{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T05:45:31Z","timestamp":1770788731295,"version":"3.50.0"},"reference-count":16,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Context.<\/jats:italic>\n                    \u2014The increasing use of contrast-enhanced magnetic resonance imaging (MRI) of the breast as a valuable adjunct to mammography and ultrasound in the detection of breast lesions, in association with needle core biopsy taken from the suspicious areas, has major workload implications for histopathology laboratories wherever breast MRI is practiced.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Objective.<\/jats:italic>\n                    \u2014To establish the number of histologic levels necessary for the evaluation of breast MRI-guided needle core biopsy specimens taken from suspicious areas on breast MRI examination.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Design.<\/jats:italic>\n                    \u2014Retrospective histologic review of a series of breast MRI-guided core needle biopsies, initially examined routinely at 4 levels, in the Pathology Department at Mount Sinai School of Medicine in New York, New York.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results.<\/jats:italic>\n                    \u2014Accurate diagnostic classification was possible after examination of the first level in 95.4% of cases. For a small group of patients (4.4%), 4 levels were considered to provide additional useful information, although this information did not alter the diagnosis. In only a single case (0.2%) was it likely that routine examination of 4 levels could have led to an incidental finding of a very small intraductal papilloma (0.15 cm) present only at the second histologic level. However, this incidental finding would have not changed the patient outcome.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions.<\/jats:italic>\n                    \u2014Needle core biopsies for MRI-detected abnormalities should be routinely examined at only 1 level. Further levels may be needed in occasional cases to identify more conclusively an associated pathologic abnormality and may be of particular value when assessing atypical intraductal proliferative epithelial lesions.\n                  <\/jats:p>","DOI":"10.5858\/133.12.1961","type":"journal-article","created":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T09:11:28Z","timestamp":1613121088000},"page":"1961-1964","source":"Crossref","is-referenced-by-count":7,"title":["Adequate Histologic Sampling of Breast Magnetic Resonance Imaging\u2013Guided Core Needle Biopsy"],"prefix":"10.5858","volume":"133","author":[{"given":"Virgilius","family":"Cornea","sequence":"first","affiliation":[{"name":"From the Department of Pathology, Mount Sinai School of Medicine, New York, New York (Drs Cornea and Nagi); and the Department of Pathology, Oncological Science, Mount Sinai Medical Center, New York, New York (Drs Jaffer and Bleiweiss). Dr Cornea is now with the Department of Pathology, University of Cincinnati, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shabnam","family":"Jaffer","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, Mount Sinai School of Medicine, New York, New York (Drs Cornea and Nagi); and the Department of Pathology, Oncological Science, Mount Sinai Medical Center, New York, New York (Drs Jaffer and Bleiweiss). Dr Cornea is now with the Department of Pathology, University of Cincinnati, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ira J.","family":"Bleiweiss","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, Mount Sinai School of Medicine, New York, New York (Drs Cornea and Nagi); and the Department of Pathology, Oncological Science, Mount Sinai Medical Center, New York, New York (Drs Jaffer and Bleiweiss). Dr Cornea is now with the Department of Pathology, University of Cincinnati, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandandeep","family":"Nagi","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, Mount Sinai School of Medicine, New York, New York (Drs Cornea and Nagi); and the Department of Pathology, Oncological Science, Mount Sinai Medical Center, New York, New York (Drs Jaffer and Bleiweiss). Dr Cornea is now with the Department of Pathology, University