{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:03:48Z","timestamp":1791849828138,"version":"4.3.4"},"reference-count":175,"publisher":"Korean Stroke Society","issue":"1","license":[{"start":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T00:00:00Z","timestamp":1672704000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["j-stroke.org"],"crossmark-restriction":true},"short-container-title":["J Stroke"],"published-print":{"date-parts":[[2023,1,31]]},"abstract":"<jats:p>In recent years, it has been convincingly demonstrated that acute brain injury may cause severe cardiac complications\u2014such as neurogenic stress cardiomyopathy (NSC), a specific form of takotsubo cardiomyopathy. The pathophysiology of these brain-heart interactions is complex and involves sympathetic hyperactivity, activation of the hypothalamic-pituitary-adrenal axis, as well as immune and inflammatory pathways. There have been great strides in our understanding of the axis from the brain to the heart in patients with isolated acute brain injury and more specifically in patients with stroke. On the other hand, in patients with NSC, research has mainly focused on hemodynamic dysfunction due to arrhythmias, regional wall motion abnormality, or left ventricular hypokinesia that leads to impaired cerebral perfusion pressure. Comparatively little is known about the underlying secondary and delayed cerebral complications. The aim of the present review is to describe the stroke-heart-brain axis and highlight the main pathophysiological mechanisms leading to secondary and delayed cerebral injury in patients with concurrent hemorrhagic or ischemic stroke and NSC as well as to identify further areas of research that could potentially improve outcomes in this specific patient population.<\/jats:p>","DOI":"10.5853\/jos.2022.02173","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T00:22:07Z","timestamp":1672705327000},"page":"39-54","update-policy":"https:\/\/doi.org\/10.5853\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["The Heart Is at Risk: Understanding Stroke-Heart-Brain Interactions with Focus on Neurogenic Stress Cardiomyopathy\u2014A Review"],"prefix":"10.5853","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5298-7925","authenticated-orcid":true,"given":"Mairi","family":"Ziaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aristomenis","family":"Exadaktylos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3882","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.accpm.2020.06.016"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4103\/aca.aca_176_17"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161\/circresaha.117.311170"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/5842182"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1385\/ncc:5:3:243"},{"key":"ref6","first-page":"137","volume-title":"Extracranial complications after traumatic brain injury: targeting the brain and the body","author":"Robba","year":"2020"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/s1566-0702(00)00220-4"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2016.10.010"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2015.12.014"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.01.022"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00022.2020"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2016.03.010"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-015-0332-6"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03778-0"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.09.468"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-019-0999-7"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.01.031"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2018.02.006"},{"key":"ref19","first-page":"2768","volume-title":"Post-stroke cardiovascular complications and neurogenic cardiac injury: JACC state-of-the-art review","author":"Sposato","year":"2020"},{"key":"ref20","first-page":"929","volume-title":"Clinical features and outcomes of takotsubo (stress) cardiomyopathy","author":"Templin","year":"2015"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/s1474-4422(18)30336-3"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.116.027121"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2019.06.004"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1253\/circj.cj-13-1276"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000016327.74392.02"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.106.471813"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.112.664318"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1159\/000341340"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1038\/ncpcardio1066"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy076"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.92.8.2183"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.112.111591"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.116.014304"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21459"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-014-4096-5"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jash.2010.05.001"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2555"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.75.suppl_2.s26"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1007\/s11011-021-00796-3"},{"key":"ref40","first-page":"940","volume-title":"Are neurogenic stress cardiomyopathy and takotsubo different syndromes with common pathways?: etiopathological insights on dysfunctional hearts","author":"Tavazzi","year":"2017"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.25.6.1105"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.115.010001"},{"key":"ref43","first-page":"291","volume-title":"Autonomic control of adrenal