{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,3,17]],"date-time":"2023-03-17T04:40:35Z","timestamp":1679028035321},"reference-count":0,"publisher":"The Medical Letter, Inc.","issue":"1671","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Lett Drugs Ther"],"abstract":"<jats:p>Three products are currently available in the US for treatment of high-risk (see Table 1),1 nonhospitalized adults with mild to moderate COVID-19: oral ritonavir-boosted nirmatrelvir (Paxlovid), IV remdesivir (Veklury), and oral molnupiravir (Lagevrio). Remdesivir is FDA-approved for such use; nirmatrelvir\/ritonavir and molnupiravir are available under an FDA Emergency Use Authorization. Because the pivotal clinical trials of these products for outpatient use were conducted in patients who were not vaccinated against COVID-19, some clinicians have questioned whether they can benefit vaccinated outpatients.<\/jats:p>","DOI":"10.58347\/tml.2023.1671a","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T15:33:03Z","timestamp":1678980783000},"page":"33-34","source":"Crossref","is-referenced-by-count":0,"title":["Antiviral Drugs for COVID-19 in Vaccinated Outpatients"],"prefix":"10.58347","volume":"65","author":[{"name":"Editors from The Medical Letter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"37151","published-online":{"date-parts":[[2023,3,6]]},"container-title":["The Medical Letter on Drugs and Therapeutics"],"original-title":[],"deposited":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T15:33:03Z","timestamp":1678980783000},"score":1,"resource":{"primary":{"URL":"https:\/\/secure.medicalletter.org\/TML-article-1671a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,6]]},"references-count":0,"journal-issue":{"issue":"1671","published-online":{"date-parts":[[2023,3,6]]}},"URL":"https:\/\/doi.org\/10.58347\/tml.2023.1671a","relation":{},"ISSN":["1523-2859"],"issn-type":[{"value":"1523-2859","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,6]]}}}