{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T12:48:56Z","timestamp":1770814136676,"version":"3.50.1"},"reference-count":30,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We report a solitary fibrous tumor in the nasal cavity of a 48-year-old woman who presented with a history of bilateral nasal obstruction and long-standing cocaine inhalation. Physical examination revealed a large mass involving the right nasal cavity and extending into the posterior aspect of the left nasal cavity. The computed tomography scan showed opacification of airways. During surgery, the mass was found to involve the entire nasal cavity, with extension to the right maxillary sinus, posterior nasal airways, and left nasal cavity. The mass was completely excised. Pathologic examination revealed a polypoid mass 3.7 \u00d7 3.0 \u00d7 1.2 cm. This tumor was composed of spindle cells that were cytologically bland in a background of ropey and nodular collagen, giving a \u201cpatternless\u201d pattern. Immunohistochemically, the neoplastic cells stained for CD34 and vimentin but not for S100 protein, keratin, desmin, HMB-45, and c-Kit. This immunohistochemical pattern confirmed the diagnosis of solitary fibrous tumor. Although solitary fibrous tumors are usually found in the pleura, they can occur in various other locations, such as the orbit, nasal cavity, paranasal sinuses, mediastinum, breast, vagina, meninges, and soft tissues. This case is of interest because the tumor occurred in a patient with prolonged cocaine inhalation. Such an association has not been previously described. The exact causal relationship between cocaine inhalation and the tumor is not known.<\/jats:p>","DOI":"10.5858\/2004-128-e1-sftonc","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T14:53:55Z","timestamp":1612968835000},"page":"e1-e4","source":"Crossref","is-referenced-by-count":14,"title":["Solitary Fibrous Tumor of Nasal Cavity in Patient With Long-Standing History of Cocaine Inhalation"],"prefix":"10.5858","volume":"128","author":[{"given":"Suman S.","family":"Chauhan","sequence":"first","affiliation":[{"name":"From the Washington Hospital Center (Drs Chauhan and Krishnan) and the Armed Forces Institute of Pathology (Drs Chauhan and Heffner), Washington, DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayshree","family":"Krishnan","sequence":"additional","affiliation":[{"name":"From the Washington Hospital Center (Drs Chauhan and Krishnan) and the Armed Forces Institute of Pathology (Drs Chauhan and Heffner), Washington, DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis K.","family":"Heffner","sequence":"additional","affiliation":[{"name":"From the Washington Hospital Center (Drs Chauhan and Krishnan) and the Armed Forces Institute of Pathology (Drs Chauhan and Heffner), Washington, DC"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3906","reference":[{"key":"i1543-2165-128-1-e1-b1","series-title":"Cancer","first-page":"2678","article-title":"Solitary fibrous tumor of the pleura: eight new cases & review of 360 cases in the literature.","volume":"47","author":"Briselli, M.","year":"1981","unstructured":"Briselli, M., E. J.Mark, and G. R.Dickersin. Solitary fibrous tumor of the pleura: eight new cases & review of 360 cases in the literature.Cancer1981. 47:2678\u20132689."},{"key":"i1543-2165-128-1-e1-b2","series-title":"Virchows Arch A","first-page":"413","article-title":"Ultrastructural observations on the histogenesis of localised fibrous tumor of the pleura (benign mesothelioma).","volume":"403","author":"Burrig, K. F.","year":"1984","unstructured":"Burrig, K. F. and H.Kastendieck. Ultrastructural observations on the histogenesis of localised fibrous tumor of the pleura (benign mesothelioma).Virchows Arch A1984. 403:413\u2013424."},{"key":"i1543-2165-128-1-e1-b3","series-title":"Am J Surg Pathol","first-page":"640","article-title":"Localized benign and malignant fibrous tumors of the pleura.","volume":"13","author":"England, D. M.","year":"1989","unstructured":"England, D. M., L.Hochholzer, and M. J.McCarthy. Localized benign and malignant fibrous tumors of the pleura.Am J Surg Pathol1989. 