{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:09:58Z","timestamp":1770822598241,"version":"3.50.1"},"reference-count":22,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We report a case of basaloid squamous carcinoma of the hypopharynx with an extensive spindle cell component in an 82-year-old man. The tumor (4.0 \u00d7 2.5 \u00d7 2.2 cm) was a pedunculated polypoid mass that was attached to the left pyriform sinus. Histologically, most (70%) of the tumor was composed of malignant spindle cell proliferation, and the rest (30%) was basaloid squamous carcinoma. Some of the spindle cells were positive for cytokeratins. The preoperative histologic diagnosis was difficult because the endoscopic biopsy specimens showed only spindle cell proliferation. This is an unusual presentation of basaloid squamous carcinoma of the head and neck.<\/jats:p>","DOI":"10.5858\/2005-129-e94-bscoth","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T19:20:08Z","timestamp":1612984808000},"page":"e94-e96","source":"Crossref","is-referenced-by-count":8,"title":["Basaloid Squamous Carcinoma of the Hypopharynx With an Extensive Spindle Cell Component Exhibiting a Pedunculated Polypoid Mass"],"prefix":"10.5858","volume":"129","author":[{"given":"Tokuhiro","family":"Kimura","sequence":"first","affiliation":[{"name":"From the Departments of Pathology (Drs Kimura, Mukai, and Okada) and Otolaryngology-Head and Neck Surgery (Drs Shiotani, Moro, and Ikeda), Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makio","family":"Mukai","sequence":"additional","affiliation":[{"name":"From the Departments of Pathology (Drs Kimura, Mukai, and Okada) and Otolaryngology-Head and Neck Surgery (Drs Shiotani, Moro, and Ikeda), Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Shiotani","sequence":"additional","affiliation":[{"name":"From the Departments of Pathology (Drs Kimura, Mukai, and Okada) and Otolaryngology-Head and Neck Surgery (Drs Shiotani, Moro, and Ikeda), Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhisa","family":"Moro","sequence":"additional","affiliation":[{"name":"From the Departments of Pathology (Drs Kimura, Mukai, and Okada) and Otolaryngology-Head and Neck Surgery (Drs Shiotani, Moro, and Ikeda), Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asako","family":"Ikeda","sequence":"additional","affiliation":[{"name":"From the Departments of Pathology (Drs Kimura, Mukai, and Okada) and Otolaryngology-Head and Neck Surgery (Drs Shiotani, Moro, and Ikeda), Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasunori","family":"Okada","sequence":"additional","affiliation":[{"name":"From the Departments of Pathology (Drs Kimura, Mukai, and Okada) and Otolaryngology-Head and Neck Surgery (Drs Shiotani, Moro, and Ikeda), Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3906","reference":[{"key":"i1543-2165-129-4-e94-b1","series-title":"Hum Pathol","first-page":"1158","article-title":"Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases.","volume":"17","author":"Wain, S. L.","year":"1986","unstructured":"Wain, S. L., R.Kier, R. T.Vollmer, and E. H.Bossen. Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases.Hum Pathol1986. 17:1158\u20131166."},{"key":"i1543-2165-129-4-e94-b2","series-title":"Am J Clin Pathol","first-page":"159","article-title":"Carcinoma of the anal canal: a study of 79 cases.","volume":"83","author":"Dougherty, B. G.","year":"1985","unstructured":"Dougherty, B. G. and H. L.Evans. Carcinoma of the anal canal: a study of 79 cases.Am J Clin Pathol1985. 83:159\u2013164."},{"key":"i1543-2165-129-4-e94-b3","series-title":"Cancer","first-page":"1025","article-title":"Thymic carcinoma: a clinicopathologic study of 60 cases.","volume":"67","author":"Suster, S.","year":"1991","unstructured":"Suster, S. and J.Rosai. Thymic carcinoma: a clinicopathologic study of 60 cases.Cancer1991. 67:1025\u20131032."},{"key":"i1543-2165-129-4-e94-b4","series-title":"Am J Surg Pathol","first-page":"134","article-title":"\u201cAdenoid cystic\u201d carcinoma and adenoid basal carcinoma of the uterine cervix: a study of 28 cases.","volume":"12","author":"Ferry, J. A.","year":"1988","unstructured":"Ferry, J. A. and R. E.Scully. \u201cAdenoid cystic\u201d carcinoma and adenoid basal carcinoma of the uterine cervix: a study of 28 cases.Am J Surg Pathol1988. 