{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:35:59Z","timestamp":1790436959528,"version":"4.1.0"},"reference-count":107,"publisher":"The Pediatric Pharmacy Association","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,1]]},"abstract":"<jats:p>Type B lactic acidosis can occur secondary to several factors, including thiamine deficiency, and is not as common as type A. Recognizing thiamine deficiency\u2013associated lactic acidosis is challenging because serum thiamine concentrations are not routinely obtained, and a thorough and specific history is necessary for clinicians to suspect thiamine deficiency as a root cause. Furthermore, the appropriate dose and duration of thiamine treatment are not well defined. Untreated thiamine deficiency\u2013associated lactic acidosis can lead to critical illness requiring lifesaving extracorporeal therapies. Additionally, if thiamine and glucose are not administered in an appropriate sequence, Wernicke encephalopathy or Korsakoff syndrome may occur. This review aims to summarize therapeutic treatment for thiamine deficiency\u2013associated lactic acidosis, based on case reports\/series and nutritional guidance. After a literature search of the PubMed database, 63 citations met inclusion criteria, of which 21 involved pediatric patients and are the focus of this review. \u00adCitations describe dosing regimens ranging from 25 to 1000 mg of intravenous (IV) thiamine as a single dose, or multiple daily doses for several days. Specific guidance for critically ill adults recommends a thiamine range of 100 mg IV once daily to 400 mg IV twice daily. Although there are no specific recommendations for the pediatric population, given the relative safety of thiamine administration, its low cost, and our review of the literature, treatment with thiamine 100 to 200 mg IV at least once is supported, with ongoing daily doses based on clinical response of the patient, regardless of age.<\/jats:p>","DOI":"10.5863\/1551-6776-28.5.397","type":"journal-article","created":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T21:33:49Z","timestamp":1696368829000},"page":"397-408","source":"Crossref","is-referenced-by-count":5,"title":["An Overview of Type B Lactic Acidosis Due to Thiamine (B1) Deficiency"],"prefix":"10.5863","volume":"28","author":[{"given":"Kaitlyn J.","family":"Agedal","sequence":"first","affiliation":[{"name":"Department of Pharmacy (KJA, KES, JLB), SUNY Upstate University Hospital, Syracuse, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly E.","family":"Steidl","sequence":"additional","affiliation":[{"name":"Department of Pharmacy (KJA, KES, JLB), SUNY Upstate University Hospital, Syracuse, NY"},{"name":"Department of Pediatrics (KES), SUNY Upstate Medical University, Syracuse, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeni L.","family":"Burgess","sequence":"additional","affiliation":[{"name":"Department of Pharmacy (KJA, KES, JLB), SUNY Upstate University Hospital, Syracuse, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3883","published-online":{"date-parts":[[2023,10,3]]},"reference":[{"issue":"(9)","key":"2023111715282780700_i2331-348X-28-5-397-b1","doi-asserted-by":"crossref","first-page":"e165","DOI":"10.1097\/PEC.0000000000001603","article-title":"Lactic acidosis in a critically ill patient","volume":"34","author":"Schuh","year":"2018","journal-title":"Pediatr Emerg Care"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b2","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1097\/MCO.0b013e32834b8911","article-title":"Thiamine supplementation in the critically ill","volume":"14","author":"Manzanares","year":"2011","journal-title":"Curr Opin Clin Nutr Metab Care"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b3","first-page":"100","article-title":"Vitamin B deficiencies in a critically ill autistic child with a restricted diet","volume":"30","author":"Baird","year":"2014","journal-title":"Nutr Clin Pract"},{"issue":"(2)","key":"2023111715282780700_i2331-348X-28-5-397-b4","first-page":"414","article-title":"Lactic acidosis secondary to thiamin deficiency following autologous stem cell transplantation","volume":"36","author":"Derespina","year":"2020","journal-title":"Nutr Clin Pract"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b5","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1111\/j.1442-200X.1992.tb00988.x","article-title":"Cardiac