{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T16:57:54Z","timestamp":1773680274858,"version":"3.50.1"},"reference-count":42,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p>\n                    <jats:italic>Context<\/jats:italic>\n                    .\u2014Primary cutaneous diffuse large B-cell lymphoma, leg type, may show features that overlap with other lymphomas. However, timely recognition of this entity can have important clinical and therapeutic implications.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Objective<\/jats:italic>\n                    .\u2014To review the clinical, morphologic, and immunophenotypic characteristics of primary cutaneous diffuse large B-cell lymphoma, leg type, and juxtapose these features with other diagnostic considerations. In particular, other variants of primary cutaneous diffuse large B-cell lymphoma, as well as primary cutaneous follicle center lymphoma, will be reviewed. Additionally, systemic\/extracutaneous lymphomas will be discussed, including diffuse large B-cell lymphoma, not otherwise specified, Epstein-Barr virus\u2013positive diffuse large B-cell lymphoma of the elderly, and lymphomatoid granulomatosis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Data Sources<\/jats:italic>\n                    .\u2014Relevant literature will be reviewed and key differentiating findings will be highlighted.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions<\/jats:italic>\n                    .\u2014Although primary cutaneous diffuse large B-cell lymphoma, leg type, may show aspects that overlap with other lymphomas, it can be distinguished from other entities in the differential diagnosis.\n                  <\/jats:p>","DOI":"10.5858\/arpa.2012-0195-ra","type":"journal-article","created":{"date-parts":[[2012,7,31]],"date-time":"2012-07-31T11:01:31Z","timestamp":1343732491000},"page":"876-881","source":"Crossref","is-referenced-by-count":29,"title":["Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type: Diagnostic Considerations"],"prefix":"10.5858","volume":"136","author":[{"given":"Alexandra C.","family":"Hristov","sequence":"first","affiliation":[{"name":"From the Department of Pathology, Dermatopathology, University of Michigan, Ann Arbor."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3906","reference":[{"issue":"3, pt 1","key":"i1543-2165-136-8-876-b01","series-title":"J Am Acad Dermatol","first-page":"518","article-title":"Primary cutaneous large cell lymphomas of follicular center cell origin: a clinical follow-up study of nineteen patients","volume":"16","author":"Willemze\n              R,","year":"1987;","unstructured":"Willemze\n              R, \n            \n              Meijer\n              CJ, \n            \n              Sentis\n              HJ, \n            et al\n          . Primary cutaneous large cell lymphomas of follicular center cell origin: a clinical follow-up study of nineteen patients. J Am Acad Dermatol. 1987;16(3, pt 1):518\u2013526."},{"issue":"11","key":"i1543-2165-136-8-876-b02","series-title":"Arch Dermatol","first-page":"1304","article-title":"Primary cutaneous large B-cell lymphomas of the legs: a distinct type of cutaneous B-cell lymphoma with an intermediate prognosis; Dutch Cutaneous Lymphoma Working Group","volume":"132","author":"Vermeer\n              MH,","year":"1996;","unstructured":"Vermeer\n              MH, \n            \n              Geelen\n              FA, \n            \n              van Haselen\n              CW, \n            et al\n          . Primary cutaneous large B-cell lymphomas of the legs: a distinct type of cutaneous B-cell lymphoma with an intermediate prognosis; Dutch Cutaneous Lymphoma Working Group. Arch Dermatol. 1996;132(11):1304\u20131308."},{"issue":"1","key":"i1543-2165-136-8-876-b03","series-title":"Blood","first-page":"354","article-title":"EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer","volume":"90","author":"Willemze\n              R,","year":"1997;","unstructured":"Willemze\n              R, \n            \n              Kerl\n              H, \n            \n              Sterry\n              W, \n            et al\n          . EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer. Blood. 1997;90(1):354\u2013371."},{"issue":"16","key":"i1543-2165-136-8-876-b04","series-title":"J Clin Oncol","first-page":"3602","article-title":"Prognostic factors in primary cutaneous large B-cell lymphomas: a European multicenter study","volume":"19","author":"Grange\n              F,","year":"2001;","unstructured":"Grange\n              F, \n            \n              Bekkenk\n              MW, \n            \n              Wechsler\n              J, \n            et al\n          . Prognostic factors in primary cutaneous large B-cell lymphomas: a European multicenter study. J Clin Oncol. 