{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:08:43Z","timestamp":1770822523491,"version":"3.50.1"},"reference-count":26,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Context.<\/jats:italic>\n                    \u2014Automatic failure in gynecologic cytology proficiency testing occurs when a high-grade lesion or carcinoma (HSIL+, Category D) is misinterpreted as negative for intraepithelial lesion or malignancy (Category B).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Objectives.<\/jats:italic>\n                    \u2014To document the automatic failure rate in 2006 and 2007 from the College of American Pathologists proficiency testing program (PAP PT) and compare them to projected values from 2004.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Design.<\/jats:italic>\n                    \u2014Identify automatic failures from PAP PT in 2006 and 2007 and compare the rates of failure regarding participant and preparation type to validated slides in the College of American Pathologists Interlaboratory Comparison Program in 2004.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results.<\/jats:italic>\n                    \u2014There were 65\u200a264 participant responses for HSIL+ slides included in this analysis from 2006 and 2007. Overall, 1% (666 of 65\u200a264) of the HSIL+ responses were classified as negative, resulting in automatic failure for the participant. There were significantly fewer automatic failures in 2007 as compared with either 2006 or projected from 2004 data (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .001). Conventional preparations had a lower automatic failure rate than liquid-based preparations but only for 2006. Both pathologists and cytotechnologists interpreting liquid-based preparations faired better than projected from 2004 data.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions.<\/jats:italic>\n                    \u2014The automatic failure rate in PAP PT is lower than expected based on 2004 data from the College of American Pathologists Interlaboratory Comparison Program. Automatic failures are a relatively small component (1% or less) of proficiency testing failures. The rate of automatic failure decreased from 2006 to 2007 and may be due to loss of poor performers in the testing pool, the test-taking environment, or removal of less robust slides from the program.\n                  <\/jats:p>","DOI":"10.5858\/133.11.1757","type":"journal-article","created":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T08:22:19Z","timestamp":1613118139000},"page":"1757-1760","source":"Crossref","is-referenced-by-count":4,"title":["Automatic Failure in Gynecologic Cytology Proficiency Testing"],"prefix":"10.5858","volume":"133","author":[{"given":"Ann T.","family":"Moriarty","sequence":"first","affiliation":[{"name":"From the Department of Pathology, AmeriPath Indiana, Indianapolis Indiana (Dr Moriarty); the Department of Pathology and Area Laboratory Services, Walter Reed Army Medical Center, Washington, DC (Dr Crothers); the Department of Pathology, University of Utah, Salt Lake City (Dr Bentz); the Statistics Department (Ms Souers) and Cytology Surveys (Ms Fatheree), College of American Pathologists, Northfield, Illinois; and the Department of Pathology, Massachusetts General Hospital, Boston (Dr Wilbur)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara A.","family":"Crothers","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, AmeriPath Indiana, Indianapolis Indiana (Dr Moriarty); the Department of Pathology and Area Laboratory Services, Walter Reed Army Medical Center, Washington, DC (Dr Crothers); the Department of Pathology, University of Utah, Salt Lake City (Dr Bentz); the Statistics Department (Ms Souers) and Cytology Surveys (Ms Fatheree), College of American Pathologists, Northfield, Illinois; and the Department of Pathology, Massachusetts General Hospital, Boston (Dr Wilbur)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel S.","family":"Bentz","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, AmeriPath Indiana, Indianapolis Indiana (Dr Moriarty); the Department of Pathology and Area Laboratory Services, Walter Reed Army Medical Center, Washington, DC (Dr Crothers); the Department of Pathology, University of Utah, Salt Lake City (Dr Bentz); the Statistics Department (Ms Souers) and Cytology Surveys (Ms Fatheree), College of American Pathologists, Northfield, Illinois; and the Department of Pathology, Massachusetts General Hospital, Boston (Dr Wilbur)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhona J.","family":"Souers","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, AmeriPath Indiana, Indianapolis Indiana (Dr Moriarty); the Department of Pathology and Area Laboratory Services, Walter Reed Army Medical Center, Washington, DC (Dr Crothers); the Department of Pathology, University of Utah, Salt Lake City (Dr Bentz); the Statistics Department (Ms Souers) and Cytology Surveys (Ms Fatheree), College of American Pathologists, Northfield, Illinois; and the Department of Pathology, Massachusetts General Hospital, Boston (Dr Wilbur)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa A.","family":"Fatheree","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, AmeriPath