{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:12:47Z","timestamp":1790611967153,"version":"4.1.0"},"reference-count":0,"publisher":"The Medical Letter, Inc.","issue":"1683","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Lett Drugs Ther"],"abstract":"<jats:p>Lecanemab-irmb (Leqembi \u2013 Eisai\/Biogen), the IV amyloid-directed monoclonal antibody that received accelerated approval from the FDA in January 2023 for treatment of early Alzheimer\u2019s disease, has now received full approval from the FDA based on a trial showing that it slowed cognitive and functional decline in patients with mild cognitive impairment (MCI) or mild Alzheimer\u2019s disease dementia and confirmed presence of brain amyloid.<\/jats:p>","DOI":"10.58347\/tml.2023.1683a","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T15:22:50Z","timestamp":1694013770000},"page":"129-130","source":"Crossref","is-referenced-by-count":4,"title":["Lecanemab (Leqembi) Granted Full Approval for Early Alzheimer's Disease"],"prefix":"10.58347","volume":"65","author":[{"name":"Editors from The Medical Letter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"37151","published-online":{"date-parts":[[2023,8,21]]},"container-title":["The Medical Letter on Drugs and Therapeutics"],"original-title":[],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T15:22:51Z","timestamp":1694013771000},"score":1,"resource":{"primary":{"URL":"https:\/\/secure.medicalletter.org\/TML-article-1683a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,21]]},"references-count":0,"journal-issue":{"issue":"1683","published-online":{"date-parts":[[2023,8,21]]}},"URL":"https:\/\/doi.org\/10.58347\/tml.2023.1683a","relation":{},"ISSN":["1523-2859"],"issn-type":[{"value":"1523-2859","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,21]]}}}