beriberi (shoshin beriberi) caused by excessive intake of isotonic drink","volume":"34","author":"Fujita","year":"1992","journal-title":"Acta Paediatr Jpn"},{"key":"2023111715282780700_i2331-348X-28-5-397-b6","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3389\/fped.2019.00119","article-title":"Shoshin beriberi and severe accidental hypothermia as causes of heart failure in a 6-year-old child: a case report and brief review of literature","volume":"7","author":"Vicinanza","year":"2019","journal-title":"Front Pediatr"},{"issue":"(11)","key":"2023111715282780700_i2331-348X-28-5-397-b7","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1038\/s41430-022-01170-x","article-title":"Critical vitamin deficiencies in autism spectrum disorder: reversible and irreversible outcomes","volume":"76","author":"Chong","year":"2022","journal-title":"Eur J Clin Nutr"},{"issue":"(2)","key":"2023111715282780700_i2331-348X-28-5-397-b8","doi-asserted-by":"crossref","first-page":"e233","DOI":"10.1542\/peds.2004-1255","article-title":"Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula","volume":"115","author":"Fattal-Valevski","year":"2005","journal-title":"Pediatrics"},{"issue":"(11)","key":"2023111715282780700_i2331-348X-28-5-397-b9","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1007\/s00381-009-0942-3","article-title":"Infantile encephalopathy due to vitamin deficiency in industrial countries","volume":"25","author":"Abu-Kishk","year":"2009","journal-title":"Childs Nerv Syst"},{"issue":"(2)","key":"2023111715282780700_i2331-348X-28-5-397-b10","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.nut.2015.08.007","article-title":"Thiamine responsive acute life threatening metabolic acidosis in exclusively breast-fed infants","volume":"32","author":"Qureshi","year":"2016","journal-title":"Nutrition"},{"key":"2023111715282780700_i2331-348X-28-5-397-b11","doi-asserted-by":"crossref","first-page":"111097","DOI":"10.1016\/j.nut.2020.111097","article-title":"Infantile thiamine deficiency: redefining the clinical patterns","volume":"84","author":"Qureshi","year":"2021","journal-title":"Nutrition"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b12","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.4269\/ajtmh.20-0881","article-title":"Case report: fulminant infantile beriberi: a report of six cases","volume":"104","author":"Samprathi","year":"2021","journal-title":"Am J Trop Med Hyg"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b13","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ihj.2016.07.015","article-title":"Shoshin beriberi-thiamine responsive pulmonary hypertension in exclusively breastfed infants: a study from Northern India","volume":"69","author":"Bhat","year":"2017","journal-title":"Indian Heart J"},{"issue":"(8)","key":"2023111715282780700_i2331-348X-28-5-397-b14","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.arcped.2022.08.017","article-title":"Shoshin beriberi and thiamine-responsive right heart failure: a case report in Mayotte recognition and management of infant Shoshin beriberi","volume":"29","author":"Tann\u00e9","year":"2022","journal-title":"Arch Pediatr"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b15","first-page":"e221","article-title":"Type B lactic acidosis secondary to thiamine deficiency in a child with malignancy","volume":"135","author":"Shah","year":"2014","journal-title":"Pediatrics"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b16","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1177\/0148607114568316","article-title":"Thiamine deficiency in a developed country","volume":"40","author":"Salvatori","year":"2016","journal-title":"J Parenter Enteral Nutr"},{"issue":"(5121032)","key":"2023111715282780700_i2331-348X-28-5-397-b17","first-page":"1","article-title":"Thiamine deficiency leading to refractory lactic acidosis in a pediatric patient","volume":"2017","author":"Teagarden","year":"2017","journal-title":"Case Rep Crit Care."