Indiana, Indianapolis Indiana (Dr Moriarty); the Department of Pathology and Area Laboratory Services, Walter Reed Army Medical Center, Washington, DC (Dr Crothers); the Department of Pathology, University of Utah, Salt Lake City (Dr Bentz); the Statistics Department (Ms Souers) and Cytology Surveys (Ms Fatheree), College of American Pathologists, Northfield, Illinois; and the Department of Pathology, Massachusetts General Hospital, Boston (Dr Wilbur)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C.","family":"Wilbur","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, AmeriPath Indiana, Indianapolis Indiana (Dr Moriarty); the Department of Pathology and Area Laboratory Services, Walter Reed Army Medical Center, Washington, DC (Dr Crothers); the Department of Pathology, University of Utah, Salt Lake City (Dr Bentz); the Statistics Department (Ms Souers) and Cytology Surveys (Ms Fatheree), College of American Pathologists, Northfield, Illinois; and the Department of Pathology, Massachusetts General Hospital, Boston (Dr Wilbur)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3906","reference":[{"key":"i1543-2165-133-11-1757-b1","unstructured":"Clinical Laboratory Improvement Amendments of 1988 Final Rule.\n          \n          Fed Regist. 1992;57:7001\u20137186."},{"key":"i1543-2165-133-11-1757-b2","unstructured":"Medicare, Medicaid, and CLIA Programs: Statutory and Regulatory Requirements Related to Laboratory Participation in Proficiency Testing and Availability of Proficiency Testing Programs in Cytology.\n          \n          Baltimore, MD: Centers for Medicare & Medicaid Services; 2005."},{"key":"i1543-2165-133-11-1757-b3","series-title":"Arch Pathol Lab Med","first-page":"1114","article-title":"The potential for failure in gynecologic proficiency testing with current slide validation criteria: results from the College of American Pathologists Interlaboratory Comparison in Gynecologic Cytology Program.","volume":"130","author":"Young, N. A.","year":"2006","unstructured":"Young, N. A., A. T.Moriarty, M. K.Walsh, E.Wang, and D. C.Wilbur. The potential for failure in gynecologic proficiency testing with current slide validation criteria: results from the College of American Pathologists Interlaboratory Comparison in Gynecologic Cytology Program.Arch Pathol Lab Med2006. 130:1114\u20131118."},{"key":"i1543-2165-133-11-1757-b4","unstructured":"2006 PAP Gynecologic Cytology PT Program (PAP PT) Year-End Summary Report.\n          \n          Northfield, IL: College of American Pathologists; 2006."},{"key":"i1543-2165-133-11-1757-b5","series-title":"Arch Pathol Lab Med","first-page":"1119","article-title":"Robustness of validation criteria in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology.","volume":"130","author":"Renshaw, A. A.","year":"2006","unstructured":"Renshaw, A. A., M. K.Walsh, B.Blond, A. T.Moriarty, D. R.Mody, and T. 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Cytologic features of high-grade squamous intraepithelial lesion in ThinPrep Papanicolaou test slides: comparison of cases that performed poorly with those that performed well in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology.Arch Pathol Lab Med2004. 128:746\u2013748."},{"key":"i1543-2165-133-11-1757-b12","series-title":"Arch Pathol Lab Med","first-page":"733","article-title":"Cytologic features of high-grade squamous intraepithelial lesion in conventional slides: what is the difference between cases that perform well and those that perform poorly?","volume":"129","author":"Renshaw, A. A.","year":"2005","unstructured":"Renshaw, A. A., M. U.Prey, L.Hodes, M.Weisson, J.Haja, and A. T.Moriarty. 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S.Bentz, L. A.Fatheree, R. J.Souers, and D. C.Wilbur. Changes in participant performance in the \u201ctest-taking\u201d environment: observations from the 2006 College of American Pathologists Gynecologic Cytology Proficiency Testing Program (PAP PT).Arch Pathol Lab Med2009. 133:279\u2013282."},{"key":"i1543-2165-133-11-1757-b9","series-title":"Arch Pathol Lab Med","first-page":"44","article-title":"Appeals in Gynecologic Cytology Proficiency Testing (PT): review of 2006 PT from the College of American Pathologists (CAP).","volume":"133","author":"Crothers, B. A.","year":"2009","unstructured":"Crothers, B. A., A. T.Moriarty, L.Fatheree, C. N.Booth, W.Tench, and D. C.Wilbur. 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Cytologic features of high-grade squamous intraepithelial lesion in ThinPrep Papanicolaou test slides: comparison of cases that performed poorly with those that performed well in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology.Arch Pathol Lab Med2004. 128:746\u2013748."},{"key":"i1543-2165-133-11-1757-b12","series-title":"Arch Pathol Lab Med","first-page":"733","article-title":"Cytologic features of high-grade squamous intraepithelial lesion in conventional slides: what is the difference between cases that perform well and those that perform poorly?","volume":"129","author":"Renshaw, A. A.","year":"2005","unstructured":"Renshaw, A. A., M. U.Prey, L.Hodes, M.Weisson, J.Haja, and A. T.Moriarty. 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