2001;19(16):3602\u20133610."},{"issue":"10","key":"i1543-2165-136-8-876-b05","series-title":"Blood","first-page":"3768","article-title":"WHO-EORTC classification for cutaneous lymphomas","volume":"105","author":"Willemze\n              R,","year":"2005;","unstructured":"Willemze\n              R, \n            \n              Jaffe\n              ES, \n            \n              Burg\n              G, \n            et al\n          . WHO-EORTC classification for cutaneous lymphomas. Blood. 2005;105(10):3768\u20133785."},{"key":"i1543-2165-136-8-876-b06","series-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow\n              SH,","year":"2008","unstructured":"Swerdlow\n              SH, \n            \n              Campo\n              E, \n            \n              Harris\n              NL, \n          \n          et al, eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press;2008. World Health Organization Classification of Tumours; vol 2."},{"issue":"9","key":"i1543-2165-136-8-876-b07","series-title":"Arch Dermatol","first-page":"1144","article-title":"Primary cutaneous diffuse large B-cell lymphoma, leg type: clinicopathologic features and prognostic analysis in 60 cases","volume":"143","author":"Grange\n              F,","year":"2007;","unstructured":"Grange\n              F, \n            \n              Beylot-Barry\n              M, \n            \n              Courville\n              P, \n            et al\n          . Primary cutaneous diffuse large B-cell lymphoma, leg type: clinicopathologic features and prognostic analysis in 60 cases. Arch Dermatol. 2007;143(9):1144\u20131150."},{"issue":"9","key":"i1543-2165-136-8-876-b08","series-title":"J Clin Oncol","first-page":"1376","article-title":"Prognostic factors in primary cutaneous B-cell lymphoma: the Italian Study Group for Cutaneous Lymphomas","volume":"24","author":"Zinzani\n              PL,","year":"2006;","unstructured":"Zinzani\n              PL, \n            \n              Quaglino\n              P, \n            \n              Pimpinelli\n              N, \n            et al\n          . Prognostic factors in primary cutaneous B-cell lymphoma: the Italian Study Group for Cutaneous Lymphomas. J Clin Oncol. 2006;24(9):1376\u20131382."},{"issue":"7","key":"i1543-2165-136-8-876-b09","series-title":"Blood","first-page":"2491","article-title":"Primary cutaneous large B-cell lymphomas: clinicopathologic features, classification, and prognostic factors in a large series of patients","volume":"106","author":"Kodama\n              K,","year":"2005;","unstructured":"Kodama\n              K, \n            \n              Massone\n              C, \n            \n              Chott\n              A, \n            \n              Metze\n              D, \n            \n              Kerl\n              H, \n            \n              Cerroni\n              L. \n          \n          Primary cutaneous large B-cell lymphomas: clinicopathologic features, classification, and prognostic factors in a large series of patients. Blood. 2005;106(7):2491\u20132497."},{"issue":"12","key":"i1543-2165-136-8-876-b10","series-title":"J Clin Oncol","first-page":"1581","article-title":"Reclassification of 300 primary cutaneous B-cell lymphomas according to the new WHO-EORTC classification for cutaneous lymphomas: comparison with previous classifications and identification of prognostic markers","volume":"25","author":"Senff\n              NJ,","year":"2007;","unstructured":"Senff\n              NJ, \n            \n              Hoefnagel\n              JJ, \n            \n              Jansen\n              PM, \n            et al\n          . Reclassification of 300 primary cutaneous B-cell lymphomas according to the new WHO-EORTC classification for cutaneous lymphomas: comparison with previous classifications and identification of prognostic markers. J Clin Oncol. 2007;25(12):1581\u20131587."},{"issue":"5","key":"i1543-2165-136-8-876-b11","series-title":"Blood","first-page":"1600","article-title":"European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas","volume":"112","author":"Senff\n              NJ,","year":"2008;","unstructured":"Senff\n              NJ, \n            \n              Noordijk\n              EM, \n            \n              Kim\n              YH, \n            et al\n          . European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas. Blood. 2008;112(5):1600\u20131609."