{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T12:22:25Z","timestamp":1756902145953,"version":"3.44.0"},"reference-count":13,"publisher":"The Pediatric Pharmacy Association","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>A 2-year-old male with chronic kidney disease with secondary hyperparathyroidism developed hypercalcemia while receiving calcitriol, without achieving a serum parathyroid hormone concentration within the goal range. Cinacalcet 15 mg (1.2 mg\/kg), crushed and administered via gastrostomy tube, was added to the patient\u2019s therapy. This therapy was effective in achieving targeted laboratory parameters in our patient despite instructions in the prescribing information that cinacalcet should always be taken whole.<\/jats:p>","DOI":"10.5863\/1551-6776-19.3.202","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T20:14:17Z","timestamp":1603829657000},"page":"202-205","source":"Crossref","is-referenced-by-count":0,"title":["Cinacalcet Administration by Gastrostomy Tube in a Child Receiving Peritoneal Dialysis"],"prefix":"10.5863","volume":"19","author":[{"given":"Kristen R.","family":"Nichols","sequence":"first","affiliation":[{"name":"1Department of Pharmacy Practice, College of Pharmacy and Health Sciences, Butler University, Indianapolis, Indiana"},{"name":"2Department of Pharmacy, Riley Hospital for Children, Indiana University Health, Indianapolis, Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chad A.","family":"Knoderer","sequence":"additional","affiliation":[{"name":"1Department of Pharmacy Practice, College of Pharmacy and Health Sciences, Butler University, Indianapolis, Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bethanne","family":"Johnston","sequence":"additional","affiliation":[{"name":"3Department of Pediatrics, Section of Pediatric Nephrology, Indiana University School of Medicine, Indianapolis, Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy C.","family":"Wilson","sequence":"additional","affiliation":[{"name":"3Department of Pediatrics, Section of Pediatric Nephrology, Indiana University School of Medicine, Indianapolis, Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3883","reference":[{"key":"i1551-6776-19-3-202-b1","series-title":"Am J Kidney Dis","first-page":"S1","article-title":"KDOQI clinical practice guidelines for bone metabolism and disease in children with chronic kidney disease","volume":"46","year":"2005","unstructured":"National Kidney Foundation. KDOQI clinical practice guidelines for bone metabolism and disease in children with chronic kidney disease. Am J Kidney Dis. 2005;46:S1\u2013S121."},{"issue":"3","key":"i1551-6776-19-3-202-b2","series-title":"Pediatr Nephrol","first-page":"393","article-title":"Are new vitamin D analogues in renal bone disease superior to calcitriol?","volume":"20","year":"2005","unstructured":"Salusky\n              IB.\n            \n          \n          Are new vitamin D analogues in renal bone disease superior to calcitriol?\n          Pediatr Nephrol. 2005;20(3):393\u2013398."},{"issue":"4","key":"i1551-6776-19-3-202-b3","series-title":"Pediatr Nephrol","first-page":"609","article-title":"New therapies: calcimimetics, phosphate binders and vita-min D receptor activators","volume":"25","year":"2010","unstructured":"Cannata-Andia\n              JB\n            , Rodriguez-GarciaM, Roman-GarciaP, et al. New therapies: calcimimetics, phosphate binders and vita-min D receptor activators. Pediatr Nephrol. 2010;25(4):609\u2013616."},{"issue":"6","key":"i1551-6776-19-3-202-b4","series-title":"Am J Kidney Dis","first-page":"814","article-title":"Intravenous paricalcitol for treatment of secondary hyperparathyroidism in children on hemodialysis","volume":"49","year":"2007","unstructured":"Greenbaum\n              LA\n            , BenadorN, GoldsteinSL, et al. Intravenous paricalcitol for treatment of secondary hyperparathyroidism in children on hemodialysis. Am J Kidney Dis. 2007;49(6):814\u2013823."},{"issue":"5","key":"i1551-6776-19-3-202-b5","series-title":"Pediatr Nephrol","first-page":"622","article-title":"Intravenous calcitriol for treatment of hyperparathyroidism in children on hemodialysis","volume":"20","year":"2005","unstructured":"Greenbaum\n              LA\n            , GrendaR, QiuP, et al. Intravenous calcitriol for treatment of hyperparathyroidism in children on hemodialysis. Pediatr Nephrol. 