of Cincinnati, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3906","reference":[{"issue":"3","key":"i1543-2165-133-12-1961-b1","series-title":"Magn Reson Imaging Clin N Am","first-page":"411","article-title":"MRI-guided percutaneous biopsy of breast lesions: materials, techniques, success rates, and management in patients with suspected radiologic-pathologic mismatch.","volume":"14","author":"Floery, D.","year":"2006","unstructured":"Floery, D. and T. H.Helbich. MRI-guided percutaneous biopsy of breast lesions: materials, techniques, success rates, and management in patients with suspected radiologic-pathologic mismatch.Magn Reson Imaging Clin N Am2006. 143:411\u2013425."},{"issue":"8","key":"i1543-2165-133-12-1961-b2","series-title":"Arch Pathol Lab Med","first-page":"1055","article-title":"Adequate histologic sampling of breast core needle biopsies.","volume":"125","author":"Renshaw, A. A.","year":"2001","unstructured":"Renshaw, A. A.\n          \n          Adequate histologic sampling of breast core needle biopsies.\n          Arch Pathol Lab Med\n          2001. 1258:1055\u20131057."},{"key":"i1543-2165-133-12-1961-b3","series-title":"J Clin Pathol","first-page":"681","article-title":"Examination of breast needle core biopsy specimens performed for screen-detected microcalcification.","volume":"60","author":"Kumaraswamy, V.","year":"2007","unstructured":"Kumaraswamy, V. and P. J.Carder. Examination of breast needle core biopsy specimens performed for screen-detected microcalcification.J Clin Pathol2007. 60:681\u2013684."},{"key":"i1543-2165-133-12-1961-b4","series-title":"Am J Clin Pathol","first-page":"26","article-title":"Adequate tissue sampling of prostate core needle biopsies.","volume":"107","author":"Renshaw, A. A.","year":"1997","unstructured":"Renshaw, A. A.\n          \n          Adequate tissue sampling of prostate core needle biopsies.\n          Am J Clin Pathol\n          1997. 107:26\u201329."},{"key":"i1543-2165-133-12-1961-b5","series-title":"Mod Pathol","first-page":"86A","article-title":"Diagnostic effect of complete histologic sampling of prostate needle biopsies [abstract].","volume":"10","author":"Reyes, A. O.","year":"1997","unstructured":"Reyes, A. O. and P. A.Humphrey. Diagnostic effect of complete histologic sampling of prostate needle biopsies [abstract].Mod Pathol1997. 10:86A."},{"key":"i1543-2165-133-12-1961-b6","series-title":"Am J Surg Pathol","first-page":"257","article-title":"How often are diagnostic features missed with less extensive histologic sampling of prostate needle biopsy specimens?","volume":"23","author":"Brat, D. J.","year":"1999","unstructured":"Brat, D. J., M. L.Wills, K. L.Lecksell, and J. I.Epstein. How often are diagnostic features missed with less extensive histologic sampling of prostate needle biopsy specimens?Am J Surg Pathol1999. 23:257\u2013262."},{"key":"i1543-2165-133-12-1961-b7","series-title":"Arch Pathol Lab Med","first-page":"833","article-title":"Needle biopsies of the prostate: what constitutes adequate histologic sampling?","volume":"122","author":"Lane, R. B.","year":"1998","unstructured":"Lane, R. B., C. G.Lane, K. A.Mangold, M. H.Johnson, and W. C.Allsbrook. Needle biopsies of the prostate: what constitutes adequate histologic sampling?Arch Pathol Lab Med1998. 122:833\u2013835."},{"key":"i1543-2165-133-12-1961-b8","series-title":"Int Semin Surg Oncol","first-page":"1","article-title":"Breast papillomas: current management with a focus on a new diagnostic and therapeutic modality.","volume":"3","author":"Al Sarakbi, W.","year":"2006","unstructured":"Al Sarakbi, W., D.Worku, P. F.Escobar, and K.Mokbel. Breast papillomas: current management with a focus on a new diagnostic and therapeutic modality.Int Semin Surg Oncol2006. 3:1."},{"issue":"3","key":"i1543-2165-133-12-1961-b1","series-title":"Magn Reson Imaging Clin N Am","first-page":"411","article-title":"MRI-guided percutaneous biopsy of breast lesions: materials, techniques, success rates, and management in patients with suspected radiologic-pathologic mismatch.","volume":"14","author":"Floery, D.","year":"2006","unstructured":"Floery, D. and T. H.Helbich. MRI-guided percutaneous biopsy of breast lesions: materials, techniques, success rates, and management in patients with suspected radiologic-pathologic mismatch.Magn Reson Imaging Clin N Am2006. 