{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T18:36:57Z","timestamp":1769020617617,"version":"3.49.0"},"reference-count":28,"publisher":"Korean Stroke Society","issue":"1","license":[{"start":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T00:00:00Z","timestamp":1672704000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008005","name":"Yonsei University College of Medicine","doi-asserted-by":"publisher","award":["6-2019-0191"],"award-info":[{"award-number":["6-2019-0191"]}],"id":[{"id":"10.13039\/501100008005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HC19C0028"],"award-info":[{"award-number":["HC19C0028"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["j-stroke.org"],"crossmark-restriction":true},"short-container-title":["J Stroke"],"published-print":{"date-parts":[[2023,1,31]]},"abstract":"<jats:p>Background and Purpose Left atrial or left atrial appendage (LA\/LAA) thrombi are frequently observed during cardioembolic evaluation in patients with ischemic stroke. This study aimed to investigate stroke outcomes in patients with LA\/LAA thrombus.Methods This retrospective study included patients admitted to a single tertiary center in Korea between January 2012 and December 2020. Patients with nonvalvular atrial fibrillation who underwent transesophageal echocardiography or multi-detector coronary computed tomography were included in the study. Poor outcome was defined as modified Rankin Scale score &gt;3 at 90 days. The inverse probability of treatment weighting analysis was performed.Results Of the 631 patients included in this study, 68 (10.7%) had LA\/LAA thrombi. Patients were likely to have a poor outcome when an LA\/LAA thrombus was detected (42.6% vs. 17.4%, P&lt;0.001). Inverse probability of treatment weighting analysis yielded a higher probability of poor outcomes in patients with LA\/LAA thrombus than in those without LA\/LAA thrombus (P&lt;0.001). Patients with LA\/LAA thrombus were more likely to have relevant arterial occlusion on angiography (36.3% vs. 22.4%, P=0.047) and a longer hospital stay (8 vs. 7 days, P&lt;0.001) than those without LA\/LAA thrombus. However, there was no difference in early neurological deterioration during hospitalization or major adverse cardiovascular events within 3 months between the two groups.Conclusions Patients with ischemic stroke who had an LA\/LAA thrombus were at risk of a worse functional outcome after 3 months, which was associated with relevant arterial occlusion and prolonged hospital stay.<\/jats:p>","DOI":"10.5853\/jos.2022.02068","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T00:18:41Z","timestamp":1672705121000},"page":"111-118","update-policy":"https:\/\/doi.org\/10.5853\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Impact of Left Atrial or Left Atrial Appendage Thrombus on Stroke Outcome: A Matched Control Analysis"],"prefix":"10.5853","volume":"25","author":[{"given":"JoonNyung","family":"Heo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyungwoo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Il Hyung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyo Suk","family":"Nam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6275-0024","authenticated-orcid":true,"given":"Young 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of transesophageal echocardiography and cardiac computed tomography for evaluation of left atrial thrombus and associated pathology: a review and critical analysis","author":"Pathan","year":"2018"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(09)60040-4"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.07.048"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/s0167-5273(96)02862-8"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2008.01336.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw007"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.84.1.223"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.5603\/kp.2016.0172"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1159\/000354315"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-012-9707-0"}],"container-title":["Journal of 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