{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T05:58:39Z","timestamp":1770789519616,"version":"3.50.0"},"reference-count":16,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In lung transplant patients, most infections produce radiographically diffuse or lobar infiltrates. Solitary nodules suggesting neoplasm may arise in lung transplant patients with lung infections. We describe a 45-year-old woman who underwent bilateral lung transplantation to treat bilateral bronchiectasis and lung fibrosis resulting from Hodgkin disease. Five months later, a solitary mass was identified on chest radiograph in the left upper lobe and left superior mediastinum. Low-power examination of wedge biopsies of the mass showed a florid proliferation of cells with clear to bubbly to eosinophilic cytoplasm and moderate nuclear atypia, proliferating fibroblasts, and necrosis, suggesting a clear cell carcinoma (possibly metastatic renal cell carcinoma). Intranuclear inclusions compatible with cytomegalovirus were identified on high-power examination and confirmed by immunohistochemistry. In lung transplant patients, a cytomegalovirus infection may mimic malignancy both radiographically and on initial histopathologic examination.<\/jats:p>","DOI":"10.5858\/2005-129-e1-cimaci","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T20:24:13Z","timestamp":1612988653000},"page":"e1-e3","source":"Crossref","is-referenced-by-count":4,"title":["Cytomegalovirus Infection Masquerading as Carcinoma in a Lung Transplant Patient"],"prefix":"10.5858","volume":"129","author":[{"given":"Timothy Craig","family":"Allen","sequence":"first","affiliation":[{"name":"From the Department of Pathology, University of Texas Health Center, Tyler (Dr Allen); the Departments of Medicine\u2013Pulmonary (Dr Bag) and Pathology (Dr Cagle), Baylor College of Medicine, Houston, Tex; and the Department of Pathology, University of Texas Health Science Center, Houston Medical School, Houston, Tex (Dr Zander). Dr Cagle is now with the Department of Pathology, The Methodist Hospital, Houston, Tex"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remzi","family":"Bag","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, University of Texas Health Center, Tyler (Dr Allen); the Departments of Medicine\u2013Pulmonary (Dr Bag) and Pathology (Dr Cagle), Baylor College of Medicine, Houston, Tex; and the Department of Pathology, University of Texas Health Science Center, Houston Medical School, Houston, Tex (Dr Zander). Dr Cagle is now with the Department of Pathology, The Methodist Hospital, Houston, Tex"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dani S.","family":"Zander","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, University of Texas Health Center, Tyler (Dr Allen); the Departments of Medicine\u2013Pulmonary (Dr Bag) and Pathology (Dr Cagle), Baylor College of Medicine, Houston, Tex; and the Department of Pathology, University of Texas Health Science Center, Houston Medical School, Houston, Tex (Dr Zander). Dr Cagle is now with the Department of Pathology, The Methodist Hospital, Houston, Tex"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip T.","family":"Cagle","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, University of Texas Health Center, Tyler (Dr Allen); the Departments of Medicine\u2013Pulmonary (Dr Bag) and Pathology (Dr Cagle), Baylor College of Medicine, Houston, Tex; and the Department of Pathology, University of Texas Health Science Center, Houston Medical School, Houston, Tex (Dr Zander). Dr Cagle is now with the Department of Pathology, The Methodist Hospital, Houston, Tex"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3906","reference":[{"key":"i1543-2165-129-1-e1-b1","article-title":"Clinical diagnosis of transplant-related problems.","author":"Nizami, I.","unstructured":"Nizami, I. and A. E.Frost. Clinical diagnosis of transplant-related problems.In: Cagle PT, ed. Diagnostic Pulmonary Pathology. New York, NY: Marcel Dekker; 2000:485\u2013499."},{"key":"i1543-2165-129-1-e1-b2","series-title":"J Heart Lung Transplant","first-page":"660","article-title":"Lung nodular lesions in heart transplant recipients.","volume":"19","author":"Munoz, P.","year":"2000","unstructured":"Munoz, P., J.Palomo, and P.Guembe. et al. Lung nodular lesions in heart transplant recipients.J Heart Lung Transplant2000. 19:660\u2013667."},{"key":"i1543-2165-129-1-e1-b3","series-title":"J Heart Lung Transplant","first-page":"1044","article-title":"Bronchogenic carcinoma complicating lung transplantation.","volume":"20","author":"Arcasoy, S. M.","year":"2001","unstructured":"Arcasoy, S. M., C.Hersh, and J. D.Christie. et al. Bronchogenic carcinoma complicating lung transplantation.J Heart Lung Transplant2001. 