{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T00:20:19Z","timestamp":1793665219632,"version":"4.5.1"},"reference-count":12,"publisher":"Mattioli1885","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction: Psoriasis is a common skin disease displaying a broad spectrum of clinical presentations that can sometimes pose diagnostic challenges. UV-induced fluorescence dermatoscopy (UVFD) is a novel dermatoscopy mode useful as a complementary diagnostic method in inflammatory dermatoses. The understanding of red fluorescence in psoriasis, caused by protoporphyrin IX, in regard to clinical-morphological features, site-dependency, geographic variability, and bleaching with sun-exposure remains very limited. Objective: The study objective was to explore fluorescence patterns in relation to demographic and geographic factors, disease subtype, lesion morphology, Psoriasis Area and Severity Index (PASI) score, seasonal variations, and bathing practices. Method: This study included 356 UVFD images from 111 psoriatic patients naive to the treatment from Central and Southern Europe and explored fluorescence patterns in relation to demographic and geographic factors, disease subtype, lesion morphology, Psoriasis Area and Severity Index (PASI) score, seasonal variations, and bathing practices. For the statistical analysis we have employed a series of Chi-squared tests for independence and independent samples t-tests. Results: Red fluorescence was predominantly observed in subtypes affecting sun-protected areas in patients with higher PASI scores, especially erythema and induration. Geographic and seasonal variability was observed, while age, sex, and bathing practices did not significantly affect fluorescence patterns. Conclusion: The study confirms that red fluorescence in psoriatic lesions under UVFD is suppressed by sun exposure and correlates with disease severity.<\/jats:p>","DOI":"10.5826\/dpc.1502a5466","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T10:28:41Z","timestamp":1744367321000},"page":"5466","source":"Crossref","is-referenced-by-count":4,"title":["Ultraviolet-induced Fluorescence Patterns in Psoriasis: Insights from a Large International Cohort Study"],"prefix":"10.5826","volume":"15","author":[{"given":"Pawel","family":"Pietkiewicz","sequence":"first","affiliation":[{"name":"Centrum Medyczne Zwierzyniecka, Pozna\u0144, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Salwowska","sequence":"first","affiliation":[{"name":"Department of Dermatology, School of Medicine, Medical University of Silesia, Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todorovska","family":"Verche","sequence":"first","affiliation":[{"name":"Dermatology Private Practice, Skopje, North Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marian","family":"Voloshynovych","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falkowski","family":"Pawe\u0142","sequence":"first","affiliation":[{"name":"Department of Family Medicine, Medical University of Bia\u0142ystok, Bia\u0142ystok, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Giedziun","sequence":"first","affiliation":[{"name":"Faculty of Information and Communication Technology, Wroc\u0142aw University of Science and Technology, Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Navarrete-Dechent","sequence":"first","affiliation":[{"name":"Melanoma and Skin Cancer Unit, Escuela de Medicina, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adarsha","family":"Adhikari","sequence":"first","affiliation":[{"name":"Medical Private Practice, Pokhara, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora","family":"Pollozhani","sequence":"first","affiliation":[{"name":"University Clinic of Dermatology, Ss Cyril and Methodius University of Skopje, Skopje, North Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enzo","family":"Errichetti","sequence":"first","affiliation":[{"name":"Institute of Dermatology, Department of Medicine, University of Udine, Udine, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27750","published-online":{"date-parts":[[2025,4,11]]},"reference":[{"key":"10.5826\/dpc.1502a5466_ref1","doi-asserted-by":"crossref","unstructured":"Lallas A, Errichetti E, Ioannides D. Dermoscopy in General Dermatology. CRC Press; 2018.","DOI":"10.1201\/9781315201733"},{"key":"10.5826\/dpc.1502a5466_ref2","doi-asserted-by":"crossref","unstructured":"Errichetti E. Dermoscopy of inflammatory dermatoses (inflammoscopy): an up-to-date overview. Dermatol Pract Concept. 2019;9(3):169\u201380. DOI: 10.5826\/dpc.0903a01.","DOI":"10.5826\/dpc.0903a01"},{"key":"10.5826\/dpc.1502a5466_ref3","doi-asserted-by":"crossref","unstructured":"Errichetti E. Dermoscopy in monitoring and predicting therapeutic response in general dermatology (non-tumoral dermatoses): an up-to-date overview. Dermatol Ther (Heidelb). 2020;10(6):1199\u2013214. DOI: 10.1007\/s13555-020-00455-y.","DOI":"10.1007\/s13555-020-00455-y"},{"key":"10.5826\/dpc.1502a5466_ref4","doi-asserted-by":"crossref","unstructured":"Pietkiewicz P, Navarrete-Dechent C, Togawa Y, et al. Applications of ultraviolet and sub-ultraviolet dermatoscopy in neoplastic and non-neoplastic dermatoses: a systematic review. Dermatol Ther (Heidelb). 2024;14(2):361\u2013390. DOI: 10.1007\/s13555-024-01104-4.","DOI":"10.1007\/s13555-024-01104-4"},{"key":"10.5826\/dpc.1502a5466_ref5","doi-asserted-by":"crossref","unstructured":"Errichetti E, Pietkiewicz P, Bhat YJ, et al. Diagnostic accuracy of ultraviolet-induced fluorescence dermoscopy in non-neoplastic dermatoses (general dermatology): a multicentric retrospective comparative study. J Eur Acad Dermatol Venereol. 2024;39(1):97\u2013108. DOI: 10.1111\/jdv.19795.","DOI":"10.1111\/jdv.19795"},{"key":"10.5826\/dpc.1502a5466_ref6","doi-asserted-by":"crossref","unstructured":"Navarrete-Dechent C, Pietkiewicz P, Astronave G, et al. The role of ultraviolet induced fluorescence dermatoscopy for the detection of multiple aggregated yellow-white (MAY) globules in basal cell carcinoma. J Am Acad Dermatol. 2024;91(6):1250\u20131252. 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