function","author":"Edwards","year":"1993"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-02885-8"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa043046"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90008-6"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2007.9982"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-009-0071-0"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeu046"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.105.558239"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.49.75"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2015.01.013"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1385\/ncc:4:3:199"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000114874.96688.54"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2012.09.006"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000138452.81003.4c"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000202684.29640.60"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24906"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1007\/s11936-996-0014-x"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-015-1181-5"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1177\/0885066613511054"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-017-0412-9"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11010002"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-10349-w"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2019.04.005"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.109.556753"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2005.03.039"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.05.022"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1159\/000341858"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-005-0666-4"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000151364.19066.a1"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1016\/0196-9781(92)90149-w"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.14581\/jer.14003"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq456"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.5811\/westjem.2011.2.1785"},{"key":"ref76","first-page":"1028","volume-title":"Early systolic dysfunction following traumatic brain injury: a cohort study","author":"Krishnamoorthy","year":"2017"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-002-1355-x"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.872"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4150291"},{"key":"ref80","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-05592-7"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz068"},{"key":"ref82","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.12.022"},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2018.12.006"},{"key":"ref84","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(81)90620-6"},{"key":"ref85","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.57.11.1986"},{"key":"ref86","doi-asserted-by":"publisher","DOI":"10.1161\/hs0901.095406"},{"key":"ref87","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-022-00780-2"},{"key":"ref88","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-006835"},{"key":"ref89","doi-asserted-by":"publisher","DOI":"10.1177\/0271678x15617954"},{"key":"ref90","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2010.204776"},{"key":"ref91","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(84)90892-1"},{"key":"ref92","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.11.059"},{"key":"ref93","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.06.056"},{"key":"ref94","doi-asserted-by":"publisher","DOI":"10.1016\/s0197-4580(00)00111-1"},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/4899688"},{"key":"ref96","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/2617970"},{"key":"ref97","doi-asserted-by":"publisher","DOI":"10.1016\/j.anclin.2016.04.002"},{"key":"ref98","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2014.07.026"},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.137260"},{"key":"ref100","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2001.95.5.0756"},{"key":"ref101","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00270.2015"},{"key":"ref102","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2020161"},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf047"},{"key":"ref104","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.02.00214502"},{"key":"ref105","doi-asserted-by":"publisher","DOI":"10.1097\/01.ccm.0000057900.19201.55"},{"key":"ref106","doi-asserted-by":"publisher","DOI":"10.1210\/endocr\/bqaa242"},{"key":"ref107","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.106.653964"},{"key":"ref108","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/695925"},{"key":"ref109","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.56.6.527"},{"key":"ref110","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(96)00118-x"},{"key":"ref111","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2013.190"},{"key":"ref112","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2008.05.003"},{"key":"ref113","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2010.01.006"},{"key":"ref114","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.11.024"},{"key":"ref115","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2007.09.006"},{"key":"ref116","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-019-01655-0"},{"key":"ref117","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063829"},{"key":"ref118","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2004.08.029"},{"key":"ref119","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.07.127"},{"key":"ref120","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/861231"},{"key":"ref121","first-page":"137","volume-title":"Interleukin-1beta and caspase-1: players in the regulation of age-related cognitive