{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T03:59:01Z","timestamp":1785556741625,"version":"3.56.0"},"reference-count":20,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We report a new case of aneurysmal bone cyst of the larynx occurring in a 22-year-old man. The lesion manifested with progressive breathing discomfort and appeared as a polypoid pedunculated mass attached to the subglottic mucosa. Microscopically, it featured numerous mononuclear and multinucleated giant cells surrounding cavernous spaces filled with blood. Foci of proliferating spindle cells and mature osteoid tissue could be recognized. There was no apparent relationship with the cricoid perichondrium. Clinical follow-up was negative for local recurrence. Based on this report and a review of the literature, we conclude that aneurysmal bone cyst of the larynx is phenotypically comparable to its bone homologue; however, its microscopic recognition may be difficult, especially on small biopsy fragments. Since it can be confused with several lesions, including telangiectatic osteosarcoma, awareness of this rare appearance of aneurysmal bone cyst is important to avoid unnecessary radical surgery.<\/jats:p>","DOI":"10.5858\/2001-125-0673-abcotl","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T00:15:35Z","timestamp":1611879335000},"page":"673-676","source":"Crossref","is-referenced-by-count":14,"title":["Aneurysmal Bone Cyst of the Larynx Presenting With Hypoglottic Obstruction"],"prefix":"10.5858","volume":"125","author":[{"given":"Duilio Della","family":"Libera","sequence":"first","affiliation":[{"name":"From the Division of Anatomic Pathology, City Hospital, Conegliano (TV), Italy (Drs Della Libera, Bittesini, and Falconieri); and the Department of Pathology, M. D. Anderson Cancer Center, Houston, Tex (Dr Redlich)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian","family":"Redlich","sequence":"additional","affiliation":[{"name":"From the Division of Anatomic Pathology, City Hospital, Conegliano (TV), Italy (Drs Della Libera, Bittesini, and Falconieri); and the Department of Pathology, M. D. Anderson Cancer Center, Houston, Tex (Dr Redlich)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Bittesini","sequence":"additional","affiliation":[{"name":"From the Division of Anatomic Pathology, City Hospital, Conegliano (TV), Italy (Drs Della Libera, Bittesini, and Falconieri); and the Department of Pathology, M. D. Anderson Cancer Center, Houston, Tex (Dr Redlich)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Falconieri","sequence":"additional","affiliation":[{"name":"Reprints: Giovanni Falconieri, MD, Division of Anatomic Pathology, City Hospital, I 31015 Conegliano TV, Italy (falcopath@yahoo.com)."},{"name":"From the Division of Anatomic Pathology, City Hospital, Conegliano (TV), Italy (Drs Della Libera, Bittesini, and Falconieri); and the Department of Pathology, M. D. Anderson Cancer Center, Houston, Tex (Dr Redlich)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3906","reference":[{"key":"i1543-2165-125-5-673-b1","series-title":"Surg Gynecol Obstet","first-page":"989","article-title":"Supporting tissue neoplasms of the larynx.","volume":"131","author":"Batsakis, J. G.","year":"1970","unstructured":"Batsakis, J. G. and J. E.Fox. Supporting tissue neoplasms of the larynx.Surg Gynecol Obstet1970. 131:989\u2013997."},{"key":"i1543-2165-125-5-673-b2","series-title":"Arch Pathol Lab Med","first-page":"834","article-title":"Giant cell tumor of the larynx: case report and review of the literature.","volume":"118","author":"Martin, P. C.","year":"1994","unstructured":"Martin, P. C., S. A.Hoda, H. T.Pigman, and D. R.Pulitzer. Giant cell tumor of the larynx: case report and review of the literature.Arch Pathol Lab Med1994. 118:834\u2013837."},{"key":"i1543-2165-125-5-673-b3","series-title":"Am J Otolaryngol","first-page":"370","article-title":"Aneurysmal bone cyst of the larynx.","volume":"7","author":"Schilling, H. E.","year":"1986","unstructured":"Schilling, H. E., G. D.Neal, M.Nathan, and T. B.Aufdemorte. Aneurysmal bone cyst of the larynx.Am J Otolaryngol1986. 7:370\u2013374."},{"key":"i1543-2165-125-5-673-b4","series-title":"Head Neck","first-page":"457","article-title":"Aneurysmal bone cyst of the cricoid cartilage: an unusual cause of subglottic stenosis.","volume":"13","author":"Sercarz, J. A.","year":"1991","unstructured":"Sercarz, J. A., M.Robert, D.Alessi, Y. S.Fu, and T. C.Calcaterra. Aneurysmal bone cyst of the cricoid cartilage: an unusual cause of subglottic stenosis.Head Neck1991. 13:457\u2013460."},{"key":"i1543-2165-125-5-673-b5","first-page":"103","article-title":"Immunoperoxidase techniques.","author":"Nadji, M.","year":"1990","unstructured":"Nadji, M. and A. R.Morales. Immunoperoxidase techniques.In: Silverberg SS, ed. Principles and Practice of Surgical Pathology. New York, NY: Churchill-Livingstone. 1990. 103\u2013118."},{"key":"i1543-2165-125-5-673-b6","article-title":"Tumors of the Bones and Joints.","author":"Fechner, R. E.","unstructured":"Fechner, R. E. and S. E.Mills. Tumors of the Bones and Joints.Washington, DC: Armed Forces Institute of Pathology; 1993. Atlas of Tumor Pathology; 3rd series, fascicle 8."},{"key":"i1543-2165-125-5-673-b7","series-title":"Am J Surg Pathol","first-page":"632","article-title":"Primary aneurysmal cyst of soft tissues (extraosseous aneurysmal cyst).","volume":"18","author":"Rodriguez-Peralto, J. L.","year":"1994","unstructured":"Rodriguez-Peralto, J. L., F.Lopez-Barea, S.S\u00e0nchez-Herrea, and M.Atienza. Primary aneurysmal cyst of soft tissues (extraosseous aneurysmal cyst).Am J Surg Pathol1994. 18:632\u2013636."},{"key":"i1543-2165-125-5-673-b8","series-title":"Virchows Arch","first-page":"125","article-title":"Primary aneurysmal cyst of soft tissue: report of a case with ultrastructural and MRI studies.","volume":"428","author":"Lopez-Barea, F.","year":"1996","unstructured":"Lopez-Barea, F., J. L.Rodriguez-Peralto, E.Burgos-Lizaldez, J.Alvarez-Linera, and S.S\u00e0nchez-Herrea. 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