{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T05:36:55Z","timestamp":1777873015237,"version":"3.51.4"},"reference-count":19,"publisher":"Mattioli1885","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction: Psoriasis has a profound impact on patients\u2019 quality of life, affecting their emotional well-being, social interactions, and career choices. However, current assessment tools fail to capture the long-term burden of psoriasis. Objective: The aim of this study was to develop the CORONATE questionnaire, designed to assess the lifelong impact of moderate-to-severe psoriasis on patients' lives. Methods: A multicenter cross-sectional study was conducted in 15 Italian dermatology centers. This study included 300 patients (age \u226530 years) diagnosed with moderate-to-severe psoriasis (PASI \u226510 or PASI &lt;10 with involvement of sensitive areas). The CORONATE questionnaire, initially consisting of 25 items, was refined through factor analysis. Exploratory and confirmatory factor analyses were performed. Results: The final questionnaire included 18 items grouped into two dimensions: \"Work Issues\" (5 items) and \"Psychosocial Life\" (13 items). Factor analysis confirmed strong internal consistency (Cronbach\u2019s alpha: Work Issues = 0.81; Psychosocial Life = 0.91). The model showed excellent fit indices (\u03c7\u00b2 (153) = 6956.471, P&lt;0.001; Comparative Fit Index = 0.998; Tucker-Lewis Index = 0.998; Standardized Root Mean Square Residual = 0.053). Conclusion: The CORONATE questionnaire is a reliable tool for assessing the cumulative burden of psoriasis. Its implementation in clinical practice may improve personalized patient care.<\/jats:p>","DOI":"10.5826\/dpc.1602a7073","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:48:38Z","timestamp":1777571318000},"page":"7073","source":"Crossref","is-referenced-by-count":0,"title":["CORONATE: A Novel Questionnaire to Assess the Long-Term Impact of Psoriasis on Patients\u2019 Lives"],"prefix":"10.5826","volume":"16","author":[{"given":"Stefano","family":"Piaserico","sequence":"first","affiliation":[{"name":"Dermatology Unit, Department of Medicine, DIMED, Universit\u00e0 di Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Sampogna","sequence":"additional","affiliation":[{"name":"Istituto Dermopatico dell'Immacolata (IDI)-IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Accorinti","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Dermatology Clinic, University of Turin, Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Amerio","sequence":"additional","affiliation":[{"name":"Department of Medicine and Aging Science, University of Chieti-Pescara, Chieti, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Bonifati","sequence":"additional","affiliation":[{"name":"San Gallicano Dermatological Institute, IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra M.G.","family":"Brunasso","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine-Dermatology, Villa Scassi Hospital-ASL3, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Burlando","sequence":"additional","affiliation":[{"name":"Clinica Dermatologica \u2013 DISSAL, Ospedale Policlinico San Martino-IRCCS Universit\u00e0 di Genova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Ciolfi","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medicine, DIMED, Universit\u00e0 di Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Conti","sequence":"additional","affiliation":[{"name":"Department of Surgery, Dermatology Unit, Infermi Hospital, Rimini, AUSL Romagna, Rimini, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Di Fino","sequence":"additional","affiliation":[{"name":"AbbVie srl, Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Esposito","sequence":"additional","affiliation":[{"name":"Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila, L\u2019Aquila, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gennaro Marco","family":"Falco","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Translational Medicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy; Dermatology Unit, Policlinico A. Gemelli, IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Concetta","family":"Fargnoli","sequence":"additional","affiliation":[{"name":"Department of Biotechnological and Applied Clinical Sciences, University of L\u2019Aquila, L\u2019Aquila, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Foti","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari, Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Gisondi","sequence":"additional","affiliation":[{"name":"Section of Dermatology and Venereology Department of Medicine, University of Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Graceffa","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Dermatology, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Guarneri","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Dermatology, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marika","family":"Iarrera","sequence":"additional","affiliation":[{"name":"Dermatologic Unit, Infermi Hospital Rimini, AUSL Romagna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Loconsole","sequence":"additional","affiliation":[{"name":"Azienda Ospedaliera Universitaria Policlinico Consorziale Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Levi","sequence":"additional","affiliation":[{"name":"AbbVie srl, Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"Lozito","sequence":"additional","affiliation":[{"name":"Section of Dermatology and Venereology Department of Medicine, University of Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daria","family":"Nucciarelli","sequence":"additional","affiliation":[{"name":"AbbVie srl, Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Nunziati","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Section of dermatology, University of Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Maria","family":"Offidani","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Sciences, Dermatology Unit Polytechnic Marche, Universit\u00e0, Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora","family":"Parodi","sequence":"additional","affiliation":[{"name":"Clinica Dermatologica \u2013 DISSAL, Ospedale Policlinico San Martino-IRCCS Universit\u00e0 di Genova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Perini","sequence":"additional","affiliation":[{"name":"UOC Dermatology, Department of Medicine and Surgery, University of Parma, Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Peterle","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Prignano","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Section of dermatology, University of Florence, 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