{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T12:46:20Z","timestamp":1770813980730,"version":"3.50.1"},"reference-count":30,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:p>We report on a case of cervical adenocarcinoma in situ in a 42-year-old woman with a history of human papillomavirus infection. Repeat cytology, human papillomavirus testing, and colposcopy failed to identify the lesion. Testing of the cervical cell DNA identified chromosomal abnormalities, prompting a cervical cone biopsy, which identified adenocarcinoma in situ.<\/jats:p>","DOI":"10.5858\/arpa.2012-0499-cr","type":"journal-article","created":{"date-parts":[[2013,11,27]],"date-time":"2013-11-27T17:04:23Z","timestamp":1385571863000},"page":"1829-1831","source":"Crossref","is-referenced-by-count":1,"title":["Cervical Adenocarcinoma Identification by Testing for Chromosomal Abnormalities"],"prefix":"10.5858","volume":"137","author":[{"given":"Janet L.","family":"Dittus","sequence":"first","affiliation":[{"name":"From the Department of Gynecologic Oncology, Tennessee Oncology, Nashville, Tennessee (Dr Dudley); and NeoDiagnostix, Rockville, Maryland (Dr Upender and Mr Endress). Dr Dittus is in private practice, Nashville, Tennessee. Dr. Upender is now the CEO of Naveenum, Potomac, Maryland. Mr Endress is a full-time employee and stockholder of NeoDiagnostix, which provided clinical lab testing during the care of the patient. The other authors have no relevant financial interest in the products or companies..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bunyan S.","family":"Dudley","sequence":"additional","affiliation":[{"name":"From the Department of Gynecologic Oncology, Tennessee Oncology, Nashville, Tennessee (Dr Dudley); and NeoDiagnostix, Rockville, Maryland (Dr Upender and Mr Endress). Dr Dittus is in private practice, Nashville, Tennessee. Dr. Upender is now the CEO of Naveenum, Potomac, Maryland. Mr Endress is a full-time employee and stockholder of NeoDiagnostix, which provided clinical lab testing during the care of the patient. The other authors have no relevant financial interest in the products or companies..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhvi","family":"Upender","sequence":"additional","affiliation":[{"name":"From the Department of Gynecologic Oncology, Tennessee Oncology, Nashville, Tennessee (Dr Dudley); and NeoDiagnostix, Rockville, Maryland (Dr Upender and Mr Endress). Dr Dittus is in private practice, Nashville, Tennessee. Dr. Upender is now the CEO of Naveenum, Potomac, Maryland. Mr Endress is a full-time employee and stockholder of NeoDiagnostix, which provided clinical lab testing during the care of the patient. The other authors have no relevant financial interest in the products or companies..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory A.","family":"Endress","sequence":"additional","affiliation":[{"name":"From the Department of Gynecologic Oncology, Tennessee Oncology, Nashville, Tennessee (Dr Dudley); and NeoDiagnostix, Rockville, Maryland (Dr Upender and Mr Endress). Dr Dittus is in private practice, Nashville, Tennessee. Dr. Upender is now the CEO of Naveenum, Potomac, Maryland. Mr Endress is a full-time employee and stockholder of NeoDiagnostix, which provided clinical lab testing during the care of the patient. The other authors have no relevant financial interest in the products or companies..."