{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T10:07:57Z","timestamp":1786615677659,"version":"build-2736575974"},"reference-count":19,"publisher":"Archives of Pathology and Laboratory Medicine","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,1,1]]},"abstract":"<jats:p>Primary cutaneous lymphomas are defined as non-Hodgkin lymphomas that present in the skin with no evidence of extracutaneous disease at the time of diagnosis. Mycosis fungoides is the most common type of primary cutaneous T-cell lymphoma, representing almost 50% of primary cutaneous T-cell lymphomas, and primary cutaneous CD30+ T-cell lymphoproliferative disorders are the second most common group (30%). Transformed mycosis fungoides is usually CD30+ and can involve multiple nodal sites; other primary cutaneous CD30+ T-cell lymphoproliferative disorders can also involve draining regional nodes. Nodal involvement by CD30+ T-cell lymphoproliferative disorders can mimic classical Hodgkin lymphoma, which can aberrantly express T-cell antigens. The aim of this article is to briefly review salient clinical, histologic, immunophenotypic, and molecular features that can be used to distinguish lymph node involvement by CD30+ cutaneous T-cell lymphomas and lymphoproliferative disorders from classical Hodgkin lymphoma, a clinically important differential diagnosis that represents a challenging task for the pathologist.<\/jats:p>","DOI":"10.5858\/arpa.2016-0352-rs","type":"journal-article","created":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T17:06:02Z","timestamp":1513703162000},"page":"139-142","source":"Crossref","is-referenced-by-count":7,"title":["Nodal Involvement by CD30+ Cutaneous Lymphoproliferative Disorders and Its Challenging Differentiation From Classical Hodgkin Lymphoma"],"prefix":"10.5858","volume":"142","author":[{"given":"Lhara Sumarriva","family":"Lezama","sequence":"first","affiliation":[{"name":"From the Department of Pathology, Mount Sinai St Luke's, Icahn School of Medicine at Mount Sinai, New York, New York (Dr Lezama); and the Department of Pathology, Stanford University School of Medicine, Stanford, California (Dr Gratzinger)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dita","family":"Gratzinger","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, Mount Sinai St Luke's, Icahn School of Medicine at Mount Sinai, New York, New York (Dr Lezama); and the Department of Pathology, Stanford University School of Medicine, Stanford, California (Dr Gratzinger)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3906","reference":[{"issue":"suppl 6","key":"2020081219151028700_i1543-2165-142-1-139-b01","doi-asserted-by":"publisher","first-page":"vi149","DOI":"10.1093\/annonc\/mdt242","article-title":"ESMO Guidelines Working Group. 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