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Methods: In this randomized clinical trial study, 60 patients aged 18 - 60 years old, according to the American Society of Anesthesiology (ASA) I - II, who underwent spinal canal stenosis or scoliosis surgery, were divided into two groups. In the control group, patients received 0.07 - 0.1 \u00b5g\/kg\/h intraoperative Fentanyl infusion, and in the intervention group 0.1 - 0.2 \u00b5g\/kg\/min remifentanil was infused during the surgery. Both groups received 15 mg\/kg intravenous Acetaminophen 20 minutes before the end of the surgery. Postoperative pain score and morphine consumption were measured 6, 12, 24, and 48 hours after discharge from the post-anesthesia care unit (PACU). Results: During the first 12 hours, VAS and morphine consumption were significantly higher in remifentanil group (P &lt; 0.001). However, no significant difference was found between the two groups in morphine consumption 12 - 48 hours after surgery. Conclusions: These findings suggest that Remifentanil infusion during surgery may increase postoperative pain. Also, VAS and morphine consumption were higher during the first 12 hours.<\/jats:p>","DOI":"10.5812\/aapm.115576","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T09:04:02Z","timestamp":1632215042000},"update-policy":"https:\/\/doi.org\/10.5812\/crossmark_update_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparison of Intraoperative Infusion of Remifentanil Versus Fentanyl on Pain Management in Patients Undergoing Spine Surgery: A Double Blinded Randomized Clinical Trial"],"prefix":"10.5812","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3398-896X","authenticated-orcid":false,"given":"Reza","family":"Shariat 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