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3906","reference":[{"issue":"5","key":"i1543-2165-137-12-1829-b01","series-title":"Am J Pathol","first-page":"1831","article-title":"Detection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal pap smears","volume":"175","author":"Andersson\n              S,","year":"2009","unstructured":"Andersson\n              S,\n\t\t\t\t\t\t\n            \n              Sowjanya\n              P,\n\t\t\t\t\t\t\n            \n              Wangsa\n              D,\n\t\t\t\t\t\t\n            \n              Hjerpe\n              A,\n\t\t\t\t\t\t\n            \n              Johansson\n              B,\n\t\t\t\t\t\t\n            \n              Auer\n              G,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tDetection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal pap smears.\n\t\t\t\t\tAm J Pathol.\n\t\t\t\t\t2009;\n\t\t\t\t\t175(\n\t\t\t\t\t5):\n\t\t\t\t\t1831\u2013\n\t\t\t\t\t1847."},{"issue":"6","key":"i1543-2165-137-12-1829-b02","series-title":"Am J Pathol","first-page":"2637","article-title":"Fluorescence in situ hybridization markers for the prediction of cervical lymph node metastases","volume":"175","author":"Wangsa\n              D,","year":"2009","unstructured":"Wangsa\n              D,\n\t\t\t\t\t\t\n            \n              Heselmeyer-Haddad\n              K,\n\t\t\t\t\t\t\n            \n              Ried\n              P,\n\t\t\t\t\t\t\n            \n              Eriksson\n              E,\n\t\t\t\t\t\t\n            \n              Sch\u00e4ffer\n              AA,\n\t\t\t\t\t\t\n            \n              Morrison\n              LE,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tFluorescence in situ hybridization markers for the prediction of cervical lymph node metastases.\n\t\t\t\t\tAm J Pathol.\n\t\t\t\t\t2009;\n\t\t\t\t\t175(\n\t\t\t\t\t6):\n\t\t\t\t\t2637\u2013\n\t\t\t\t\t2645."},{"issue":"4","key":"i1543-2165-137-12-1829-b03","series-title":"Am J Pathol","first-page":"1229","article-title":"Genomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer","volume":"166","author":"Heselmeyer-Haddad\n              K,","year":"2005","unstructured":"Heselmeyer-Haddad\n              K,\n\t\t\t\t\t\t\n            \n              Sommerfeld\n              K,\n\t\t\t\t\t\t\n            \n              White\n              NM,\n\t\t\t\t\t\t\n            \n              Chaudhri\n              N,\n\t\t\t\t\t\t\n            \n              Morrison\n              LE,\n\t\t\t\t\t\t\n            \n              Palanisamy\n              N,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tGenomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer.\n\t\t\t\t\tAm J Pathol.\n\t\t\t\t\t2005;\n\t\t\t\t\t166(\n\t\t\t\t\t4):\n\t\t\t\t\t1229\u2013\n\t\t\t\t\t1238."},{"issue":"11","key":"i1543-2165-137-12-1829-b04","series-title":"PLoS Genet","article-title":"Gene dosage, expression, and ontology analysis identifies driver genes in the carcinogenesis and chemoradioresistance of cervical cancer","volume":"5","author":"Lando\n              M,","year":"2009","unstructured":"Lando\n              M,\n\t\t\t\t\t\t\n            \n              Holden\n              M,\n\t\t\t\t\t\t\n            \n              Bergersen\n              LC,\n\t\t\t\t\t\t\n            \n              Svendsrud\n              DH,\n\t\t\t\t\t\t\n            \n              Stokke\n              T,\n\t\t\t\t\t\t\n            \n              Sundf\u00f8r\n              K,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tGene dosage, expression, and ontology analysis identifies driver genes in the carcinogenesis and chemoradioresistance of cervical cancer.\n\t\t\t\t\tPLoS Genet.\n\t\t\t\t\t2009;\n\t\t\t\t\t5(\n\t\t\t\t\t11):\n\t\t\t\t\te1000719."