{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T19:31:04Z","timestamp":1762025464449,"version":"build-2065373602"},"reference-count":0,"publisher":"California Digital Library (CDL)","issue":"4","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Practice and Cases in Emergency Medicine"],"abstract":"<p>Introduction: Determining a mother\u2019s Rhesus (Rh) antigen status is a critical component of prenatal care, guiding the administration of Rh immunoglobulin (Rh Ig) to prevent Rh alloimmunization, a condition that can lead to hemolytic disease of the newborn (HDN). HDN is a blood disorder where the blood types of a mother and fetus are incompatible and causes hemolysis of the fetus\u2019 erythrocytes, a major cause of fetal death. Rh Ig is commonly administered to Rh-negative (Rh-) women as a prophylactic measure. However, categorizing a patient\u2019s Rh status is not always straightforward as individuals can exhibit \u201cweakly Rh+\u201d or \u201cformerly Rh+\u201d phenotypes, complicating clinical management. Case Report: This is a case of a 28-year-old Gravida three Para two (G3P2) woman whose Rh status has varied across multiple pregnancies, who presented to the emergency department with an active miscarriage requesting a dose of Rh Ig. Her blood typing indicated O+ status, which conflicted with her previous history of being O-. Conclusion: Most women in the United States are Rh-positive (Rh+), which eliminates the need for Rh Ig during pregnancy. Nevertheless, there are approximately 550,000 women annually who are categorized as Rh-, and 16,700 of these cases may represent weak Rh positivity. Identifying weakly Rh+ individuals holds potential to reallocate scarce Rh Ig resources to those who require them. This report explores the clinical implications of weak Rh positivity, emphasizing maternal-fetal health considerations and the nuanced approach required to manage such cases effectively in the emergency department.<\/p>","DOI":"10.5811\/cpcem.47264","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T04:08:35Z","timestamp":1758686915000},"source":"Crossref","is-referenced-by-count":0,"title":["The Complexity of Weak Rhesus Positivity in Pregnancy: Challenges and Management\u2014A Case Report"],"prefix":"10.5811","volume":"9","author":[{"given":"Meghan Grace","family":"Warner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Villa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordan","family":"Winebrenner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsay","family":"Tjiattas-Saleski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"29705","published-online":{"date-parts":[[2025,9,24]]},"container-title":["Clinical Practice and Cases in Emergency Medicine"],"original-title":[],"link":[{"URL":"https:\/\/escholarship.org\/content\/qt3790h51q\/qt3790h51q.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T19:26:29Z","timestamp":1762025189000},"score":1,"resource":{"primary":{"URL":"https:\/\/escholarship.org\/uc\/item\/3790h51q"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,24]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,10,24]]}},"URL":"https:\/\/doi.org\/10.5811\/cpcem.47264","relation":{},"ISSN":["2474-252X"],"issn-type":[{"type":"electronic","value":"2474-252X"}],"subject":[],"published":{"date-parts":[[2025,9,24]]}}}