12:134\u2013144."},{"key":"i1543-2165-129-4-e94-b5","series-title":"Histopathology","first-page":"35","article-title":"Basaloid-squamous carcinoma of the upper aerodigestive tract and so-called adenoid cystic carcinoma of the oesophagus: the same tumour type?","volume":"19","author":"Tsang, W. Y. W.","year":"1991","unstructured":"Tsang, W. Y. W., J. K. C.Chan, K. C.Lee, A. K. F.Leung, and Y. T.Fu. Basaloid-squamous carcinoma of the upper aerodigestive tract and so-called adenoid cystic carcinoma of the oesophagus: the same tumour type?Histopathology1991. 19:35\u201346."},{"key":"i1543-2165-129-4-e94-b6","article-title":".","author":"Wenig, B. M.","unstructured":"Wenig, B. M.\n          \n          .\n          Atlas of Head and Neck Pathology. Philadelphia, Pa: WB Saunders Co; 1993:227\u2013266."},{"key":"i1543-2165-129-4-e94-b7","series-title":"Arch Pathol Lab Med","first-page":"181","article-title":"Basaloid squamous cell carcinoma of the head and neck with a spindle cell component: an unusual histologic variant.","volume":"119","author":"Muller, S.","year":"1995","unstructured":"Muller, S. and L.Barnes. Basaloid squamous cell carcinoma of the head and neck with a spindle cell component: an unusual histologic variant.Arch Pathol Lab Med1995. 119:181\u2013182."},{"key":"i1543-2165-129-4-e94-b8","series-title":"Ann Otol Rhinol Laryngol","first-page":"1024","article-title":"Basaloid squamous cell carcinoma of the larynx and hypopharynx.","volume":"106","author":"Ferlito, A.","year":"1997","unstructured":"Ferlito, A., G.Altavilla, A.Rinaldo, and C.Doglioni. Basaloid squamous cell carcinoma of the larynx and hypopharynx.Ann Otol Rhinol Laryngol1997. 106:1024\u20131035."},{"key":"i1543-2165-129-4-e94-b9","article-title":"Tumors of the Upper Aerodigestive Tract and Ear.","author":"Mills, S. E.","unstructured":"Mills, S. E., M. J.Gaffey, and H. F.Frierson. Tumors of the Upper Aerodigestive Tract and Ear.Washington, DC: Armed Forces Institute of Pathology; 2000. Atlas of Tumor Pathology; 3rd series, fascicle 26."},{"key":"i1543-2165-129-4-e94-b10","series-title":"Arch Otolaryngol","first-page":"700","article-title":"Pseudosarcoma of the larynx: a comprehensive analysis.","volume":"106","author":"Lambert, P. R.","year":"1980","unstructured":"Lambert, P. R., P. H.Ward, and G.Berci. Pseudosarcoma of the larynx: a comprehensive analysis.Arch Otolaryngol1980. 106:700\u2013708."},{"key":"i1543-2165-129-4-e94-b11","series-title":"Hum Pathol","first-page":"664","article-title":"Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochemistry.","volume":"28","author":"Lewis, J. E.","year":"1997","unstructured":"Lewis, J. E., K. D.Olsen, and T. J.Sebo. Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochemistry.Hum Pathol1997. 28:664\u2013673."},{"key":"i1543-2165-129-4-e94-b1","series-title":"Hum Pathol","first-page":"1158","article-title":"Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases.","volume":"17","author":"Wain, S. L.","year":"1986","unstructured":"Wain, S. L., R.Kier, R. T.Vollmer, and E. H.Bossen. Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases.Hum Pathol1986. 17:1158\u20131166."},{"key":"i1543-2165-129-4-e94-b2","series-title":"Am J Clin Pathol","first-page":"159","article-title":"Carcinoma of the anal canal: a study of 79 cases.","volume":"83","author":"Dougherty, B. G.","year":"1985","unstructured":"Dougherty, B. G. and H. L.Evans. Carcinoma of the anal canal: a study of 79 cases.Am J Clin Pathol1985. 83:159\u2013164."},{"key":"i1543-2165-129-4-e94-b3","series-title":"Cancer","first-page":"1025","article-title":"Thymic carcinoma: a clinicopathologic study of 60 cases.","volume":"67","author":"Suster, S.","year":"1991","unstructured":"Suster, S. and J.Rosai. Thymic carcinoma: a clinicopathologic study of 60 cases.Cancer1991. 67:1025\u20131032."