},{"issue":"1","key":"i1543-2165-137-12-1829-b05","series-title":"Int J Gynecol Pathol","first-page":"71","article-title":"Utility of p16INK4a, CEA, Ki67, P53 and ER\/PR in the differential diagnosis of benign, premalignant, and malignant glandular lesions of the uterine cervix and their relationship with Silverberg scoring system for endocervical glandular lesions","volume":"26","author":"Liang\n              J,","year":"2007","unstructured":"Liang\n              J,\n\t\t\t\t\t\t\n            \n              Mittal\n              KR,\n\t\t\t\t\t\t\n            \n              Wei\n              JJ,\n\t\t\t\t\t\t\n            \n              Yee\n              H,\n\t\t\t\t\t\t\n            \n              Chiriboga\n              L,\n\t\t\t\t\t\t\n            \n              Shukla\n              P.\n\t\t\t\t\t\t\n          \n          Utility of p16INK4a, CEA, Ki67, P53 and ER\/PR in the differential diagnosis of benign, premalignant, and malignant glandular lesions of the uterine cervix and their relationship with Silverberg scoring system for endocervical glandular lesions.\n\t\t\t\t\tInt J Gynecol Pathol.\n\t\t\t\t\t2007;\n\t\t\t\t\t26(\n\t\t\t\t\t1):\n\t\t\t\t\t71\u2013\n\t\t\t\t\t75."},{"issue":"6","key":"i1543-2165-137-12-1829-b06","series-title":"Obstet Gynecol","first-page":"1419","article-title":"ACOG Practice Bulletin no. 99: management of abnormal cervical cytology and histology","volume":"112","year":"2008","unstructured":"American College of Obstetricians and Gynecologists.\n\t\t\t\t\tACOG Practice Bulletin no. 99: management of abnormal cervical cytology and histology.\n\t\t\t\t\tObstet Gynecol.\n\t\t\t\t\t2008;\n\t\t\t\t\t112(\n\t\t\t\t\t6):\n\t\t\t\t\t1419\u2013\n\t\t\t\t\t1444."},{"issue":"6","key":"i1543-2165-137-12-1829-b07","series-title":"Obstet Gynecol","first-page":"1409","article-title":"ACOG Practice Bulletin no. 109: cervical cytology screening","volume":"114","year":"2009","unstructured":"American College of Obstetricians and Gynecologists.\n\t\t\t\t\tACOG Practice Bulletin no. 109: cervical cytology screening.\n\t\t\t\t\tObstet Gynecol.\n\t\t\t\t\t2009;\n\t\t\t\t\t114(\n\t\t\t\t\t6):\n\t\t\t\t\t1409\u2013\n\t\t\t\t\t1420."},{"issue":"16","key":"i1543-2165-137-12-1829-b08","series-title":"N Engl J Med","first-page":"1589","article-title":"Human papillomavirus and Papanicolaou tests to screen for cervical cancer","volume":"357","author":"Naucler\n              P,","year":"2007","unstructured":"Naucler\n              P,\n\t\t\t\t\t\t\n            \n              Ryd\n              W,\n\t\t\t\t\t\t\n            \n              T\u00f6rnberg\n              S,\n\t\t\t\t\t\t\n            \n              Strand\n              A,\n\t\t\t\t\t\t\n            \n              Wadell\n              G,\n\t\t\t\t\t\t\n            \n              Elfgren\n              K,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tHuman papillomavirus and Papanicolaou tests to screen for cervical cancer.\n\t\t\t\t\tN Engl J Med.\n\t\t\t\t\t2007;\n\t\t\t\t\t357(\n\t\t\t\t\t16):\n\t\t\t\t\t1589\u2013\n\t\t\t\t\t1597."},{"issue":"8","key":"i1543-2165-137-12-1829-b09","series-title":"JAMA","first-page":"813","article-title":"Prevalence of HPV infection among females in the United States","volume":"297","author":"Dunne\n              EF,","year":"2007","unstructured":"Dunne\n              EF,\n\t\t\t\t\t\t\n            \n              Unger\n              ER,\n\t\t\t\t\t\t\n            \n              Sternberg\n              M,\n\t\t\t\t\t\t\n            \n              McQuillan\n              G,\n\t\t\t\t\t\t\n            \n              Swan\n              DC,\n\t\t\t\t\t\t\n            \n              Patel\n              SS,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tPrevalence of HPV infection among females in the United States.\n\t\t\t\t\tJAMA.\n\t\t\t\t\t2007;\n\t\t\t\t\t297(\n\t\t\t\t\t8):\n\t\t\t\t\t813\u2013\n\t\t\t\t\t819."