{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T21:36:20Z","timestamp":1773956180130,"version":"3.50.1"},"reference-count":10,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>An otherwise healthy 85-year-old woman presented with purulent multifocal subcutaneous nodules on the dorsal side of the right forearm and hand. Histopathologic examination of the biopsied specimen showed a subcutaneous granuloma with central abscess and necrosis, consistent with phaeomycotic cyst. Faint brown septate hyphae and moniliform fungal elements were found in the granuloma. Culture of the discharge grew Phialophora verrucosa. This fungus has rarely been reported as a pathogen of subcutaneous phaeohyphomycosis. Subcutaneous phaeohyphomycosis usually presents as a single lesion. In this case of multifocal lesions, initial imperfect excision seems to have caused satellite lesions. To our knowledge, this is the first report of multifocal subcutaneous phaeohyphomycosis caused by P verrucosa. The disease responded to oral itraconazole administration.<\/jats:p>","DOI":"10.5858\/2003-127-91-mspcbp","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T04:56:23Z","timestamp":1611896183000},"page":"91-93","source":"Crossref","is-referenced-by-count":29,"title":["Multifocal Subcutaneous Phaeohyphomycosis Caused by\n                    <i>Phialophora verrucosa<\/i>"],"prefix":"10.5858","volume":"127","author":[{"given":"Masatomo","family":"Kimura","sequence":"first","affiliation":[{"name":"From the Second Department of Pathology, Kinki University School of Medicine, Osaka-Sayama, Japan (Drs Kimura, Furuta, Satou, and Hashimoto); the Department of Dermatology, Minami Wakayama National Hospital, Tanabe, Japan (Dr Goto); and Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba, Japan (Dr Nishimura)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"Goto","sequence":"additional","affiliation":[{"name":"From the Second Department of Pathology, Kinki University School of Medicine, Osaka-Sayama, Japan (Drs Kimura, Furuta, Satou, and Hashimoto); the Department of Dermatology, Minami Wakayama National Hospital, Tanabe, Japan (Dr Goto); and Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba, Japan (Dr Nishimura)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Furuta","sequence":"additional","affiliation":[{"name":"From the Second Department of Pathology, Kinki University School of Medicine, Osaka-Sayama, Japan (Drs Kimura, Furuta, Satou, and Hashimoto); the Department of Dermatology, Minami Wakayama National Hospital, Tanabe, Japan (Dr Goto); and Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba, Japan (Dr Nishimura)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Satou","sequence":"additional","affiliation":[{"name":"From the Second Department of Pathology, Kinki University School of Medicine, Osaka-Sayama, Japan (Drs Kimura, Furuta, Satou, and Hashimoto); the Department of Dermatology, Minami Wakayama National Hospital, Tanabe, Japan (Dr Goto); and Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba, Japan (Dr Nishimura)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeo","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"From the Second Department of Pathology, Kinki University School of Medicine, Osaka-Sayama, Japan (Drs Kimura, Furuta, Satou, and Hashimoto); the Department of Dermatology, Minami Wakayama National Hospital, Tanabe, Japan (Dr Goto); and Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba, Japan (Dr Nishimura)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuko","family":"Nishimura","sequence":"additional","affiliation":[{"name":"From the Second Department of Pathology, Kinki University School of Medicine, Osaka-Sayama, Japan (Drs Kimura, Furuta, Satou, and Hashimoto); the Department of Dermatology, Minami Wakayama National Hospital, Tanabe, Japan (Dr Goto); and Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba, Japan (Dr Nishimura)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3906","reference":[{"key":"2021020502590021000_i1543-2165-127-1-91-b1","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/S0891-5520(20)30236-1","article-title":"Infections caused by dematiaceous fungi: chromoblastomycosis and phaeohyphomycosis.","volume":"2","author":"Fader","year":"1988","journal-title":"Infect Dis Clin North Am"},{"key":"2021020502590021000_i1543-2165-127-1-91-b2","doi-asserted-by":"crossref","first-page":"901","DOI":"10.4269\/ajtmh.1980.29.901","article-title":"Phaeomycotic cyst: a clinicopathologic study of twenty-five patients.","volume":"29","author":"Ziefer","year":"1980","journal-title":"Am J Trop Med Hyg"},{"key":"2021020502590021000_i1543-2165-127-1-91-b3","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/BF00576368","article-title":"Subcutaneous cystic granuloma caused by Phialophora verrucosa.","volume":"64","author":"Iwatsu","year":"1978","journal-title":"Mycopathologia"},{"key":"2021020502590021000_i1543-2165-127-1-91-b4","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3314\/jjmm1960.25.379","article-title":"A case of phaeomycotic cyst caused by Phialophora verrucosa [in Japanese, English abstract].","volume":"25","author":"Kameda","year":"1984","journal-title":"Jpn J Med Mycol"},{"key":"2021020502590021000_i1543-2165-127-1-91-b5","first-page":"425","article-title":"Phialophora verrucosa\u2013induced subcutaneous phaeohyphomycosis.","volume":"30","author":"Schnadig","year":"1986","journal-title":"Acta Cytol"},{"key":"2021020502590021000_i1543-2165-127-1-91-b6","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/BF00482809","article-title":"Isolation of Phialophora verrucosa and Fonsecaea pedrosoi from nature in Japan.","volume":"75","author":"Iwatsu","year":"1981","journal-title":"Mycopathologia"},{"key":"2021020502590021000_i1543-2165-127-1-91-b7","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1080\/00362178485380771","article-title":"Subcutaneous phaeohyphomycosis caused by Exophiala spinifera.","volume":"22","author":"Padhye","year":"1984","journal-title":"J Med Vet Mycol"},{"key":"2021020502590021000_i1543-2165-127-1-91-b8","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/00000637-199507000-00022","article-title":"Nosocomial phaeomycotic cyst of the hand.","volume":"35","author":"Feldman","year":"1995","journal-title":"Ann Plast Surg"},{"key":"2021020502590021000_i1543-2165-127-1-91-b9","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1023\/A:1006815429916","article-title":"Two cases of cutaneous phaeohyphomycosis by Alternaria alternata and Alternaria tenuissima.","volume":"137","author":"Romano","year":"1997","journal-title":"Mycopathologia"},{"key":"2021020502590021000_i1543-2165-127-1-91-b10","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1592\/phco.19.11.995.31578","article-title":"Phaeohyphomycosis from Exophiala jeanselmei with concomitant Nocardia asteroides infection in a renal transplant recipient: case report and review of the literature.","volume":"19","author":"Sartoris","year":"1999","journal-title":"Pharmacotherapy"}],"container-title":["Archives of Pathology &amp; 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