{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T07:43:24Z","timestamp":1767339804084},"reference-count":11,"publisher":"California Digital Library (CDL)","issue":"4","license":[{"start":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T00:00:00Z","timestamp":1633392000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction: Hydrogen peroxide is a common oxidizing agent that if ingested may cause injury to the gastrointestinal tract or embolic events. Although therapy is primarily supportive, gastric perforation is a rare but serious complication of corrosive ingestion that may require surgical treatment.\nCase Report: We report the case of a 77-year-old male who presented for nausea and vomiting after accidentally ingesting approximately 150 milliliters of 35% hydrogen peroxide. Computed tomography revealed gastric pneumatosis and extensive portal venous air. The patient was admitted for observation with plans for endoscopy; however, due to the limitations of our small community hospital, he was transferred to a tertiary care center due to concern for a potential gastric perforation. \nConclusion: The presence of portal venous air as a result of peroxide ingestion may be treated conservatively depending on presenting symptoms; however, severe injury such as gastrointestinal perforation may necessitate surgical intervention.<\/jats:p>","DOI":"10.5811\/cpcem.2021.6.52944","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T06:03:55Z","timestamp":1637301835000},"page":"419-421","source":"Crossref","is-referenced-by-count":3,"title":["Gastric Pneumatosis After Accidental Ingestion of Concentrated Hydrogen Peroxide: A Case Report"],"prefix":"10.5811","volume":"5","author":[{"given":"Christine","family":"Pham","sequence":"first","affiliation":[{"name":"Rancho Family Medical Group, Temecula, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Casey","family":"Graves","sequence":"additional","affiliation":[{"name":"Loma Linda University, Department of Emergency Medicine, Loma Linda, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Uttaburanont","sequence":"additional","affiliation":[{"name":"Rancho Family Medical Group, Temecula, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karan","family":"Singh","sequence":"additional","affiliation":[{"name":"Loma Linda University, Department of Emergency Medicine, Loma Linda, California; University of California, Riverside, School of Medicine, Riverside, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Witkos","sequence":"additional","affiliation":[{"name":"Loma Linda University, Department of Emergency Medicine, Loma Linda, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"29705","published-online":{"date-parts":[[2021,10,5]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Watt BE, Proudfoot AT, Vale JA. Hydrogen peroxide poisoning. Toxicol Rev. 2004;23(1):51-7.","DOI":"10.2165\/00139709-200423010-00006"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Hendriksen SM, Menth NL, Westgard BC, et al. Hyperbaric oxygen therapy for the prevention of arterial gas embolism in food grade hydrogen peroxide ingestion. Am J Emerg Med. 2017;35(5):809.e5-809.e8.","DOI":"10.1016\/j.ajem.2016.12.027"},{"key":"ref2","unstructured":"yutsis pi. oxygen therapy visionaries: a brief History of Oxygen Therapy. In: Waddell RW, ed. Oxygen to the Rescue: Oxygen Therapies and How They Help Overcome Disease, Promote Repair, and Improve Overall Function. North Bergen, NJ: Basic Health Publications Inc; 2003:15-22."},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Tohda G, Sugawa C, Gayer C, et al. Clinical evaluation and management of caustic injury in the upper gastrointestinal tract in 95 adult patients in an urban medical center. Surg Endosc. 2008;22(4):1119-25.","DOI":"10.1007\/s00464-007-9620-2"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Moon JM, Chun BJ, Min YI. Hemorrhagic gastritis and gas emboli after ingesting 3% hydrogen peroxide. J Emerg Med. 2006;30(4):403-6.","DOI":"10.1016\/j.jemermed.2005.05.036"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Hatten BW, French LK, Horowitz BZ, et al. Outcomes after high-concentration peroxide ingestions. Ann Emerg Med. 2017;69(6):726-36.e2.","DOI":"10.1016\/j.annemergmed.2016.11.022"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Vander Heide SJ and Seamon JP. Resolution of delayed altered mental status associated with hydrogen peroxide ingestion following hyperbaric oxygen therapy. Acad Emerg Med. 2003;10(9):998-1000.","DOI":"10.1197\/s1069-6563(03)00320-8"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Rider SP, Jackson SB, Rusyniak DE. Cerebral air gas embolism from concentrated hydrogen peroxide ingestion. Clin Toxicol (Phila). 2008;46(9):815-8.","DOI":"10.1080\/15563650701725136"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Byrne B, Sherwin R, Courage C, et al. Hyperbaric oxygen therapy for systemic gas embolism after hydrogen peroxide ingestion. J Emerg Med. 2014;46(2):171-5.","DOI":"10.1016\/j.jemermed.2013.08.091"},{"key":"ref9","unstructured":"Kirby JP, Snyder J, Schuerer DJE, et al. Essentials of hyperbaric oxygen therapy: 2019 review. Mo Med. 2019;116(3):176-9."},{"key":"ref10","unstructured":"Sahni T, Singh P, John MJ. Hyperbaric oxygen therapy: current trends and applications. J Assoc Physicians India. 2003;51:280-4."}],"container-title":["Clinical Practice and Cases in Emergency Medicine"],"original-title":[],"deposited":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T06:05:52Z","timestamp":1637301952000},"score":1,"resource":{"primary":{"URL":"https:\/\/escholarship.org\/uc\/item\/0nw4z2rp"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,5]]},"references-count":11,"issue-title":["Clinical Practice and Cases in Emergency Medicine"],"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,11,10]]}},"URL":"https:\/\/doi.org\/10.5811\/cpcem.2021.6.52944","relation":{},"ISSN":["2474-252X","2474-252X"],"issn-type":[{"type":"electronic","value":"2474-252X"},{"type":"print","value":"2474-252X"}],"subject":[],"published":{"date-parts":[[2021,10,5]]}}}