},{"issue":"2","key":"i1543-2165-137-12-1829-b10","series-title":"Obstet Gynecol","first-page":"264","article-title":"Number of cervical biopsies and sensitivity of colposcopy","volume":"108","author":"Gage\n              JC,","year":"2006","unstructured":"Gage\n              JC,\n\t\t\t\t\t\t\n            \n              Hanson\n              VW,\n\t\t\t\t\t\t\n            \n              Abbey\n              K,\n\t\t\t\t\t\t\n            \n              Dippery\n              S,\n\t\t\t\t\t\t\n            \n              Gardner\n              S,\n\t\t\t\t\t\t\n            \n              Kubota\n              J,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tNumber of cervical biopsies and sensitivity of colposcopy.\n\t\t\t\t\tObstet Gynecol.\n\t\t\t\t\t2006;\n\t\t\t\t\t108(\n\t\t\t\t\t2):\n\t\t\t\t\t264\u2013\n\t\t\t\t\t272."},{"issue":"4","key":"i1543-2165-137-12-1829-b11","series-title":"Int J Gynecol Pathol","first-page":"441","article-title":"CIN2 is a much less reproducible and less valid diagnosis than CIN3: results from a histological review of population-based cervical samples","volume":"26","author":"Carreon\n              JD,","year":"2007","unstructured":"Carreon\n              JD,\n\t\t\t\t\t\t\n            \n              Sherman\n              ME,\n\t\t\t\t\t\t\n            \n              Guill\u00e9n\n              D,\n\t\t\t\t\t\t\n            \n              Solomon\n              D,\n\t\t\t\t\t\t\n            \n              Herrero\n              R,\n\t\t\t\t\t\t\n            \n              Jer\u00f3nimo\n              J,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tCIN2 is a much less reproducible and less valid diagnosis than CIN3: results from a histological review of population-based cervical samples.\n\t\t\t\t\tInt J Gynecol Pathol.\n\t\t\t\t\t2007;\n\t\t\t\t\t26(\n\t\t\t\t\t4):\n\t\t\t\t\t441\u2013\n\t\t\t\t\t446."},{"issue":"6","key":"i1543-2165-137-12-1829-b12","series-title":"Am J Obstet Gynecol","first-page":"1383","article-title":"Results of a randomized trial on the management of cytology interpretations of atypical squamous cells of undetermined significance","volume":"188","year":"2003","unstructured":"ASCUS-LSIL Triage Study (ALTS) Group.\n\t\t\t\t\tResults of a randomized trial on the management of cytology interpretations of atypical squamous cells of undetermined significance.\n\t\t\t\t\tAm J Obstet Gynecol.\n\t\t\t\t\t2003;\n\t\t\t\t\t188(\n\t\t\t\t\t6):\n\t\t\t\t\t1383\u2013\n\t\t\t\t\t1392."},{"issue":"6","key":"i1543-2165-137-12-1829-b13","series-title":"Am J Obstet Gynecol","first-page":"1393","article-title":"ASCUS-LSIL Triage Study (ALTS) Group. A randomized trial on the management of low-grade squamous intraepithelial lesion cytology interpretations","volume":"188","author":"Cox\n              JT,","year":"2003","unstructured":"Cox\n              JT,\n\t\t\t\t\t\t\n            \n              Schiffman\n              M,\n\t\t\t\t\t\t\n            \n              Solomon\n              D;\n\t\t\t\t\t\t\n          \n          ASCUS-LSIL Triage Study (ALTS) Group. A randomized trial on the management of low-grade squamous intraepithelial lesion cytology interpretations.\n\t\t\t\t\tAm J Obstet Gynecol.\n\t\t\t\t\t2003;\n\t\t\t\t\t188(\n\t\t\t\t\t6):\n\t\t\t\t\t1393\u2013\n\t\t\t\t\t1400."},{"issue":"6","key":"i1543-2165-137-12-1829-b14","series-title":"Am J Obstet Gynecol","first-page":"1401","article-title":"ASCUS LSIL Triage Study (ALTS) Group. Postcolposcopy management strategies for patients with low-grade squamous intraepithelial lesions or human papillomavirus DNA-positive atypical squamous cells of undetermined significance: two-year prospective study","volume":"188","author":"Guido\n              R,","year":"2003","unstructured":"Guido\n              R,\n\t\t\t\t\t\t\n            \n              Schiffman\n              M,\n\t\t\t\t\t\t\n            \n              Solomon\n              D,\n\t\t\t\t\t\t\n            \n              Burke\n              L;\n\t\t\t\t\t\t\n          \n          ASCUS LSIL Triage Study (ALTS) Group. Postcolposcopy management strategies for patients with low-grade squamous intraepithelial lesions or human papillomavirus DNA-positive atypical squamous cells of undetermined significance: two-year prospective study.