},{"issue":"4","key":"i1543-2165-136-8-876-b12","series-title":"J Am Acad Dermatol","first-page":"650","article-title":"Primary cutaneous diffuse large B-cell lymphoma, leg type and secondary cutaneous involvement by testicular B-cell lymphoma share identical clinicopathological and immunophenotypical features","volume":"66","author":"Muniesa\n              C,","year":"2012;","unstructured":"Muniesa\n              C, \n            \n              Pujol\n              RM, \n            \n              Estrach\n              MT, \n            et al\n          . Primary cutaneous diffuse large B-cell lymphoma, leg type and secondary cutaneous involvement by testicular B-cell lymphoma share identical clinicopathological and immunophenotypical features. J Am Acad Dermatol. 2012;66(4):650\u2013654."},{"issue":"1","key":"i1543-2165-136-8-876-b13","series-title":"J Dtsch Dermatol Ges","first-page":"12","article-title":"Primary cutaneous B-cell lymphomas [quiz in J Dtsch Dermatol Ges. 2012; 10(1):23]","volume":"10","author":"Kempf\n              W,","year":"2012;","unstructured":"Kempf\n              W, \n            \n              Denisjuk\n              N, \n            \n              Kerl\n              K, \n            \n              Cozzio\n              A, \n            \n              Sander\n              C. \n          \n          Primary cutaneous B-cell lymphomas [quiz in J Dtsch Dermatol Ges. 2012; 10(1):23]. J Dtsch Dermatol Ges. 2012;10(1):12\u201322."},{"issue":"7","key":"i1543-2165-136-8-876-b14","series-title":"Am J Surg Pathol","first-page":"1043","article-title":"IgM expression on paraffin sections distinguishes primary cutaneous large B-cell lymphoma, leg type from primary cutaneous follicle center lymphoma","volume":"34","author":"Koens\n              L,","year":"2010;","unstructured":"Koens\n              L, \n            \n              Vermeer\n              MH, \n            \n              Willemze\n              R, \n            \n              Jansen\n              PM. \n          \n          IgM expression on paraffin sections distinguishes primary cutaneous large B-cell lymphoma, leg type from primary cutaneous follicle center lymphoma. Am J Surg Pathol. 2010;34(7):1043\u20131048."},{"issue":"8","key":"i1543-2165-136-8-876-b15","series-title":"J Clin Oncol","first-page":"2780","article-title":"New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes; Non-Hodgkin's Lymphoma Classification Project","volume":"16","author":"Armitage\n              JO,","year":"1998;","unstructured":"Armitage\n              JO, \n            \n              Weisenburger\n              DD. \n          \n          New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes; Non-Hodgkin's Lymphoma Classification Project. J Clin Oncol. 1998;16(8):2780\u20132795."},{"issue":"1","key":"i1543-2165-136-8-876-b16","series-title":"Am J Surg Pathol","first-page":"16","article-title":"Senile EBV+ B-cell lymphoproliferative disorders: a clinicopathologic study of 22 patients","volume":"27","author":"Oyama\n              T,","year":"2003;","unstructured":"Oyama\n              T, \n            \n              Ichimura\n              K, \n            \n              Suzuki\n              R, \n            et al\n          . Senile EBV+ B-cell lymphoproliferative disorders: a clinicopathologic study of 22 patients. Am J Surg Pathol. 2003;27(1):16\u201326."},{"issue":"17","key":"i1543-2165-136-8-876-b17","series-title":"Clin Cancer Res","first-page":"5124","article-title":"Age-related EBV-associated B-cell lymphoproliferative disorders constitute a distinct clinicopathologic group: a study of 96 patients","volume":"13","author":"Oyama\n              T,","year":"2007;","unstructured":"Oyama\n              T, \n            \n              Yamamoto\n              K, \n            \n              Asano\n              N, \n            et al\n          . Age-related EBV-associated B-cell lymphoproliferative disorders constitute a distinct clinicopathologic group: a study of 96 patients. Clin Cancer Res. 2007;13(17):5124\u20135132."},{"issue":"6","key":"i1543-2165-136-8-876-b18","series-title":"Cancer Sci","first-page":"1085","article-title":"Age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorders: special references to lymphomas surrounding this newly recognized clinicopathologic disease","volume":"99","author":"Shimoyama\n              Y,","year":"2008;","unstructured":"Shimoyama\n              Y, \n            \n              Yamamoto\n              K, \n            \n              Asano\n              N, \n            \n              Oyama\n              T, \n            \n              Kinoshita\n              T, \n            \n              Nakamura\n              S. \n          \n          Age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorders: special references to lymphomas surrounding this newly recognized clinicopathologic disease. Cancer Sci. 2008;99(6):1085\u20131091."