{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T09:47:27Z","timestamp":1780048047993,"version":"3.53.1"},"reference-count":42,"publisher":"Korean Stroke Society","issue":"3","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01 AG062711"],"award-info":[{"award-number":["R01 AG062711"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006808","name":"University of North Carolina","doi-asserted-by":"publisher","award":["HHSN268201300001I\/ N01-HC-65233"],"award-info":[{"award-number":["HHSN268201300001I\/ N01-HC-65233"]}],"id":[{"id":"10.13039\/100006808","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006686","name":"University of Miami","doi-asserted-by":"publisher","award":["HHSN268201300004I\/ N01-HC-65234"],"award-info":[{"award-number":["HHSN268201300004I\/ N01-HC-65234"]}],"id":[{"id":"10.13039\/100006686","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007319","name":"Albert Einstein College of Medicine","doi-asserted-by":"crossref","award":["HHSN268201300002I\/N01-HC-65235"],"award-info":[{"award-number":["HHSN268201300002I\/N01-HC-65235"]}],"id":[{"id":"10.13039\/100007319","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100008522","name":"University of Illinois at Chicago","doi-asserted-by":"crossref","award":["HHSN268201300003I\/N01- HC-65236"],"award-info":[{"award-number":["HHSN268201300003I\/N01- HC-65236"]}],"id":[{"id":"10.13039\/100008522","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100007099","name":"San Diego State University","doi-asserted-by":"publisher","award":["HHSN268201300005I\/N01-HC-65237"],"award-info":[{"award-number":["HHSN268201300005I\/N01-HC-65237"]}],"id":[{"id":"10.13039\/100007099","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006545","name":"National Institute on Minority Health and Health Disparities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIH Institution-Office of Dietary Supplements"}],"content-domain":{"domain":["j-stroke.org"],"crossmark-restriction":true},"short-container-title":["J Stroke"],"published-print":{"date-parts":[[2023,9,30]]},"abstract":"<jats:p>Background and Purpose Social determinants of health (SDOH) are non-medical factors that may contribute to the development of diseases, with a higher representation in underserved populations. Our objective is to determine the association of unfavorable SDOH with self-reported stroke\/transient ischemic attack (TIA) and vascular risk factors (VRFs) among Hispanic\/Latino adults living in the US.Methods We used cross-sectional data from the Hispanic Community Health Study\/Study of Latinos. SDOH and VRFs were assessed using questionnaires and validated scales and measurements. We investigated the association between the SDOH (individually and as count: \u22641, 2, 3, 4, or \u22655 SDOH), VRFs and stroke\/TIA using regression analyses.Results For individuals with stroke\/TIA (n=388), the mean age (58.9 years) differed from those without stroke\/TIA (n=11,210; 46.8 years; &lt;i&gt;P&lt;\/i&gt;&lt;0.0001). In bivariate analysis, income &lt;$20,000, education less than high school, no health insurance, perceived discrimination, not currently employed, upper tertile for chronic stress, and lower tertiles for social support and language- and social-based acculturation were associated with stroke\/TIA and retained further. A higher number of SDOH was directly associated with all individual VRFs investigated, except for at-risk alcohol, and with number of VRFs (\u03b2=0.11, 95% confidence interval [CI]=0.09\u20130.14). In the fully adjusted model, income, discrimination, social support, chronic stress, and employment status were individually associated with stroke\/TIA; the odds of stroke\/TIA were 2.3 times higher in individuals with 3 SDOH (95% CI 1.6\u20133.2) and 2.7 times (95% CI 1.9\u20133.7) for those with \u22655 versus \u22641 SDOH.Conclusion Among Hispanic\/Latino adults, a higher number of SDOH is associated with increased odds for stroke\/TIA and VRFs. The association remained significant after adjustment for VRFs, suggesting involvement of non-vascular mechanisms.<\/jats:p>","DOI":"10.5853\/jos.2023.00626","type":"journal-article","created":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T07:27:36Z","timestamp":1691566056000},"page":"361-370","update-policy":"https:\/\/doi.org\/10.5853\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Association of Unfavorable Social Determinants of Health With Stroke\/Transient Ischemic Attack and Vascular Risk Factors in Hispanic\/Latino Adults: Results From Hispanic Community Health Study\/Study of Latinos"],"prefix":"10.5853","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3427-2605","authenticated-orcid":true,"given":"Gabriela","family":"Trifan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda 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