{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T01:14:38Z","timestamp":1779930878905,"version":"3.53.1"},"reference-count":0,"publisher":"Mattioli1885","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Pract Concept"],"abstract":"<jats:p>Background: Cutaneous horns usually develop on a keratinocytic base with the histopathology on a spectrum ranging from benign keratosis through to invasive squamous cell carcinoma (SCC). Some features of horns are easily identified using dermatoscopy.\r\nObjective: To investigate if specific clinical or dermatoscopy features of horns correlate with the histopathology in the base of the horn.\r\nMethods: Consecutive horn cases (n=163) were assessed prospectively in vivo for horn height, terrace morphology and base erythema using a Heine Delta 20 dermatoscope. Cases with potentially confounding influences were excluded. A history of horn pain or pain on palpation was also recorded.\r\nResults: Benign keratosis (n = 49), actinic keratosis (n = 21), SCC in situ (n = 37) and invasive SCC (n = 56) were recorded. An invasive SCC presenting as a horn as most likely to have a height less than the base diameter, 66% (37\/56). Compared to the other study entities, invasive SCC tends to have less terrace morphology (P&lt;0.05), a higher incidence of base erythema (P&lt;0.05) and more pain (P&lt;0.01).\r\nLimitations: Data categories did not include anatomic site or horn growth rates. Excision selection bias favored the incidence of invasive SCC.\r\nConclusions: Horns presenting on an invasive SCC base are more likely to have a height less than the diameter of the base, not to have terrace morphology, to have an erythematous base and to be painful.<\/jats:p>","DOI":"10.5826\/dpc.0302a02","type":"journal-article","created":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T18:27:40Z","timestamp":1367432860000},"page":"3-7","source":"Crossref","is-referenced-by-count":30,"title":["Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base"],"prefix":"10.5826","author":[{"given":"John","family":"Pyne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devendra","family":"Sapkota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian Cheng","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27750","published-online":{"date-parts":[[2013,4,30]]},"container-title":["Dermatology Practical &amp; Conceptual"],"original-title":[],"link":[{"URL":"https:\/\/dpcj.org\/index.php\/dpc\/article\/download\/dermatol-pract-concept-articleid-dp0302a02\/dermatol-pract-concept-articleid-dp0302a02-pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dpcj.org\/index.php\/dpc\/article\/download\/dermatol-pract-concept-articleid-dp0302a02\/dermatol-pract-concept-articleid-dp0302a02-pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T13:40:26Z","timestamp":1708436426000},"score":1,"resource":{"primary":{"URL":"https:\/\/dpcj.org\/index.php\/dpc\/article\/view\/dermatol-pract-concept-articleid-dp0302a02"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.5826\/dpc.0302a02","relation":{},"ISSN":["2160-9381"],"issn-type":[{"value":"2160-9381","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,30]]}}}