},{"issue":"12","key":"i1543-2165-136-8-876-b19","series-title":"Am J Surg Pathol","first-page":"e35","article-title":"Lymphomatoid granulomatosis: insights gained over 4 decades","volume":"34","author":"Katzenstein\n              AL,","year":"2010;","unstructured":"Katzenstein\n              AL, \n            \n              Doxtader\n              E, \n            \n              Narendra\n              S. \n          \n          Lymphomatoid granulomatosis: insights gained over 4 decades. Am J Surg Pathol. 2010;34(12):e35\u2013e48."},{"issue":"9","key":"i1543-2165-136-8-876-b20","series-title":"Am J Surg Pathol","first-page":"1111","article-title":"Cutaneous lymphomatoid granulomatosis: correlation of clinical and biologic features","volume":"25","author":"Beaty\n              MW,","year":"2001;","unstructured":"Beaty\n              MW, \n            \n              Toro\n              J, \n            \n              Sorbara\n              L, \n            et al\n          . Cutaneous lymphomatoid granulomatosis: correlation of clinical and biologic features. Am J Surg Pathol. 2001;25(9):1111\u20131120."},{"issue":"3","key":"i1543-2165-136-8-876-b21","series-title":"Am J Surg Pathol","first-page":"405","article-title":"EBV positive mucocutaneous ulcer\u2014a study of 26 cases associated with various sources of immunosuppression","volume":"34","author":"Dojcinov\n              SD,","year":"2010;","unstructured":"Dojcinov\n              SD, \n            \n              Venkataraman\n              G, \n            \n              Raffeld\n              M, \n            \n              Pittaluga\n              S, \n            \n              Jaffe\n              ES. \n          \n          EBV positive mucocutaneous ulcer\u2014a study of 26 cases associated with various sources of immunosuppression. Am J Surg Pathol. 2010;34(3):405\u2013417."},{"issue":"3, pt 1","key":"i1543-2165-136-8-876-b01","series-title":"J Am Acad Dermatol","first-page":"518","article-title":"Primary cutaneous large cell lymphomas of follicular center cell origin: a clinical follow-up study of nineteen patients","volume":"16","author":"Willemze\n              R,","year":"1987;","unstructured":"Willemze\n              R, \n            \n              Meijer\n              CJ, \n            \n              Sentis\n              HJ, \n            et al\n          . Primary cutaneous large cell lymphomas of follicular center cell origin: a clinical follow-up study of nineteen patients. J Am Acad Dermatol. 1987;16(3, pt 1):518\u2013526."},{"issue":"11","key":"i1543-2165-136-8-876-b02","series-title":"Arch Dermatol","first-page":"1304","article-title":"Primary cutaneous large B-cell lymphomas of the legs: a distinct type of cutaneous B-cell lymphoma with an intermediate prognosis; Dutch Cutaneous Lymphoma Working Group","volume":"132","author":"Vermeer\n              MH,","year":"1996;","unstructured":"Vermeer\n              MH, \n            \n              Geelen\n              FA, \n            \n              van Haselen\n              CW, \n            et al\n          . Primary cutaneous large B-cell lymphomas of the legs: a distinct type of cutaneous B-cell lymphoma with an intermediate prognosis; Dutch Cutaneous Lymphoma Working Group. Arch Dermatol. 1996;132(11):1304\u20131308."},{"issue":"1","key":"i1543-2165-136-8-876-b03","series-title":"Blood","first-page":"354","article-title":"EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer","volume":"90","author":"Willemze\n              R,","year":"1997;","unstructured":"Willemze\n              R, \n            \n              Kerl\n              H, \n            \n              Sterry\n              W, \n            et al\n          . EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer. Blood. 1997;90(1):354\u2013371."},{"issue":"16","key":"i1543-2165-136-8-876-b04","series-title":"J Clin Oncol","first-page":"3602","article-title":"Prognostic factors in primary cutaneous large B-cell lymphomas: a European multicenter study","volume":"19","author":"Grange\n              F,","year":"2001;","unstructured":"Grange\n              F, \n            \n              Bekkenk\n              MW, \n            \n              Wechsler\n              J, \n            et al\n          . Prognostic factors in primary cutaneous large B-cell lymphomas: a European multicenter study. J Clin Oncol. 2001;19(16):3602\u20133610."