2005;20(5):622\u2013630."},{"year":"April 2011","series-title":"Zemplar (paricalcitol) [package insert]","key":"i1551-6776-19-3-202-b6","unstructured":"Zemplar (paricalcitol) [package insert]. Lake Forest, IL: Hospira Inc; April 2011."},{"year":"February 2011","series-title":"Hectorol (doxercalciferol) [package insert]","key":"i1551-6776-19-3-202-b7","unstructured":"Hectorol (doxercalciferol) [package insert]. Cambridge, MA: Genzyme Corporation; February 2011."},{"issue":"4","key":"i1551-6776-19-3-202-b8","series-title":"Nutrients","first-page":"1336","article-title":"Comparison between calcitriol and calcitriol plus low-dose cinacalcet for the treatment of moderate to severe secondary hyperparathyroidism in chronic dialysis patients","volume":"5","year":"2013","unstructured":"Lee\n              YT\n            , NgHY, KuoCC, et al. Comparison between calcitriol and calcitriol plus low-dose cinacalcet for the treatment of moderate to severe secondary hyperparathyroidism in chronic dialysis patients. Nutrients. 2013;5(4):1336\u20131348."},{"issue":"1","key":"i1551-6776-19-3-202-b9","series-title":"Pediatr Nephrol","first-page":"143","article-title":"Middle-term use of cinacalcet in paediatric dialysis patients","volume":"25","year":"2010","unstructured":"Platt\n              C\n            , InwardC, McGrawM, et al. Middle-term use of cinacalcet in paediatric dialysis patients. Pediatr Nephrol. 2010;25(1):143\u2013148."},{"issue":"10","key":"i1551-6776-19-3-202-b10","series-title":"Pediatr Nephrol","first-page":"1823","article-title":"Cinacalcet for secondary hyperparathyroidism in children with end-stage renal disease","volume":"23","year":"2008","unstructured":"Muscheites\n              J\n            , WiggerM, DruecklerE, et al. Cinacalcet for secondary hyperparathyroidism in children with end-stage renal disease. Pediatr Nephrol. 2008;23(10):1823\u20131829."},{"issue":"10","key":"i1551-6776-19-3-202-b11","series-title":"Pediatr Nephrol","first-page":"1817","article-title":"Cinacalcet is efficacious in pediatric dialysis patients","volume":"23","year":"2008","unstructured":"Silverstein\n              DM\n            , KherKK, MoudgilA, et al. Cinacalcet is efficacious in pediatric dialysis patients. Pediatr Nephrol. 2008;23(10):1817\u20131822."},{"key":"i1551-6776-19-3-202-b12","unstructured":"Sensipar (cinacalcet hydrochloride): drug safety communication\u2014FDA suspends pediatric clinical trials after report of death. US Food and Drug Administration Web site. http:\/\/www.fda.gov\/Safety\/Med-Watch\/SafetyInformation\/SafetyAlertsforHumanMedicalProducts\/ucm341255.htm. February 2011. Accessed August 12, 2013.","article-title":"Sensipar (cinacalcet hydrochloride): drug safety communication\u2014FDA suspends pediatric clinical trials after report of death. US Food and Drug Administration Web site"},{"issue":"10","key":"i1551-6776-19-3-202-b13","series-title":"Pediatr Nephrol","first-page":"1953","article-title":"An open-label study to evaluate a single-dose of cinacalcet in pediatric dialysis subjects","volume":"27","year":"2012","unstructured":"Padhi\n              D\n            , LangmanCB, FathallahS, et al. An open-label study to evaluate a single-dose of cinacalcet in pediatric dialysis subjects. Pediatr Nephrol. 2012;27(10):1953\u20131959."}],"container-title":["The Journal of Pediatric Pharmacology and Therapeutics"],"original-title":[],"link":[{"URL":"https:\/\/jppt.kglmeridian.com\/view\/journals\/jppt\/19\/3\/article-p202.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/jppt\/article-pdf\/19\/3\/202\/1784237\/1551-6776-19_3_202.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jppt.kglmeridian.com\/downloadpdf\/journals\/jppt\/19\/3\/article-p202.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jppt.kglmeridian.com\/downloadpdf\/journals\/jppt\/19\/3\/article-p202.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:42:12Z","timestamp":1747356132000},"score":1,"resource":{"primary":{"URL":"https:\/\/jppt.kglmeridian.com\/view\/journals\/jppt\/19\/3\/article-p202.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":13,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.5863\/1551-6776-19.3.202","relation":{},"ISSN":["1551-6776"],"issn-type":[{"type":"print","value":"1551-6776"}],"subject":[],"published":{"date-parts":[[2014]]}}}