{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T18:48:57Z","timestamp":1785696537980,"version":"3.56.0"},"reference-count":26,"publisher":"Brieflands","issue":"2","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["brieflands.com"],"crossmark-restriction":false},"short-container-title":["Anesth Pain Med"],"abstract":"<jats:p>Background: Children undergoing adenotonsillectomy often have partial airway obstruction due to hypertrophic tonsils and adenoids, increasing their risk of oxygen desaturation during anesthesia induction. Objectives: This study aimed to evaluate whether apneic oxygenation via nasal cannula prevents oxygen desaturation during tracheal intubation in children aged 3 - 10 years undergoing adenotonsillectomy while assessing its effects on intubation conditions and hemodynamic stability. Methods: In this prospective, single-blinded, randomized controlled trial, 140 children scheduled for adenotonsillectomy were allocated to either standard intubation (group A, n = 70) or apneic oxygenation (group B, n = 70; 0.2 L\/kg\/min via nasal cannula). The primary outcome was the lowest peripheral oxygen saturation (SpO\u2082) during intubation. Results: Peripheral SpO\u2082 was significantly lower during intubation in group A (97.40 \u00b1 2.96) than in group B (99.91 \u00b1 0.28) (P &lt; 0.001). Group B also maintained significantly higher SpO\u2082 immediately after intubation (99.91 \u00b1 0.28%) than group A (97.77 \u00b1 2.24%; P &lt; 0.001). No episodes of desaturation occurred in group B during the procedure (P &lt; 0.001). In group A, 21.43% of patients desaturated to \u2264 95% (P &lt; 0.001). Severe desaturation (SpO\u2082 &lt; 92%) occurred in 7.14% of controls but was absent in group B (P = 0.023). Intubation time, intubation attempts, and bradycardia rates were comparable between groups (P &gt; 0.05). Conclusions: Apneic oxygenation during intubation in children undergoing adenotonsillectomy effectively prevented desaturation without compromising safety or procedural efficiency<\/jats:p>","DOI":"10.5812\/aapm-169980","type":"journal-article","created":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T18:31:12Z","timestamp":1785695472000},"update-policy":"https:\/\/doi.org\/10.5812\/crossmark_update_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of Apneic Oxygenation During Induction of General Anesthesia in Children Undergoing Adenotonsillectomy: A Prospective Randomized Controlled Study"],"prefix":"10.5812","volume":"16","author":[{"given":"Safaa Gaber","family":"Ragab","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Ali Lotfy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph 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