},{"issue":"10","key":"i1543-2165-136-8-876-b05","series-title":"Blood","first-page":"3768","article-title":"WHO-EORTC classification for cutaneous lymphomas","volume":"105","author":"Willemze\n              R,","year":"2005;","unstructured":"Willemze\n              R, \n            \n              Jaffe\n              ES, \n            \n              Burg\n              G, \n            et al\n          . WHO-EORTC classification for cutaneous lymphomas. Blood. 2005;105(10):3768\u20133785."},{"key":"i1543-2165-136-8-876-b06","series-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow\n              SH,","year":"2008","unstructured":"Swerdlow\n              SH, \n            \n              Campo\n              E, \n            \n              Harris\n              NL, \n          \n          et al, eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press;2008. World Health Organization Classification of Tumours; vol 2."},{"issue":"9","key":"i1543-2165-136-8-876-b07","series-title":"Arch Dermatol","first-page":"1144","article-title":"Primary cutaneous diffuse large B-cell lymphoma, leg type: clinicopathologic features and prognostic analysis in 60 cases","volume":"143","author":"Grange\n              F,","year":"2007;","unstructured":"Grange\n              F, \n            \n              Beylot-Barry\n              M, \n            \n              Courville\n              P, \n            et al\n          . Primary cutaneous diffuse large B-cell lymphoma, leg type: clinicopathologic features and prognostic analysis in 60 cases. Arch Dermatol. 2007;143(9):1144\u20131150."},{"issue":"9","key":"i1543-2165-136-8-876-b08","series-title":"J Clin Oncol","first-page":"1376","article-title":"Prognostic factors in primary cutaneous B-cell lymphoma: the Italian Study Group for Cutaneous Lymphomas","volume":"24","author":"Zinzani\n              PL,","year":"2006;","unstructured":"Zinzani\n              PL, \n            \n              Quaglino\n              P, \n            \n              Pimpinelli\n              N, \n            et al\n          . Prognostic factors in primary cutaneous B-cell lymphoma: the Italian Study Group for Cutaneous Lymphomas. J Clin Oncol. 2006;24(9):1376\u20131382."},{"issue":"7","key":"i1543-2165-136-8-876-b09","series-title":"Blood","first-page":"2491","article-title":"Primary cutaneous large B-cell lymphomas: clinicopathologic features, classification, and prognostic factors in a large series of patients","volume":"106","author":"Kodama\n              K,","year":"2005;","unstructured":"Kodama\n              K, \n            \n              Massone\n              C, \n            \n              Chott\n              A, \n            \n              Metze\n              D, \n            \n              Kerl\n              H, \n            \n              Cerroni\n              L. \n          \n          Primary cutaneous large B-cell lymphomas: clinicopathologic features, classification, and prognostic factors in a large series of patients. Blood. 2005;106(7):2491\u20132497."},{"issue":"12","key":"i1543-2165-136-8-876-b10","series-title":"J Clin Oncol","first-page":"1581","article-title":"Reclassification of 300 primary cutaneous B-cell lymphomas according to the new WHO-EORTC classification for cutaneous lymphomas: comparison with previous classifications and identification of prognostic markers","volume":"25","author":"Senff\n              NJ,","year":"2007;","unstructured":"Senff\n              NJ, \n            \n              Hoefnagel\n              JJ, \n            \n              Jansen\n              PM, \n            et al\n          . Reclassification of 300 primary cutaneous B-cell lymphomas according to the new WHO-EORTC classification for cutaneous lymphomas: comparison with previous classifications and identification of prognostic markers. J Clin Oncol. 2007;25(12):1581\u20131587."},{"issue":"5","key":"i1543-2165-136-8-876-b11","series-title":"Blood","first-page":"1600","article-title":"European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas","volume":"112","author":"Senff\n              NJ,","year":"2008;","unstructured":"Senff\n              NJ, \n            \n              Noordijk\n              EM, \n            \n              Kim\n              YH, \n            et al\n          . European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas. Blood. 2008;112(5):1600\u20131609."