},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b18","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s13312-020-1795-9","article-title":"Wernicke encephalopathy and lactic acidosis in thiamine deficiency","volume":"57","author":"Besci","year":"2020","journal-title":"Indian Pediatr"},{"key":"2023111715282780700_i2331-348X-28-5-397-b19","volume-title":"Presented at: Digestive Disease Week","author":"Anderson","year":"2019"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b20","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1177\/0148607186010001102","article-title":"Shoshin beriberi: an unusual complication of prolonged parenteral nutrition","volume":"10","author":"La Selve","year":"1986","journal-title":"JPEN"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b21","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1007\/s12519-010-0022-5","article-title":"Shoshin beriberi mimicking central line sepsis in a child with short bowel syndrome","volume":"6","author":"Greenspon","year":"2010","journal-title":"World J Pediatr"},{"key":"2023111715282780700_i2331-348X-28-5-397-b22","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.ijcard.2016.07.248","article-title":"An unusual case of cardiogenic shock in which thiamine administration led to reversal of lactic acidosis and heart function recovery: Shoshin beriberi in an adolescent","volume":"222","author":"Cottini","year":"2016","journal-title":"Int J Cardiol"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b23","doi-asserted-by":"crossref","first-page":"e13493","DOI":"10.1111\/petr.13493","article-title":"Acute Shoshin beriberi syndrome immediately post-kidney transplant with rapid recovery after thiamine administration","volume":"23","author":"Elias","year":"2019","journal-title":"Pediatr Transplantation"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b24","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1186\/cc10495","article-title":"Severe lactic acidosis reversed by thiamine within 24 hours","volume":"15","author":"Amrein","year":"2011","journal-title":"Crit Care"},{"issue":"(3)","key":"2023111715282780700_i2331-348X-28-5-397-b25","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1161\/01.CIR.58.3.566","article-title":"Fulminant beriberi heart disease with lactic acidosis: presentation of a case with evaluation of left ventricular function and review of pathophysiologic mechanisms","volume":"58","author":"Attas","year":"1978","journal-title":"Circulation"},{"issue":"(2)","key":"2023111715282780700_i2331-348X-28-5-397-b26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.psym.2012.01.010","article-title":"A case of Shoshin beriberi: lessons old and new for the psychiatrist","volume":"54","author":"Brown","year":"2013","journal-title":"Psychosomatics"},{"issue":"(8)","key":"2023111715282780700_i2331-348X-28-5-397-b27","first-page":"481","article-title":"Shoshin beriberi in a patient with human immunodeficiency virus infection","volume":"19","author":"Bruneel","year":"1993","journal-title":"Intensive Care Med"},{"issue":"(8400)","key":"2023111715282780700_i2331-348X-28-5-397-b28","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0140-6736(84)92918-0","article-title":"The severe lactic acidosis of thiamine deficiency: acute pernicious or fulminating beriberi","volume":"324","author":"Campbell","year":"1984","journal-title":"Lancet"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b29","first-page":"31","article-title":"D. Shoshin beri-beri precipitated by intravenous glucose","volume":"4","author":"Corcoran","year":"2002","journal-title":"Crit Care Resusc"},{"issue":"(51)","key":"2023111715282780700_i2331-348X-28-5-397-b30","first-page":"1","article-title":"Shoshin beriberi in critically-ill patients: case series","volume":"14","author":"Dabar","year":"2015","journal-title":"Nutr J"},{"issue":"(8)","key":"2023111715282780700_i2331-348X-28-5-397-b31","first-page":"1214.e5\u20131214","article-title":"Consideration of alternative causes of lactic acidosis: thiamine deficiency in malignancy","volume":"35","author":"Dean","year":"2017","journal-title":"Am J Emerg Med"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b32","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.4103\/1319-2442.248314","article-title":"Vitamin B1 for type b metabolic acidosis: an underrecognized approach","volume":"29","author":"Dejman","year":"2018","journal-title":"Saudi J Kidney Dis Transpl"},{"issue":"(3)","key":"2023111715282780700_i2331-348X-28-5-397-b33","first-page":"227","article-title":"Beriberi