\n\t\t\t\t\tAm J Obstet Gynecol.\n\t\t\t\t\t2003;\n\t\t\t\t\t188(\n\t\t\t\t\t6):\n\t\t\t\t\t1401\u2013\n\t\t\t\t\t1405."},{"issue":"6","key":"i1543-2165-137-12-1829-b15","series-title":"Am J Obstet Gynecol","first-page":"1406","article-title":"ASCUS-LSIL Triage Study (ALTS) Group. Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy","volume":"188","author":"Cox\n              JT,","year":"2003","unstructured":"Cox\n              JT,\n\t\t\t\t\t\t\n            \n              Schiffman\n              M,\n\t\t\t\t\t\t\n            \n              Solomon\n              D;\n\t\t\t\t\t\t\n          \n          ASCUS-LSIL Triage Study (ALTS) Group. Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy.\n\t\t\t\t\tAm J Obstet Gynecol.\n\t\t\t\t\t2003;\n\t\t\t\t\t188(\n\t\t\t\t\t6):\n\t\t\t\t\t1406\u2013\n\t\t\t\t\t1412."},{"issue":"5","key":"i1543-2165-137-12-1829-b01","series-title":"Am J Pathol","first-page":"1831","article-title":"Detection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal pap smears","volume":"175","author":"Andersson\n              S,","year":"2009","unstructured":"Andersson\n              S,\n\t\t\t\t\t\t\n            \n              Sowjanya\n              P,\n\t\t\t\t\t\t\n            \n              Wangsa\n              D,\n\t\t\t\t\t\t\n            \n              Hjerpe\n              A,\n\t\t\t\t\t\t\n            \n              Johansson\n              B,\n\t\t\t\t\t\t\n            \n              Auer\n              G,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tDetection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal pap smears.\n\t\t\t\t\tAm J Pathol.\n\t\t\t\t\t2009;\n\t\t\t\t\t175(\n\t\t\t\t\t5):\n\t\t\t\t\t1831\u2013\n\t\t\t\t\t1847."},{"issue":"6","key":"i1543-2165-137-12-1829-b02","series-title":"Am J Pathol","first-page":"2637","article-title":"Fluorescence in situ hybridization markers for the prediction of cervical lymph node metastases","volume":"175","author":"Wangsa\n              D,","year":"2009","unstructured":"Wangsa\n              D,\n\t\t\t\t\t\t\n            \n              Heselmeyer-Haddad\n              K,\n\t\t\t\t\t\t\n            \n              Ried\n              P,\n\t\t\t\t\t\t\n            \n              Eriksson\n              E,\n\t\t\t\t\t\t\n            \n              Sch\u00e4ffer\n              AA,\n\t\t\t\t\t\t\n            \n              Morrison\n              LE,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tFluorescence in situ hybridization markers for the prediction of cervical lymph node metastases.\n\t\t\t\t\tAm J Pathol.\n\t\t\t\t\t2009;\n\t\t\t\t\t175(\n\t\t\t\t\t6):\n\t\t\t\t\t2637\u2013\n\t\t\t\t\t2645."},{"issue":"4","key":"i1543-2165-137-12-1829-b03","series-title":"Am J Pathol","first-page":"1229","article-title":"Genomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer","volume":"166","author":"Heselmeyer-Haddad\n              K,","year":"2005","unstructured":"Heselmeyer-Haddad\n              K,\n\t\t\t\t\t\t\n            \n              Sommerfeld\n              K,\n\t\t\t\t\t\t\n            \n              White\n              NM,\n\t\t\t\t\t\t\n            \n              Chaudhri\n              N,\n\t\t\t\t\t\t\n            \n              Morrison\n              LE,\n\t\t\t\t\t\t\n            \n              Palanisamy\n              N,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tGenomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer.\n\t\t\t\t\tAm J Pathol.\n\t\t\t\t\t2005;\n\t\t\t\t\t166(\n\t\t\t\t\t4):\n\t\t\t\t\t1229\u2013\n\t\t\t\t\t1238."},{"issue":"11","key":"i1543-2165-137-12-1829-b04","series-title":"PLoS Genet","article-title":"Gene dosage, expression, and ontology analysis identifies driver genes in the carcinogenesis and chemoradioresistance of cervical cancer","volume":"5","author":"Lando\n              M,","year":"2009","unstructured":"Lando\n              M,\n\t\t\t\t\t\t\n            \n              Holden\n              M,\n\t\t\t\t\t\t\n            \n              Bergersen\n              LC,\n\t\t\t\t\t\t\n            \n              Svendsrud\n              DH,\n\t\t\t\t\t\t\n            \n              Stokke\n              T,\n\t\t\t\t\t\t\n            \n              Sundf\u00f8r\n              K,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tGene dosage, expression, and ontology analysis identifies driver genes in the carcinogenesis and chemoradioresistance of cervical cancer.\n\t\t\t\t\tPLoS Genet.\n\t\t\t\t\t2009;\n\t\t\t\t\t5(\n\t\t\t\t\t11):\n\t\t\t\t\te1000719."},{"issue":"1","key":"i1543-2165-137-12-1829-b05","series-title":"Int J Gynecol Pathol","first-page":"71","article-title":"Utility of p16INK4a, CEA, Ki67, P53 and ER\/PR in the differential diagnosis of benign, premalignant, and malignant glandular lesions of the uterine cervix and their relationship with Silverberg scoring system for endocervical glandular lesions","volume":"26","author":"Liang\n              J,","year":"2007","unstructured":"Liang\n              J,\n\t\t\t\t\t\t\n            \n              Mittal\n              KR,\n\t\t\t\t\t\t\n            \n              Wei\n              JJ,\n\t\t\t\t\t\t\n            \n              Yee\n              H,\n\t\t\t\t\t\t\n            \n              Chiriboga\n              L,\n\t\t\t\t\t\t\n            \n              Shukla\n              P.\n\t\t\t\t\t\t\n          \n          Utility of p16INK4a, CEA, Ki67, P53 and ER\/PR in the differential diagnosis of benign, premalignant, and malignant glandular lesions of the uterine cervix and their relationship with Silverberg scoring system for endocervical glandular lesions.\n\t\t\t\t\tInt J Gynecol Pathol.\n\t\t\t\t\t2007;\n\t\t\t\t\t26(\n\t\t\t\t\t1):\n\t\t\t\t\t71\u2013\n\t\t\t\t\t75."},{"issue":"6","key":"i1543-2165-137-12-1829-b06","series-title":"Obstet Gynecol","first-page":"1419","article-title":"ACOG Practice Bulletin no. 99: management of abnormal cervical cytology and histology","volume":"112","year":"2008","unstructured":"American College of Obstetricians and Gynecologists.\n\t\t\t\t\tACOG Practice Bulletin no. 99: management of abnormal cervical cytology and histology.\n\t\t\t\t\tObstet Gynecol.\n\t\t\t\t\t2008;\n\t\t\t\t\t112(\n\t\t\t\t\t6):\n\t\t\t\t\t1419\u2013\n\t\t\t\t\t1444."},{"issue":"6","key":"i1543-2165-137-12-1829-b07","series-title":"Obstet Gynecol","first-page":"1409","article-title":"ACOG Practice Bulletin no. 109: cervical cytology screening","volume":"114","year":"2009","unstructured":"American College of Obstetricians and Gynecologists.\n\t\t\t\t\tACOG Practice Bulletin no. 109: cervical cytology screening.\n\t\t\t\t\tObstet Gynecol.\n\t\t\t\t\t2009;\n\t\t\t\t\t114(\n\t\t\t\t\t6):\n\t\t\t\t\t1409\u2013\n\t\t\t\t\t1420."