnosis of interstitial pregnancy. Acta Obstet Gynecol Scand. 2003;82(9):867-70.","DOI":"10.1034\/j.1600-0412.2003.00214.x"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"Tang A, Baartz D, Khoo SK. A medical management of interstitial ectopic pregnancy: a 5-year clinical study. Aust N Z J Obstet Gynaecol. 2006;46(2):107-11.","DOI":"10.1111\/j.1479-828x.2006.00537.x"},{"key":"ref10","unstructured":"Surekha SM, Chamaraja T, Nabakishore SN, et al. A ruptured left cornual pregnancy: a case report. J Clin Diagn Res. 2013;7(7):1455-6."},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Sargin MA, Tug N, Ayas S, et al. Is interstitial pregnancy clinically different from cornual pregnancy? A case report. J Clin Diagn Res. 2015;9(4):Qd05-06.","DOI":"10.7860\/jcdr\/2015\/12198.5836"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"Dagar M, Srivastava M, Ganguli I, et al. Interstitial and cornual ectopic pregnancy: conservative surgical and medical management. J Obstet Gynaecol India. 2018;68(6):471-6.","DOI":"10.1007\/s13224-017-1078-0"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Ackerman TE, Levi CS, Dashefsky SM, et al. Interstitial line: sonographic finding in interstitial (cornual) ectopic pregnancy. Radiology. 1993;189(1):83-7.","DOI":"10.1148\/radiology.189.1.8372223"},{"key":"ref14","unstructured":"Timor-Tritsch IE, Monteagudo A, Matera C, et al. Sonographic evolution of cornual pregnancies treated without surgery. Obstet Gynecol. 1992;79(6):1044-9."}],"container-title":["Clinical Practice and Cases in Emergency Medicine"],"original-title":[],"deposited":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T19:50:06Z","timestamp":1645818606000},"score":1,"resource":{"primary":{"URL":"https:\/\/escholarship.org\/uc\/item\/8g38b767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,28]]},"references-count":15,"issue-title":["Clinical Practice and Cases in Emergency Medicine"],"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,2,3]]}},"URL":"https:\/\/doi.org\/10.5811\/cpcem.2021.10.54388","relation":{},"ISSN":["2474-252X","2474-252X"],"issn-type":[{"type":"electronic","value":"2474-252X"},{"type":"print","value":"2474-252X"}],"subject":[],"published":{"date-parts":[[2022,1,28]]}}}