cardiomyopathy","volume":"46","author":"Djoenaidi","year":"1992","journal-title":"Eur J Clin Nutr"},{"issue":"(3)","key":"2023111715282780700_i2331-348X-28-5-397-b34","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/BF01757303","article-title":"Two cases of Shoshin beri beri with hemodynamic and plasma catecholamine data","volume":"6","author":"Fond","year":"1980","journal-title":"Intensive Care Med"},{"issue":"(3)","key":"2023111715282780700_i2331-348X-28-5-397-b35","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/S0952-8180(01)00246-X","article-title":"Early recognition of acute cardiovascular beriberi by interpretation of hemodynamics","volume":"13","author":"Gabrielli","year":"2001","journal-title":"J Clin Anesth"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b36","first-page":"40","article-title":"Resurgence of shoshin beriberi during the COVID-19 pandemic","volume":"34","author":"Govind","year":"2023","journal-title":"Cardiovasc J Afr"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b37","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.jdcr.2020.02.031","article-title":"Shoshin beriberi in a patient with oral and cutaneous graft-versus-host disease","volume":"6","author":"Hodgkinson","year":"2020","journal-title":"JAAD Case Rep"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b38","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1536\/ihj.15-033","article-title":"Shoshin beriberi with low cardiac output and hemodynamic deterioration treated dramatically by thiamine administration","volume":"56","author":"Imamura","year":"2015","journal-title":"Int Heart J"},{"issue":"(11)","key":"2023111715282780700_i2331-348X-28-5-397-b39","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1253\/circj.66.1070","article-title":"Shoshin beriberi with vasospastic angina pectoris. possible mechanism of mid-ventricular obstruction","volume":"66","author":"Ito","year":"2002","journal-title":"Circ J"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b40","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0002-9343(71)90211-7","article-title":"Recovery from proved Shoshin beriberi","volume":"50","author":"Jeffrey","year":"1971","journal-title":"Am J Med"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b41","first-page":"e1","article-title":"A case of shoshin beriberi presenting as cardiogenic shock with diffuse ST-segment elevation, which dramatically improved after a single dose of thiamine","volume":"25","author":"Kim","year":"2014","journal-title":"Cardiovasc J Afr"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b42","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1378\/chest.61.5.512","article-title":"Acute pernicious beriberi heart disease","volume":"61","author":"King","year":"1972","journal-title":"Chest"},{"issue":"(7)","key":"2023111715282780700_i2331-348X-28-5-397-b43","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1007\/s00134-005-2648-7","article-title":"A patient with severe lactic acidosis and rapidly evolving multiple organ failure: a case of shoshin beri-beri","volume":"31","author":"Kountchev","year":"2005","journal-title":"Intensive Care Med"},{"key":"2023111715282780700_i2331-348X-28-5-397-b44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/506072","article-title":"Clinical history and colliquative myocytolysis are keys to the diagnosis of Shoshin beriberi","volume":"2014","author":"Kuno","year":"2014","journal-title":"Case Rep Pathol"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b45","doi-asserted-by":"crossref","first-page":"e670","DOI":"10.7861\/clinmed.2021-0550","article-title":"Lessons of the month 1: Shoshin beriberi: a case report of fulminant cardiovascular collapse, intractable hyperlactatemia and deteriorating consciousness","volume":"21","author":"Lim","year":"2021","journal-title":"Clin Med (Lond)"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b46","doi-asserted-by":"crossref","first-page":"e73","DOI":"10.1016\/j.jemermed.2008.03.040","article-title":"Shoshin beriberi mimicking a high-risk non-st-segment elevation acute coronary syndrome with cardiogenic shock: when the arteries are not guilty","volume":"41","author":"Loma-Osorio","year":"2011","journal-title":"J Emerg Med"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b47","first-page":"331","article-title":"Acute cardiovascular