13:640\u2013658."},{"key":"i1543-2165-128-1-e1-b4","series-title":"Otolaryngol Head Neck Surg","first-page":"826","article-title":"Solitary fibrous tumor of the nasal cavity.","volume":"121","author":"Kessler, A.","year":"1999","unstructured":"Kessler, A., J.Lapinsky, L.Berenholz, S.Sarfaty, and S.Segal. Solitary fibrous tumor of the nasal cavity.Otolaryngol Head Neck Surg1999. 121:826\u2013828."},{"key":"i1543-2165-128-1-e1-b5","series-title":"J Laryngol Otol","first-page":"468","article-title":"Solitary fibrous tumor arising in the nasal cavity: report of a case.","volume":"110","author":"Stringfellow, H. F.","year":"1996","unstructured":"Stringfellow, H. F., I. A.Khan, and M. C. J.Sissons. Solitary fibrous tumor arising in the nasal cavity: report of a case.J Laryngol Otol1996. 110:468\u2013470."},{"key":"i1543-2165-128-1-e1-b6","series-title":"Am J Surg Pathol","first-page":"126","article-title":"Solitary fibrous tumor of the nasal cavity and paranasal sinuses.","volume":"15","author":"Zukerberg, L. R.","year":"1991","unstructured":"Zukerberg, L. R., A. E.Rosenberg, G.Randolph, B. Z.Pilch, and M. L.Goodman. Solitary fibrous tumor of the nasal cavity and paranasal sinuses.Am J Surg Pathol1991. 15:126\u2013130."},{"key":"i1543-2165-128-1-e1-b7","series-title":"Histopathology","first-page":"67","article-title":"Solitary (localized) fibrous mesothelioma: evidence against mesothelial cell origin.","volume":"108","author":"Dervan, P. A.","year":"1986","unstructured":"Dervan, P. A., B.Tobin, and M.O'Connor. Solitary (localized) fibrous mesothelioma: evidence against mesothelial cell origin.Histopathology1986. 108:67\u201375."},{"key":"i1543-2165-128-1-e1-b8","series-title":"Am J Surg Pathol","first-page":"80","article-title":"Expression of CD34 by solitary fibrous tumors of the pleura, mediastinum, and lung.","volume":"18","author":"Van de Rijn, M.","year":"1994","unstructured":"Van de Rijn, M., C. M.Lombard, and R. V.Rouse. Expression of CD34 by solitary fibrous tumors of the pleura, mediastinum, and lung.Am J Surg Pathol1994. 18:80."},{"key":"i1543-2165-128-1-e1-b9","series-title":"Arch Otolaryngol","first-page":"172","article-title":"Hemangiopericytoma-like tumor of the nasal cavity.","volume":"107","author":"Aufdemorte, T. B.","year":"1981","unstructured":"Aufdemorte, T. B.\n          \n          Hemangiopericytoma-like tumor of the nasal cavity.\n          Arch Otolaryngol\n          1981. 107:172\u2013174."},{"key":"i1543-2165-128-1-e1-b10","series-title":"Am J Clin Pathol","first-page":"672","article-title":"Hemangiopericytoma-like intranasal tumors.","volume":"66","author":"Compagno, J.","year":"1976","unstructured":"Compagno, J. and V. J.Hyams. Hemangiopericytoma-like intranasal tumors.Am J Clin Pathol1976. 66:672\u2013683."},{"key":"i1543-2165-128-1-e1-b11","series-title":"Cancer","first-page":"15","article-title":"Pathology of juvenile nasopharyngeal angiofibroma\u2014a lesion of adolescent males.","volume":"7","author":"Sternberg, S. S.","year":"1954","unstructured":"Sternberg, S. 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K.\n          \n          Medical risks of cocaine use.\n          West Med J\n          1988. 148:440\u2013444."},{"key":"i1543-2165-128-1-e1-b14","series-title":"JAMA","first-page":"72","article-title":"Bilateral optic neuropathy and osteolytic sinusitis, complications of cocaine abuse.","volume":"259","author":"Newman, N. M.","year":"1988","unstructured":"Newman, N. M., D. A.DiLoreto, J. T.Ho, J. C.Klein, and N. S.Birnbowm. Bilateral optic neuropathy and osteolytic sinusitis, complications of cocaine abuse.JAMA1988. 259:72\u201374."},{"key":"i1543-2165-128-1-e1-b15","series-title":"Hum Pathol","first-page":"239","article-title":"Reactive vascular lesion of nasal septum simulating angiosarcoma in a cocaine abuser.","volume":"31","author":"Alameda, F.","year":"2000","unstructured":"Alameda, F., J.Fontane, J. M.Corominas, J.Lloreta, and S.Serrano. 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