{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:32:46Z","timestamp":1770823966094,"version":"3.50.1"},"reference-count":9,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Black esophagus, or acute necrotizing esophagitis, is a blackening of the esophagus that is usually distal with a sharp demarcation at the gastroesophageal border. Black esophagus is known to the gastroenterology community; however, to our knowledge it is virtually unknown in the pathology literature with only a single instance described in 1967. It is thought to occur as a poorly elucidated ischemic phenomenon. We report a case of black esophagus in a 45-year-old woman with a history of cocaine and alcohol abuse who was found unresponsive after a vague 2-day illness. On autopsy examination, the esophagus was black with ischemic necrosis of the mucosa, submucosa, and muscularis propria including a diffuse acute inflammatory infiltrate and brown pigmentation limited to the mucosa. Positive periodic acid\u2013Schiff and negative iron stains suggest that the pigment is lipofuscin, likely secondary to ischemia.<\/jats:p>","DOI":"10.5858\/2010-0128-c.1","type":"journal-article","created":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T13:35:01Z","timestamp":1613136901000},"page":"797-798","source":"Crossref","is-referenced-by-count":30,"title":["A Case of Black Esophagus With Histopathologic Description and Characterization"],"prefix":"10.5858","volume":"135","author":[{"given":"Dana L.","family":"Altenburger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron S.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Garavaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3906","reference":[{"issue":"2","key":"2021021104304842200_i1543-2165-135-6-797-b01","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1442-2050.2006.00549.x","article-title":"Black esophagus: report of six cases and review of the literature, 1963\u20132003.","volume":"19","author":"Grudell","year":"2006","journal-title":"Dis Esophagus"},{"issue":"4","key":"2021021104304842200_i1543-2165-135-6-797-b02","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1136\/jcp.20.4.581","article-title":"Case of extensive necrosis of the oesophageal mucosa following hypothermia.","volume":"20","author":"Brennan","year":"1967","journal-title":"J Clin Pathol"},{"issue":"8","key":"2021021104304842200_i1543-2165-135-6-797-b03","first-page":"735","article-title":"Acute necrotizing esophagitis: a case report.","volume":"94","author":"Odelowo","year":"2002","journal-title":"J Natl Med Assoc"},{"issue":"1","key":"2021021104304842200_i1543-2165-135-6-797-b04","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ijsu.2009.09.014","article-title":"Acute esophageal necrosis: a case report and review of the literature.","volume":"8","author":"Day","year":"2010","journal-title":"Int J Surg"},{"issue":"2","key":"2021021104304842200_i1543-2165-135-6-797-b05","doi-asserted-by":"crossref","first-page":"133","DOI":"10.5009\/gnl.2008.2.2.133","article-title":"Black esophagus associated with alcohol abuse.","volume":"2","author":"Hong","year":"2008","journal-title":"Gut Liver"},{"issue":"35","key":"2021021104304842200_i1543-2165-135-6-797-b06","doi-asserted-by":"crossref","first-page":"5568","DOI":"10.3748\/wjg.v11.i35.5568","article-title":"Acute esophageal necrosis caused by alcohol abuse.","volume":"11","author":"Endo","year":"2005","journal-title":"World J Gastroenterol"},{"issue":"4","key":"2021021104304842200_i1543-2165-135-6-797-b07","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1155\/2007\/920716","article-title":"Acute esophageal necrosis and low-flow state.","volume":"21","author":"Brutally","year":"2007","journal-title":"Can J Gastroenterol"},{"issue":"4","key":"2021021104304842200_i1543-2165-135-6-797-b08","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0016-5107(99)70058-1","article-title":"Acute esophageal necrosis: report of two cases and a review of the literature.","volume":"49","author":"Lacy","year":"1999","journal-title":"Gastrointest Endosc"},{"issue":"16","key":"2021021104304842200_i1543-2165-135-6-797-b09","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.3748\/wjg.v10.i16.2457","article-title":"Acute esophageal necrosis and liver pathology, a rare combination.","volume":"10","author":"Khan","year":"2004","journal-title":"World J Gastroenterol"}],"container-title":["Archives of Pathology &amp; Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/meridian.allenpress.com\/aplm\/article-pdf\/135\/6\/797\/2771068\/2010-0128-c_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/meridian.allenpress.com\/aplm\/article-pdf\/135\/6\/797\/2771068\/2010-0128-c_1.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T19:33:18Z","timestamp":1764790398000},"score":1,"resource":{"primary":{"URL":"https:\/\/aplm.kglmeridian.com\/view\/journals\/arpa\/135\/6\/article-p797.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,1]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6,1]]}},"URL":"https:\/\/doi.org\/10.5858\/2010-0128-c.1","relation":{},"ISSN":["1543-2165","0003-9985"],"issn-type":[{"value":"1543-2165","type":"electronic"},{"value":"0003-9985","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6,1]]}}}