{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T09:24:25Z","timestamp":1759483465564},"reference-count":15,"publisher":"California Digital Library (CDL)","issue":"1","license":[{"start":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T00:00:00Z","timestamp":1641254400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction: Abdominal compartment syndrome (ACS) is a rare condition in which increased intra-abdominal pressure causes multiorgan dysfunction through decreased perfusion. Causes of this condition are variable, and early recognition is critical for favorable patient outcomes. Measurement of bladder pressure is recommended for diagnosis.\nCase Report: A 64-year-old female on clozapine with a two-year history of chronic constipation presented to the emergency department in extremis with a protuberant abdomen. After resuscitative measures, computed tomography showed a dilated, stool-filled colon with a decompressed inferior vena cava and decreased perfusion. She died despite surgical decompression. \nConclusion: Severe constipation is a rare cause of ACS, and there is a lack of evidence-based guidelines. Options for bedside decompression are limited. To reduce morbidity and mortality in this population, early recognition of ACS is imperative. Initial interventions should support hemodynamics and respiration. Definitive management is surgical decompression.<\/jats:p>","DOI":"10.5811\/cpcem.2021.7.53295","type":"journal-article","created":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T04:45:56Z","timestamp":1644295556000},"page":"20-24","source":"Crossref","is-referenced-by-count":4,"title":["Fatal Abdominal Compartment Syndrome Due to Constipation: A Case Report"],"prefix":"10.5811","volume":"6","author":[{"given":"Matthew","family":"Kongkatong","sequence":"first","affiliation":[{"name":"University of Virginia Medical Center, Department of Emergency Medicine, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malav","family":"Patel","sequence":"additional","affiliation":[{"name":"University of Virginia Medical Center, Department of Emergency Medicine, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Thom","sequence":"additional","affiliation":[{"name":"University of Virginia Medical Center, Department of Emergency Medicine, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Moak","sequence":"additional","affiliation":[{"name":"University of Virginia Medical Center, Department of Emergency Medicine, Charlottesville, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"29705","published-online":{"date-parts":[[2022,1,4]]},"reference":[{"key":"ref0","unstructured":"Maffongelli A, Fazzotta S, Palumbo VD, et al. Abdominal compartment syndrome: diagnostic evaluation and possible treatment. Clin Ter. 2020;171(2):e156-e60."},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Siebert M, Le Fouler A, Sitbon N, et al. Management of abdominal compartment syndrome in acute pancreatitis. J Visc Surg. 2021. In press.","DOI":"10.1016\/j.jviscsurg.2021.01.001"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Sosa G, Gandham N, Landeras V, et al. Abdominal compartment syndrome. Dis Mon. 2019;65(1):5-19.","DOI":"10.1016\/j.disamonth.2018.04.003"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Kirkpatrick AW, Roberts DJ, De Waele J, et al. Pediatric Guidelines Sub-Committee for the World Society of the Abdominal Compartment Syndrome. Intensive Care Med. 2013;39(7):1190-206.","DOI":"10.1007\/s00134-013-2906-z"},{"key":"ref4","unstructured":"Rao S. Constipation in the older adult. In: UpToDate, Talley N, Schmader K, Grover S (Eds), UpToDate, Waltham, MA."},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Rao P, Chaudhry R, Kumar S. Abdominal compartment pressure monitoring \u2013 a simple technique. Med J Armed Forces India. 2006;62(3):269-70.","DOI":"10.1016\/s0377-1237(06)80017-1"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Chiapponi C, Stoker U, Korner M, et al. Emergency percutaneous needle decompression for tension pneumoperitoneum. BMC Gastroenterol. 2011;11:48.","DOI":"10.1186\/1471-230x-11-48"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Starnes S, Lawrence H, Navaratnam R. Is constipation a trivial matter? BMJ Case Rep. 2016;2016.","DOI":"10.1136\/bcr-2015-213085"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Jambet S, Guiu B, Olive-Abergel P, et al. Psychiatric drug-induced fatal abdominal compartment syndrome. Am J Emerg Med. 2012;30(3):513.e5-7.","DOI":"10.1016\/j.ajem.2011.01.005"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Bachman C, Aagaard L, Bernardo M, et al. International trends in clozapine use: a study of 17 countries. Acta Psychiatr Scand. 2017;136(1):37-51.","DOI":"10.1111\/acps.12742"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Shirazi A, Stubbs B, Gomez L, et al. Prevalence and predictors of clozapine-associated constipation: a systematic review and meta-analysis. Int J Mol Sci. 2016;17(6):863.","DOI":"10.3390\/ijms17060863"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Every-Palmer S and Ellis P. Clozapine-Induced gastrointestinal hypomotility: a 22 year bi-national pharmacovigilance study of serious or fatal \u2018slow gut\u2019 reaction and comparison with international drug safety advice. CNS Drugs. 2017;31(8):699-709.","DOI":"10.1007\/s40263-017-0448-6"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Lexicomp. Risperidone: Drug information. 2011. Available at: https:\/\/somepomed.org\/articulos\/contents\/mobipreview.htm?18\/16\/18689?source=see_link. Accessed April 11, 2021.","DOI":"10.1016\/S1359-6446(11)00269-8"},{"key":"ref13","unstructured":"Lexicomp. Glycopyrrolate (glycopyrronium) (systemic): Drug Information. 2011. Available at: https:\/\/www.uptodate.com\/contents\/glycopyrrolate-glycopyrronium-pediatric-drug-information. Accessed May 17, 2021."},{"key":"ref14","unstructured":"Lexicomp. Benztropine (benzatropine): Drug information. 2011. Available at: https:\/\/somepomed.org\/articulos\/contents\/mobipreview.htm?7\/51\/7998?source=see_link. Accessed May 17, 2021."}],"container-title":["Clinical Practice and Cases in Emergency Medicine"],"original-title":[],"deposited":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T19:49:35Z","timestamp":1645818575000},"score":1,"resource":{"primary":{"URL":"https:\/\/escholarship.org\/uc\/item\/8mb5z8x2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,4]]},"references-count":15,"issue-title":["Clinical Practice and Cases in Emergency Medicine"],"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,2,3]]}},"URL":"https:\/\/doi.org\/10.5811\/cpcem.2021.7.53295","relation":{},"ISSN":["2474-252X","2474-252X"],"issn-type":[{"type":"electronic","value":"2474-252X"},{"type":"print","value":"2474-252X"}],"subject":[],"published":{"date-parts":[[2022,1,4]]}}}