},{"issue":"16","key":"i1543-2165-137-12-1829-b08","series-title":"N Engl J Med","first-page":"1589","article-title":"Human papillomavirus and Papanicolaou tests to screen for cervical cancer","volume":"357","author":"Naucler\n              P,","year":"2007","unstructured":"Naucler\n              P,\n\t\t\t\t\t\t\n            \n              Ryd\n              W,\n\t\t\t\t\t\t\n            \n              T\u00f6rnberg\n              S,\n\t\t\t\t\t\t\n            \n              Strand\n              A,\n\t\t\t\t\t\t\n            \n              Wadell\n              G,\n\t\t\t\t\t\t\n            \n              Elfgren\n              K,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tHuman papillomavirus and Papanicolaou tests to screen for cervical cancer.\n\t\t\t\t\tN Engl J Med.\n\t\t\t\t\t2007;\n\t\t\t\t\t357(\n\t\t\t\t\t16):\n\t\t\t\t\t1589\u2013\n\t\t\t\t\t1597."},{"issue":"8","key":"i1543-2165-137-12-1829-b09","series-title":"JAMA","first-page":"813","article-title":"Prevalence of HPV infection among females in the United States","volume":"297","author":"Dunne\n              EF,","year":"2007","unstructured":"Dunne\n              EF,\n\t\t\t\t\t\t\n            \n              Unger\n              ER,\n\t\t\t\t\t\t\n            \n              Sternberg\n              M,\n\t\t\t\t\t\t\n            \n              McQuillan\n              G,\n\t\t\t\t\t\t\n            \n              Swan\n              DC,\n\t\t\t\t\t\t\n            \n              Patel\n              SS,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tPrevalence of HPV infection among females in the United States.\n\t\t\t\t\tJAMA.\n\t\t\t\t\t2007;\n\t\t\t\t\t297(\n\t\t\t\t\t8):\n\t\t\t\t\t813\u2013\n\t\t\t\t\t819."},{"issue":"2","key":"i1543-2165-137-12-1829-b10","series-title":"Obstet Gynecol","first-page":"264","article-title":"Number of cervical biopsies and sensitivity of colposcopy","volume":"108","author":"Gage\n              JC,","year":"2006","unstructured":"Gage\n              JC,\n\t\t\t\t\t\t\n            \n              Hanson\n              VW,\n\t\t\t\t\t\t\n            \n              Abbey\n              K,\n\t\t\t\t\t\t\n            \n              Dippery\n              S,\n\t\t\t\t\t\t\n            \n              Gardner\n              S,\n\t\t\t\t\t\t\n            \n              Kubota\n              J,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tNumber of cervical biopsies and sensitivity of colposcopy.\n\t\t\t\t\tObstet Gynecol.\n\t\t\t\t\t2006;\n\t\t\t\t\t108(\n\t\t\t\t\t2):\n\t\t\t\t\t264\u2013\n\t\t\t\t\t272."},{"issue":"4","key":"i1543-2165-137-12-1829-b11","series-title":"Int J Gynecol Pathol","first-page":"441","article-title":"CIN2 is a much less reproducible and less valid diagnosis than CIN3: results from a histological review of population-based cervical samples","volume":"26","author":"Carreon\n              JD,","year":"2007","unstructured":"Carreon\n              JD,\n\t\t\t\t\t\t\n            \n              Sherman\n              ME,\n\t\t\t\t\t\t\n            \n              Guill\u00e9n\n              D,\n\t\t\t\t\t\t\n            \n              Solomon\n              D,\n\t\t\t\t\t\t\n            \n              Herrero\n              R,\n\t\t\t\t\t\t\n            \n              Jer\u00f3nimo\n              J,\n\t\t\t\t\t\t\n            et al\n          .\n\t\t\t\t\tCIN2 is a much less reproducible and less valid diagnosis than CIN3: results from a histological review of population-based cervical samples.\n\t\t\t\t\tInt J Gynecol Pathol.\n\t\t\t\t\t2007;\n\t\t\t\t\t26(\n\t\t\t\t\t4):\n\t\t\t\t\t441\u2013\n\t\t\t\t\t446."},{"issue":"6","key":"i1543-2165-137-12-1829-b12","series-title":"Am J Obstet Gynecol","first-page":"1383","article-title":"Results of a randomized trial on the management of cytology interpretations of atypical squamous cells of undetermined significance","volume":"188","year":"2003","unstructured":"ASCUS-LSIL Triage Study (ALTS) Group.\n\t\t\t\t\tResults of a randomized trial on the management of cytology interpretations of atypical squamous cells of undetermined significance.