},{"issue":"4","key":"i1543-2165-136-8-876-b12","series-title":"J Am Acad Dermatol","first-page":"650","article-title":"Primary cutaneous diffuse large B-cell lymphoma, leg type and secondary cutaneous involvement by testicular B-cell lymphoma share identical clinicopathological and immunophenotypical features","volume":"66","author":"Muniesa\n              C,","year":"2012;","unstructured":"Muniesa\n              C, \n            \n              Pujol\n              RM, \n            \n              Estrach\n              MT, \n            et al\n          . Primary cutaneous diffuse large B-cell lymphoma, leg type and secondary cutaneous involvement by testicular B-cell lymphoma share identical clinicopathological and immunophenotypical features. J Am Acad Dermatol. 2012;66(4):650\u2013654."},{"issue":"1","key":"i1543-2165-136-8-876-b13","series-title":"J Dtsch Dermatol Ges","first-page":"12","article-title":"Primary cutaneous B-cell lymphomas [quiz in J Dtsch Dermatol Ges. 2012; 10(1):23]","volume":"10","author":"Kempf\n              W,","year":"2012;","unstructured":"Kempf\n              W, \n            \n              Denisjuk\n              N, \n            \n              Kerl\n              K, \n            \n              Cozzio\n              A, \n            \n              Sander\n              C. \n          \n          Primary cutaneous B-cell lymphomas [quiz in J Dtsch Dermatol Ges. 2012; 10(1):23]. J Dtsch Dermatol Ges. 2012;10(1):12\u201322."},{"issue":"7","key":"i1543-2165-136-8-876-b14","series-title":"Am J Surg Pathol","first-page":"1043","article-title":"IgM expression on paraffin sections distinguishes primary cutaneous large B-cell lymphoma, leg type from primary cutaneous follicle center lymphoma","volume":"34","author":"Koens\n              L,","year":"2010;","unstructured":"Koens\n              L, \n            \n              Vermeer\n              MH, \n            \n              Willemze\n              R, \n            \n              Jansen\n              PM. \n          \n          IgM expression on paraffin sections distinguishes primary cutaneous large B-cell lymphoma, leg type from primary cutaneous follicle center lymphoma. Am J Surg Pathol. 2010;34(7):1043\u20131048."},{"issue":"8","key":"i1543-2165-136-8-876-b15","series-title":"J Clin Oncol","first-page":"2780","article-title":"New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes; Non-Hodgkin's Lymphoma Classification Project","volume":"16","author":"Armitage\n              JO,","year":"1998;","unstructured":"Armitage\n              JO, \n            \n              Weisenburger\n              DD. \n          \n          New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes; Non-Hodgkin's Lymphoma Classification Project. J Clin Oncol. 1998;16(8):2780\u20132795."},{"issue":"1","key":"i1543-2165-136-8-876-b16","series-title":"Am J Surg Pathol","first-page":"16","article-title":"Senile EBV+ B-cell lymphoproliferative disorders: a clinicopathologic study of 22 patients","volume":"27","author":"Oyama\n              T,","year":"2003;","unstructured":"Oyama\n              T, \n            \n              Ichimura\n              K, \n            \n              Suzuki\n              R, \n            et al\n          . Senile EBV+ B-cell lymphoproliferative disorders: a clinicopathologic study of 22 patients. Am J Surg Pathol. 2003;27(1):16\u201326."},{"issue":"17","key":"i1543-2165-136-8-876-b17","series-title":"Clin Cancer Res","first-page":"5124","article-title":"Age-related EBV-associated B-cell lymphoproliferative disorders constitute a distinct clinicopathologic group: a study of 96 patients","volume":"13","author":"Oyama\n              T,","year":"2007;","unstructured":"Oyama\n              T, \n            \n              Yamamoto\n              K, \n            \n              Asano\n              N, \n            et al\n          . Age-related EBV-associated B-cell lymphoproliferative disorders constitute a distinct clinicopathologic group: a study of 96 patients. Clin Cancer Res. 2007;13(17):5124\u20135132."},{"issue":"6","key":"i1543-2165-136-8-876-b18","series-title":"Cancer Sci","first-page":"1085","article-title":"Age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorders: special references to lymphomas surrounding this newly recognized clinicopathologic disease","volume":"99","author":"Shimoyama\n              Y,","year":"2008;","unstructured":"Shimoyama\n              Y, \n            \n              Yamamoto\n              K, \n            \n              Asano\n              N, \n            \n              Oyama\n              T, \n            \n              Kinoshita\n              T, \n            \n              Nakamura\n              S. \n          \n          Age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorders: special references to lymphomas surrounding this newly recognized clinicopathologic disease. 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