},{"key":"i1543-2165-129-4-e94-b4","series-title":"Am J Surg Pathol","first-page":"134","article-title":"\u201cAdenoid cystic\u201d carcinoma and adenoid basal carcinoma of the uterine cervix: a study of 28 cases.","volume":"12","author":"Ferry, J. A.","year":"1988","unstructured":"Ferry, J. A. and R. E.Scully. \u201cAdenoid cystic\u201d carcinoma and adenoid basal carcinoma of the uterine cervix: a study of 28 cases.Am J Surg Pathol1988. 12:134\u2013144."},{"key":"i1543-2165-129-4-e94-b5","series-title":"Histopathology","first-page":"35","article-title":"Basaloid-squamous carcinoma of the upper aerodigestive tract and so-called adenoid cystic carcinoma of the oesophagus: the same tumour type?","volume":"19","author":"Tsang, W. Y. W.","year":"1991","unstructured":"Tsang, W. Y. W., J. K. C.Chan, K. C.Lee, A. K. F.Leung, and Y. T.Fu. Basaloid-squamous carcinoma of the upper aerodigestive tract and so-called adenoid cystic carcinoma of the oesophagus: the same tumour type?Histopathology1991. 19:35\u201346."},{"key":"i1543-2165-129-4-e94-b6","article-title":".","author":"Wenig, B. M.","unstructured":"Wenig, B. M.\n          \n          .\n          Atlas of Head and Neck Pathology. Philadelphia, Pa: WB Saunders Co; 1993:227\u2013266."},{"key":"i1543-2165-129-4-e94-b7","series-title":"Arch Pathol Lab Med","first-page":"181","article-title":"Basaloid squamous cell carcinoma of the head and neck with a spindle cell component: an unusual histologic variant.","volume":"119","author":"Muller, S.","year":"1995","unstructured":"Muller, S. and L.Barnes. Basaloid squamous cell carcinoma of the head and neck with a spindle cell component: an unusual histologic variant.Arch Pathol Lab Med1995. 119:181\u2013182."},{"key":"i1543-2165-129-4-e94-b8","series-title":"Ann Otol Rhinol Laryngol","first-page":"1024","article-title":"Basaloid squamous cell carcinoma of the larynx and hypopharynx.","volume":"106","author":"Ferlito, A.","year":"1997","unstructured":"Ferlito, A., G.Altavilla, A.Rinaldo, and C.Doglioni. Basaloid squamous cell carcinoma of the larynx and hypopharynx.Ann Otol Rhinol Laryngol1997. 106:1024\u20131035."},{"key":"i1543-2165-129-4-e94-b9","article-title":"Tumors of the Upper Aerodigestive Tract and Ear.","author":"Mills, S. E.","unstructured":"Mills, S. E., M. J.Gaffey, and H. F.Frierson. Tumors of the Upper Aerodigestive Tract and Ear.Washington, DC: Armed Forces Institute of Pathology; 2000. Atlas of Tumor Pathology; 3rd series, fascicle 26."},{"key":"i1543-2165-129-4-e94-b10","series-title":"Arch Otolaryngol","first-page":"700","article-title":"Pseudosarcoma of the larynx: a comprehensive analysis.","volume":"106","author":"Lambert, P. R.","year":"1980","unstructured":"Lambert, P. R., P. H.Ward, and G.Berci. Pseudosarcoma of the larynx: a comprehensive analysis.Arch Otolaryngol1980. 106:700\u2013708."},{"key":"i1543-2165-129-4-e94-b11","series-title":"Hum Pathol","first-page":"664","article-title":"Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochemistry.","volume":"28","author":"Lewis, J. E.","year":"1997","unstructured":"Lewis, J. E., K. D.Olsen, and T. J.Sebo. Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochemistry.Hum Pathol1997. 28:664\u2013673."}],"container-title":["Archives of Pathology &amp; Laboratory Medicine"],"original-title":[],"link":[{"URL":"https:\/\/aplm.kglmeridian.com\/view\/journals\/arpa\/129\/4\/article-pe94.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/aplm\/article-pdf\/129\/4\/e94\/2756245\/1543-2165(2005)129_e94_bscoth_2_0_co_2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/aplm.kglmeridian.com\/downloadpdf\/journals\/arpa\/129\/4\/article-pe94.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/aplm.kglmeridian.com\/downloadpdf\/journals\/arpa\/129\/4\/article-pe94.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T01:13:38Z","timestamp":1770772418000},"score":1,"resource":{"primary":{"URL":"https:\/\/aplm.kglmeridian.com\/view\/journals\/arpa\/129\/4\/article-pe94.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4]]},"references-count":22,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.5858\/2005-129-e94-bscoth","relation":{},"ISSN":["1543-2165","0003-9985"],"issn-type":[{"value":"1543-2165","type":"electronic"},{"value":"0003-9985","type":"print"}],"subject":[],"published":{"date-parts":[[2005,4]]}}}