143:411\u2013425."},{"issue":"8","key":"i1543-2165-133-12-1961-b2","series-title":"Arch Pathol Lab Med","first-page":"1055","article-title":"Adequate histologic sampling of breast core needle biopsies.","volume":"125","author":"Renshaw, A. A.","year":"2001","unstructured":"Renshaw, A. A.\n          \n          Adequate histologic sampling of breast core needle biopsies.\n          Arch Pathol Lab Med\n          2001. 1258:1055\u20131057."},{"key":"i1543-2165-133-12-1961-b3","series-title":"J Clin Pathol","first-page":"681","article-title":"Examination of breast needle core biopsy specimens performed for screen-detected microcalcification.","volume":"60","author":"Kumaraswamy, V.","year":"2007","unstructured":"Kumaraswamy, V. and P. J.Carder. Examination of breast needle core biopsy specimens performed for screen-detected microcalcification.J Clin Pathol2007. 60:681\u2013684."},{"key":"i1543-2165-133-12-1961-b4","series-title":"Am J Clin Pathol","first-page":"26","article-title":"Adequate tissue sampling of prostate core needle biopsies.","volume":"107","author":"Renshaw, A. A.","year":"1997","unstructured":"Renshaw, A. A.\n          \n          Adequate tissue sampling of prostate core needle biopsies.\n          Am J Clin Pathol\n          1997. 107:26\u201329."},{"key":"i1543-2165-133-12-1961-b5","series-title":"Mod Pathol","first-page":"86A","article-title":"Diagnostic effect of complete histologic sampling of prostate needle biopsies [abstract].","volume":"10","author":"Reyes, A. O.","year":"1997","unstructured":"Reyes, A. O. and P. A.Humphrey. Diagnostic effect of complete histologic sampling of prostate needle biopsies [abstract].Mod Pathol1997. 10:86A."},{"key":"i1543-2165-133-12-1961-b6","series-title":"Am J Surg Pathol","first-page":"257","article-title":"How often are diagnostic features missed with less extensive histologic sampling of prostate needle biopsy specimens?","volume":"23","author":"Brat, D. J.","year":"1999","unstructured":"Brat, D. J., M. L.Wills, K. L.Lecksell, and J. I.Epstein. How often are diagnostic features missed with less extensive histologic sampling of prostate needle biopsy specimens?Am J Surg Pathol1999. 23:257\u2013262."},{"key":"i1543-2165-133-12-1961-b7","series-title":"Arch Pathol Lab Med","first-page":"833","article-title":"Needle biopsies of the prostate: what constitutes adequate histologic sampling?","volume":"122","author":"Lane, R. B.","year":"1998","unstructured":"Lane, R. B., C. G.Lane, K. A.Mangold, M. H.Johnson, and W. C.Allsbrook. Needle biopsies of the prostate: what constitutes adequate histologic sampling?Arch Pathol Lab Med1998. 122:833\u2013835."},{"key":"i1543-2165-133-12-1961-b8","series-title":"Int Semin Surg Oncol","first-page":"1","article-title":"Breast papillomas: current management with a focus on a new diagnostic and therapeutic modality.","volume":"3","author":"Al Sarakbi, W.","year":"2006","unstructured":"Al Sarakbi, W., D.Worku, P. F.Escobar, and K.Mokbel. Breast papillomas: current management with a focus on a new diagnostic and therapeutic modality.Int Semin Surg Oncol2006. 3:1."}],"container-title":["Archives of Pathology &amp; Laboratory Medicine"],"original-title":[],"link":[{"URL":"https:\/\/aplm.kglmeridian.com\/view\/journals\/arpa\/133\/12\/article-p1961.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/aplm\/article-pdf\/133\/12\/1961\/2766841\/1543-2165-133_12_1961.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/aplm.kglmeridian.com\/downloadpdf\/journals\/arpa\/133\/12\/article-p1961.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/aplm.kglmeridian.com\/downloadpdf\/journals\/arpa\/133\/12\/article-p1961.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T01:05:22Z","timestamp":1770771922000},"score":1,"resource":{"primary":{"URL":"https:\/\/aplm.kglmeridian.com\/view\/journals\/arpa\/133\/12\/article-p1961.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":16,"journal-issue":{"issue":"12"},"URL":"https:\/\/doi.org\/10.5858\/133.12.1961","relation":{},"ISSN":["1543-2165","0003-9985"],"issn-type":[{"value":"1543-2165","type":"electronic"},{"value":"0003-9985","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}