{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T05:19:24Z","timestamp":1769836764824,"version":"3.49.0"},"reference-count":24,"publisher":"Mattioli1885","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction: Demodex mites reside in the hair follicles and sebaceous glands of the head and face. An increase in their population can lead to primary or secondary demodicosis. Septorhinoplasty is a frequently performed aesthetic surgical procedure that can cause various cutaneous complications in the facial area. Objectives: This study aimed to investigate the density of Demodex mites and the prevalence of demodicosis following septorhinoplasty. Methods: A total of 40 patients (29 females, 11 males) scheduled for septorhinoplasty, with a mean age of 26.25\u00b17.47 years, were evaluated for clinical findings of demodicosis before and at the third month after surgery. Demodex density was assessed using the standardized skin surface biopsy technique, a noninvasive method involving cyanoacrylate adhesive, and microscopic evaluation of samples taken from the bilateral cheeks and nose. Results: A statistically significant increase was observed in the number of Demodex mites in the malar and nasal regions and in the prevalence of demodicosis following septorhinoplasty. Additionally, the frequency of seborrhea and pustules showed a significant rise. Symptoms related to demodicosis were found to appear around the 22nd postoperative day and persisted up to the third month. Conclusions: Demodicosis should be considered in the differential diagnosis of patients presenting with erythema, papules, and pustules in both the early and late postoperative periods following septorhinoplasty, and necessary diagnostic investigations should be performed. Further large-scale studies with a greater number of patients are required to support our findings.<\/jats:p>","DOI":"10.5826\/dpc.1601a6113","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T15:40:15Z","timestamp":1769787615000},"page":"6113","source":"Crossref","is-referenced-by-count":0,"title":["Increased Demodex Density and Risk of Demodicosis After Septorhinoplasty: A Prospective Cohort Study"],"prefix":"10.5826","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7886-1060","authenticated-orcid":false,"given":"Sevgi","family":"Kulakl\u0131","sequence":"first","affiliation":[{"name":"Giresun University, Faculty of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8628-6107","authenticated-orcid":false,"given":"I\u015f\u0131l Deniz","family":"O\u011fuz","sequence":"first","affiliation":[{"name":"Giresun University, Faculty of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5969-4321","authenticated-orcid":false,"given":"Yonca","family":"\u00c7oluk","sequence":"first","affiliation":[{"name":"Giresun University, Faculty of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27750","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"10.5826\/dpc.1601a6113_ref1","doi-asserted-by":"crossref","unstructured":"Erdal B, Albayrak H. Investigation of the Prevalence of Demodex spp. in Dermatological Diseases. Turkiye Parazitol Derg. 2022;46(1):54-59. DOI:10.4274\/tpd.galenos.2021.93685 PMID: 35232707","DOI":"10.4274\/tpd.galenos.2021.93685"},{"key":"10.5826\/dpc.1601a6113_ref2","doi-asserted-by":"crossref","unstructured":"Chen W, Plewig G. Human demodicosis: revisit and a proposed classification. Br J Dermatol. 2014;170(6):1219-1225. DOI:10.1111\/bjd.12850 PMID: 24471456","DOI":"10.1111\/bjd.12850"},{"key":"10.5826\/dpc.1601a6113_ref3","doi-asserted-by":"crossref","unstructured":"Akba\u015f Karabay E, Aksu \u00c7erman A. Demodex folliculorum infestations in common facial dermatoses: acne vulgaris, rosacea, seborrheic dermatitis. An Bras Dermatol 2020;95:187-193. DOI:10.1016\/j.abd.2019.08.023 PMID: 32113677","DOI":"10.1016\/j.abd.2019.08.023"},{"key":"10.5826\/dpc.1601a6113_ref4","doi-asserted-by":"crossref","unstructured":"Forton FMN, De Maertelaer V. Which factors influence Demodex proliferation? A retrospective pilot study highlighting a possible role of subtle immune variations and sebaceous gland status. J Dermatol 2021; 48: 1210-20. DOI:10.1111\/1346-8138.15910 PMID: 33969532","DOI":"10.1111\/1346-8138.15910"},{"key":"10.5826\/dpc.1601a6113_ref5","doi-asserted-by":"crossref","unstructured":"Koc EA, Buyuklu F, Ko\u00e7 B, Demirci GT. Skin problems following septorhinoplasty. Laryngoscope. 2015;125:1291-5. DOI:10.1002\/lary.25073 PMID: 25476595","DOI":"10.1002\/lary.25073"},{"key":"10.5826\/dpc.1601a6113_ref6","doi-asserted-by":"crossref","unstructured":"Erdur ZB, \u00d6ktem F, \u0130nci E, Yener HM, G\u00f6zen ED, Birben A\u00d6, et al. Effect of Nasal Skin Type on Skin Problems following Rhinoplasty. Facial Plast Surg. 2020;36:643-649. DOI:10.1055\/s-0040-1713792 PMID: 32717761","DOI":"10.1055\/s-0040-1713792"},{"key":"10.5826\/dpc.1601a6113_ref7","unstructured":"Nemati S, Golchay J, Alizadeh A. 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