{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T03:19:31Z","timestamp":1776309571832,"version":"3.50.1"},"reference-count":0,"publisher":"California Digital Library (CDL)","issue":"5","license":[{"start":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T00:00:00Z","timestamp":1723766400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Western Journal of Emergency Medicine"],"abstract":"<p>Background: The prognostic value of body temperature in sepsis-induced coagulopathy (SIC) remains unclear. In this study we aimed to investigate the association between temperature and mortality among SIC patients. Methods: We analyzed data for 9,860 SIC patients from an intensive care database. Patients were categorized by maximum temperature in the \ufb01rst 24 hours into the following: \u226436.0\u00b0C; 36.0\u201337.0\u00b0C; 37.0\u201338.0\u00b0C; 38.0\u201339.0\u00b0C; and \u226539.0\u00b0C. The primary outcome was 28-day mortality. We used multivariate regression to analyze the temperature-mortality association. Results: The 37.0\u201338.0\u00b0C, 38.0\u201339.0\u00b0C and \u226539.0\u00b0C groups correlated with lower 28-day mortality (adjusted HR 0.70, 0.76 and 0.72, respectively), while the &amp;lt;36.0\u00b0C group correlated with higher mortality compared to the 36.0\u201337.0\u00b0C group (adjusted HR 2.60). A nonlinear relationship was observed between temperature and mortality. Subgroup analysis found no effect modi\ufb01cation except in cerebrovascular disease. Conclusion: A body temperature in the range of 37.0\u201338.0\u00b0C was associated with a signi\ufb01cantly lower mortality compared to the normal temperature (36.0\u201337.0\u00b0C) group. Additionally, a gradual but statistically insigni\ufb01cant increase in mortality risk was observed when body temperature exceeded 38.0\u00b0C. Further research should validate these \ufb01ndings and elucidate involved mechanisms, especially in cerebrovascular disease subgroups.<\/p>","DOI":"10.5811\/westjem.18589","type":"journal-article","created":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T14:50:55Z","timestamp":1723819855000},"source":"Crossref","is-referenced-by-count":2,"title":["The Nonlinear Relationship Between Temperature and Prognosis in Sepsis-induced Coagulopathy Patients: A Retrospective Cohort Study from MIMIC-IV Database"],"prefix":"10.5811","volume":"25","author":[{"given":"Guojun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianen","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingtao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiaohua","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weigan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"29705","published-online":{"date-parts":[[2024,8,16]]},"container-title":["Western Journal of Emergency Medicine"],"original-title":[],"link":[{"URL":"https:\/\/escholarship.org\/content\/qt2pd307kp\/qt2pd307kp.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T19:37:39Z","timestamp":1726688259000},"score":1,"resource":{"primary":{"URL":"https:\/\/escholarship.org\/uc\/item\/2pd307kp"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,16]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,9,18]]}},"URL":"https:\/\/doi.org\/10.5811\/westjem.18589","relation":{},"ISSN":["1936-9018"],"issn-type":[{"value":"1936-9018","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,16]]}}}