{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:43:57Z","timestamp":1792082637440,"version":"4.4.0"},"reference-count":0,"publisher":"The Medical Letter, Inc.","issue":"1766","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Lett Drugs Ther"],"abstract":"<jats:p>Zidesamtinib (Jideytro \u2013 GSK), an oral kinase inhibitor, has been approved by the FDA for treatment of locally advanced or metastatic ROS1-positive non-small cell lung cancer (NSCLC) in adults who received at least one prior ROS1 kinase inhibitor. It is the fifth oral kinase inhibitor to be approved in the US for treatment of ROS1-positive NSCLC; crizotinib (Xalkori), entrectinib (Rozlytrek), repotrectinib (Augtyro), and taletrectinib (Ibtrozi) were approved earlier.<\/jats:p>","DOI":"10.58347\/tml.2026.1766f","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T15:44:06Z","timestamp":1792079046000},"page":"e177-e178","source":"Crossref","is-referenced-by-count":0,"title":["Zidesamtinib (Jideytro) \u2013 Another Kinase Inhibitor for NSCLC"],"prefix":"10.58347","volume":"68","member":"37151","published-online":{"date-parts":[[2026,10,26]]},"container-title":["The Medical Letter on Drugs and Therapeutics"],"original-title":[],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T15:44:06Z","timestamp":1792079046000},"score":1,"resource":{"primary":{"URL":"https:\/\/secure.medicalletter.org\/TML-article-1766f"}},"subtitle":[],"editor":[{"name":"Editors from The Medical Letter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,10,26]]},"references-count":0,"journal-issue":{"issue":"1766","published-online":{"date-parts":[[2026,10,26]]}},"URL":"https:\/\/doi.org\/10.58347\/tml.2026.1766f","relation":{},"ISSN":["1523-2859"],"issn-type":[{"value":"1523-2859","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,26]]}}}