dysfunction","author":"Gemma","year":"2007"},{"key":"ref122","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2005.08.009"},{"key":"ref123","doi-asserted-by":"publisher","DOI":"10.2174\/15701611113119990003"},{"key":"ref124","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.4679"},{"key":"ref125","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0069123"},{"key":"ref126","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.119.236885"},{"key":"ref127","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3880"},{"key":"ref128","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2011.10.004"},{"key":"ref129","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2021.107119"},{"key":"ref130","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcn017"},{"key":"ref131","first-page":"279","volume-title":"Intraventricular thrombus formation and embolism in takotsubo syndrome: insights from the international takotsubo registry","author":"Ding","year":"2020"},{"key":"ref132","doi-asserted-by":"publisher","DOI":"10.1016\/j.hfc.2016.06.011"},{"key":"ref133","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.06.089"},{"key":"ref134","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.09.008"},{"key":"ref135","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.105.567297"},{"key":"ref136","doi-asserted-by":"publisher","DOI":"10.1002\/clc.23460"},{"key":"ref137","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-011-0132-6"},{"key":"ref138","doi-asserted-by":"publisher","DOI":"10.1080\/0953710031000092785"},{"key":"ref139","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000070542.18001.87"},{"key":"ref140","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.07.002"},{"key":"ref141","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000044389.51236.91"},{"key":"ref142","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-017-0661-8"},{"key":"ref143","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2022.01.005"},{"key":"ref144","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw293"},{"key":"ref145","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.07.053"},{"key":"ref146","doi-asserted-by":"publisher","DOI":"10.1161\/circep.116.004052"},{"key":"ref147","doi-asserted-by":"publisher","DOI":"10.1016\/b978-0-12-819814-8.00001-9"},{"key":"ref148","doi-asserted-by":"publisher","DOI":"10.11138\/fneur\/2016.31.3.157"},{"key":"ref149","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2021.106005"},{"key":"ref150","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000257964.65743.99"},{"key":"ref151","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.112.669788"},{"key":"ref152","first-page":"126","volume-title":"Fluid management of the neurological patient: a concise review","author":"van der Jagt","year":"2016"},{"key":"ref153","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.109.547463"},{"key":"ref154","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.113.001015"},{"key":"ref155","doi-asserted-by":"publisher","DOI":"10.1016\/s0167-5273(96)02879-3"},{"key":"ref156","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8020190"},{"key":"ref157","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcha.2022.100990"},{"key":"ref158","first-page":"A11626","volume-title":"Abstract 11626: faster recovery in takotsubo with prior beta-blocker use","author":"Abu Ghalyoun","year":"2019"},{"key":"ref159","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2015-308712"},{"key":"ref160","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.03.196"},{"key":"ref161","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000253186.23949.fd"},{"key":"ref162","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.98.13.1329"},{"key":"ref163","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6143.990"},{"key":"ref164","first-page":"952","volume-title":"Beta-blockers and traumatic brain injury: a systematic review and meta-analysis","author":"Alali","year":"2017"},{"key":"ref165","doi-asserted-by":"publisher","DOI":"10.1097\/ta.0000000000001747"},{"key":"ref166","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2017.04.022"},{"key":"ref167","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-141-11-200412070-00010"},{"key":"ref168","doi-asserted-by":"publisher","DOI":"10.23736\/s0375-9393.17.12043-2"},{"key":"ref169","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2015.12.005"},{"key":"ref170","doi-asserted-by":"publisher","DOI":"10.31083\/j.rcm2204132"},{"key":"ref171","doi-asserted-by":"publisher","DOI":"10.1016\/j.hfc.2016.06.008"},{"key":"ref172","doi-asserted-by":"publisher","DOI":"10.1016\/j.case.2017.09.008"},{"key":"ref173","doi-asserted-by":"publisher","DOI":"10.1080\/14779072.2019.1556098"},{"key":"ref174","doi-asserted-by":"publisher","DOI":"10.1038\/bjp.2008.52"},{"key":"ref175","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-013-2945-5"}],"container-title":["Journal of Stroke"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/j-stroke.org\/upload\/pdf\/jos-2022-02173.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/j-stroke.org\/journal\/view.php?doi=10.5853\/jos.2022.02173","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/j-stroke.org\/upload\/pdf\/jos-2022-02173.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T04:03:39Z","timestamp":1675656219000},"score":1,"resource":{"primary":{"URL":"http:\/\/j-stroke.org\/journal\/view.php?doi=10.5853\/jos.2022.02173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,31]]},"references-count":175,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"URL":"https:\/\/doi.org\/10.5853\/jos.2022.02173","relation":{},"ISSN":["2287-6391","2287-6405"],"issn-type":[{"value":"2287-6391","type":"print"},{"value":"2287-6405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,31]]},"assertion":[{"value":"2022-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-03","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-31","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}