{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T15:54:03Z","timestamp":1792079643583,"version":"4.4.0"},"reference-count":0,"publisher":"The Medical Letter, Inc.","issue":"1766","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Lett Drugs Ther"],"abstract":"<jats:p>Iberdomide (Zenbexus \u2013 BMS), an oral first-in-class cereblon-modulating protein degrader, has received accelerated approval from the FDA for use in combination with the CD38-directed cytolytic antibody daratumumab (Darzalex Faspro) and dexamethasone for treatment of multiple myeloma in adults who received at least one prior line of therapy, including a proteasome inhibitor (e.g., bortezomib) and an immunomodulatory drug. The drug was approved based on a surrogate endpoint of minimal residual disease-negative complete response.<\/jats:p>","DOI":"10.58347\/tml.2026.1766e","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T15:42:16Z","timestamp":1792078936000},"page":"e175-e176","source":"Crossref","is-referenced-by-count":0,"title":["Iberdomide (Zenbexus) for Multiple Myeloma"],"prefix":"10.58347","volume":"68","member":"37151","published-online":{"date-parts":[[2026,10,26]]},"container-title":["The Medical Letter on Drugs and Therapeutics"],"original-title":[],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T15:42:16Z","timestamp":1792078936000},"score":1,"resource":{"primary":{"URL":"https:\/\/secure.medicalletter.org\/TML-article-1766e"}},"subtitle":[],"editor":[{"name":"Editors from The Medical Letter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,10,26]]},"references-count":0,"journal-issue":{"issue":"1766","published-online":{"date-parts":[[2026,10,26]]}},"URL":"https:\/\/doi.org\/10.58347\/tml.2026.1766e","relation":{},"ISSN":["1523-2859"],"issn-type":[{"value":"1523-2859","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,26]]}}}