\n\t\t\t\t\tAm J Obstet Gynecol.\n\t\t\t\t\t2003;\n\t\t\t\t\t188(\n\t\t\t\t\t6):\n\t\t\t\t\t1383\u2013\n\t\t\t\t\t1392."},{"issue":"6","key":"i1543-2165-137-12-1829-b13","series-title":"Am J Obstet Gynecol","first-page":"1393","article-title":"ASCUS-LSIL Triage Study (ALTS) Group. A randomized trial on the management of low-grade squamous intraepithelial lesion cytology interpretations","volume":"188","author":"Cox\n              JT,","year":"2003","unstructured":"Cox\n              JT,\n\t\t\t\t\t\t\n            \n              Schiffman\n              M,\n\t\t\t\t\t\t\n            \n              Solomon\n              D;\n\t\t\t\t\t\t\n          \n          ASCUS-LSIL Triage Study (ALTS) Group. A randomized trial on the management of low-grade squamous intraepithelial lesion cytology interpretations.\n\t\t\t\t\tAm J Obstet Gynecol.\n\t\t\t\t\t2003;\n\t\t\t\t\t188(\n\t\t\t\t\t6):\n\t\t\t\t\t1393\u2013\n\t\t\t\t\t1400."},{"issue":"6","key":"i1543-2165-137-12-1829-b14","series-title":"Am J Obstet Gynecol","first-page":"1401","article-title":"ASCUS LSIL Triage Study (ALTS) Group. Postcolposcopy management strategies for patients with low-grade squamous intraepithelial lesions or human papillomavirus DNA-positive atypical squamous cells of undetermined significance: two-year prospective study","volume":"188","author":"Guido\n              R,","year":"2003","unstructured":"Guido\n              R,\n\t\t\t\t\t\t\n            \n              Schiffman\n              M,\n\t\t\t\t\t\t\n            \n              Solomon\n              D,\n\t\t\t\t\t\t\n            \n              Burke\n              L;\n\t\t\t\t\t\t\n          \n          ASCUS LSIL Triage Study (ALTS) Group. Postcolposcopy management strategies for patients with low-grade squamous intraepithelial lesions or human papillomavirus DNA-positive atypical squamous cells of undetermined significance: two-year prospective study.\n\t\t\t\t\tAm J Obstet Gynecol.\n\t\t\t\t\t2003;\n\t\t\t\t\t188(\n\t\t\t\t\t6):\n\t\t\t\t\t1401\u2013\n\t\t\t\t\t1405."},{"issue":"6","key":"i1543-2165-137-12-1829-b15","series-title":"Am J Obstet Gynecol","first-page":"1406","article-title":"ASCUS-LSIL Triage Study (ALTS) Group. Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy","volume":"188","author":"Cox\n              JT,","year":"2003","unstructured":"Cox\n              JT,\n\t\t\t\t\t\t\n            \n              Schiffman\n              M,\n\t\t\t\t\t\t\n            \n              Solomon\n              D;\n\t\t\t\t\t\t\n          \n          ASCUS-LSIL Triage Study (ALTS) Group. Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy.\n\t\t\t\t\tAm J Obstet Gynecol.\n\t\t\t\t\t2003;\n\t\t\t\t\t188(\n\t\t\t\t\t6):\n\t\t\t\t\t1406\u2013\n\t\t\t\t\t1412."}],"container-title":["Archives of Pathology and Laboratory Medicine"],"original-title":[],"link":[{"URL":"https:\/\/aplm.kglmeridian.com\/view\/journals\/arpa\/137\/12\/article-p1829.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aplm.kglmeridian.com\/downloadpdf\/journals\/arpa\/137\/12\/article-p1829.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/aplm.kglmeridian.com\/downloadpdf\/journals\/arpa\/137\/12\/article-p1829.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:57:49Z","timestamp":1770771469000},"score":1,"resource":{"primary":{"URL":"https:\/\/aplm.kglmeridian.com\/view\/journals\/arpa\/137\/12\/article-p1829.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":30,"journal-issue":{"issue":"12"},"URL":"https:\/\/doi.org\/10.5858\/arpa.2012-0499-cr","relation":{},"ISSN":["1543-2165","0003-9985"],"issn-type":[{"value":"1543-2165","type":"electronic"},{"value":"0003-9985","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}