20:1044\u20131053."},{"key":"i1543-2165-129-1-e1-b4","series-title":"South Med J","first-page":"1121","article-title":"Cytomegalovirus pneumonia manifesting as a focal mass in acquired immunodeficiency syndrome.","volume":"89","author":"Fishman, J. E.","year":"1996","unstructured":"Fishman, J. E. and H. D.Batt. Cytomegalovirus pneumonia manifesting as a focal mass in acquired immunodeficiency syndrome.South Med J1996. 89:1121\u20131122."},{"key":"i1543-2165-129-1-e1-b5","series-title":"Chest","first-page":"1918","article-title":"Cytomegalovirus pneumonitis: an unusual cause of pulmonary nodules in a patient with AIDS.","volume":"103","author":"Northfelt, D. W.","year":"1993","unstructured":"Northfelt, D. W., R. A.Sollitto, and T. R.Miller. et al. Cytomegalovirus pneumonitis: an unusual cause of pulmonary nodules in a patient with AIDS.Chest1993. 103:1918\u20131920."},{"key":"i1543-2165-129-1-e1-b6","series-title":"J Thorac Imaging","first-page":"173","article-title":"Pulmonary nodules and masses after lung and heart-lung transplantation.","volume":"15","author":"Schulman, L. L.","year":"2000","unstructured":"Schulman, L. L., T.Htun, and C.Staniloae. et al. Pulmonary nodules and masses after lung and heart-lung transplantation.J Thorac Imaging2000. 15:173\u2013179."},{"key":"i1543-2165-129-1-e1-b7","series-title":"Chest","first-page":"165","article-title":"Pulmonary nodules in lung transplant recipients: etiology and outcome.","volume":"125","author":"Lee, P.","year":"2004","unstructured":"Lee, P., O. A.Minai, and A. C.Mehta. et al. Pulmonary nodules in lung transplant recipients: etiology and outcome.Chest2004. 125:165\u2013172."},{"key":"i1543-2165-129-1-e1-b8","series-title":"Mayo Clin Proc","first-page":"488","article-title":"Cytomegalovirus pneumonia mimicking lung cancer in an immunocompetent host.","volume":"78","author":"Karakelides, H.","year":"2003","unstructured":"Karakelides, H., M. C.Aubry, and J.Ryu. Cytomegalovirus pneumonia mimicking lung cancer in an immunocompetent host.Mayo Clin Proc2003. 78:488\u2013490."},{"key":"i1543-2165-129-1-e1-b1","article-title":"Clinical diagnosis of transplant-related problems.","author":"Nizami, I.","unstructured":"Nizami, I. and A. E.Frost. Clinical diagnosis of transplant-related problems.In: Cagle PT, ed. Diagnostic Pulmonary Pathology. New York, NY: Marcel Dekker; 2000:485\u2013499."},{"key":"i1543-2165-129-1-e1-b2","series-title":"J Heart Lung Transplant","first-page":"660","article-title":"Lung nodular lesions in heart transplant recipients.","volume":"19","author":"Munoz, P.","year":"2000","unstructured":"Munoz, P., J.Palomo, and P.Guembe. et al. Lung nodular lesions in heart transplant recipients.J Heart Lung Transplant2000. 19:660\u2013667."},{"key":"i1543-2165-129-1-e1-b3","series-title":"J Heart Lung Transplant","first-page":"1044","article-title":"Bronchogenic carcinoma complicating lung transplantation.","volume":"20","author":"Arcasoy, S. M.","year":"2001","unstructured":"Arcasoy, S. M., C.Hersh, and J. D.Christie. et al. Bronchogenic carcinoma complicating lung transplantation.J Heart Lung Transplant2001. 20:1044\u20131053."},{"key":"i1543-2165-129-1-e1-b4","series-title":"South Med J","first-page":"1121","article-title":"Cytomegalovirus pneumonia manifesting as a focal mass in acquired immunodeficiency syndrome.","volume":"89","author":"Fishman, J. E.","year":"1996","unstructured":"Fishman, J. E. and H. D.Batt. Cytomegalovirus pneumonia manifesting as a focal mass in acquired immunodeficiency syndrome.South Med J1996. 89:1121\u20131122."},{"key":"i1543-2165-129-1-e1-b5","series-title":"Chest","first-page":"1918","article-title":"Cytomegalovirus pneumonitis: an unusual cause of pulmonary nodules in a patient with AIDS.","volume":"103","author":"Northfelt, D. W.","year":"1993","unstructured":"Northfelt, D. W., R. A.Sollitto, and T. R.Miller. et al. Cytomegalovirus pneumonitis: an unusual cause of pulmonary nodules in a patient with AIDS.Chest1993. 103:1918\u20131920."},{"key":"i1543-2165-129-1-e1-b6","series-title":"J Thorac Imaging","first-page":"173","article-title":"Pulmonary nodules and masses after lung and heart-lung transplantation.","volume":"15","author":"Schulman, L. L.","year":"2000","unstructured":"Schulman, L. L., T.Htun, and C.Staniloae. et al. Pulmonary nodules and masses after lung and heart-lung transplantation.J Thorac Imaging2000. 15:173\u2013179."},{"key":"i1543-2165-129-1-e1-b7","series-title":"Chest","first-page":"165","article-title":"Pulmonary nodules in lung transplant recipients: etiology and outcome.","volume":"125","author":"Lee, P.","year":"2004","unstructured":"Lee, P., O. A.Minai, and A. C.Mehta. et al. 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