beriberi (shoshin-beriberi) [in Spanish]","volume":"62","author":"Lopez-Gaston","year":"2002","journal-title":"Medicina (B Aires)"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b48","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0300-2977(95)00003-8","article-title":"Acute pernicious or fulminating beriberi heart disease a report of 6 patients","volume":"46","author":"ter Maaten","year":"1995","journal-title":"Neth J Med"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b49","first-page":"69","article-title":"B-cell lymphoma, thiamine deficiency, and lactic acidosis","volume":"30","author":"Masood","year":"2017","journal-title":"Proc (Bayl Univ Med Cent)"},{"issue":"(2)","key":"2023111715282780700_i2331-348X-28-5-397-b50","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/17843286.1988.11717918","article-title":"Shoshin beriberi: a fulminant beriberi heart disease","volume":"43","author":"Meulders","year":"1988","journal-title":"Acta Clin Belg"},{"key":"2023111715282780700_i2331-348X-28-5-397-b51","first-page":"1","article-title":"Shoshin beriberi induced by long-term administration of diuretics: a case report","volume":"2014","author":"Misumida","year":"2014","journal-title":"Case Rep Cardiol"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b52","first-page":"69","article-title":"Acute pernicious (sho-shin) beri-beri: a report of three cases","volume":"1","author":"Motherway","year":"1999","journal-title":"Crit Care Resusc"},{"issue":"(3)","key":"2023111715282780700_i2331-348X-28-5-397-b53","first-page":"128","article-title":"Shoshin beriberi in a young man with gambling addiction","volume":"27","author":"Murase","year":"2022","journal-title":"J Cardiol Cases"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b54","first-page":"241","article-title":"Beriberi heart disease in Durban: a retrospective study","volume":"72","author":"Naidoo","year":"1987","journal-title":"S Afr Med J"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b55","first-page":"283","article-title":"Cardiac beriberi: a report of 4 cases","volume":"72","author":"Naidoo","year":"1987","journal-title":"S Afr Med J"},{"issue":"(3)","key":"2023111715282780700_i2331-348X-28-5-397-b56","first-page":"125","article-title":"Clinical diagnosis of cardiac beriberi","volume":"77","author":"Naidoo","year":"1990","journal-title":"S Afr Med J"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b57","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3390\/life13010205","article-title":"Vitamin B1 deficiency and perimyocarditis fulminans: a case study of shoshin syndrome in a woman following an unbalanced dietary pattern followed by a literature review","volume":"13","author":"Rohun","year":"2023","journal-title":"Life \u00ad(Basel)"},{"issue":"(2)","key":"2023111715282780700_i2331-348X-28-5-397-b58","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/j.1445-5994.1981.tb04231.x","article-title":"Shoshin beriberi","volume":"11","author":"Sambrook","year":"1981","journal-title":"Aust N Z J Med"},{"issue":"(11)","key":"2023111715282780700_i2331-348X-28-5-397-b59","first-page":"817","article-title":"Acute pernicious or fulminating beriberi with severe lactic acidosis: a case report","volume":"68","author":"Seedat","year":"1985","journal-title":"S Afr Med J"},{"key":"2023111715282780700_i2331-348X-28-5-397-b60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/5043818","article-title":"Beriberi induced cardiomyopathy requiring salvage venoarterial extracorporeal membrane oxygenation","volume":"2016","author":"Shah","year":"2016","journal-title":"Case Rep Crit Care"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b61","first-page":"195","article-title":"Shoshin syndrome: two case reports representing opposite ends of the same disease spectrum","volume":"53","author":"Shivalkar","year":"1998","journal-title":"Acta Cardiol"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b62","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0736-4679(98)00040-7","article-title":"Severe acidosis and hyperdynamic circulation in a 39-year-old alcoholic","volume":"16","author":"Smith","year":"1998","journal-title":"J Emerg Med"},{"issue":"(7)","key":"2023111715282780700_i2331-348X-28-5-397-b63","first-page":"e16267","article-title":"Treatment of refractory lactic acidosis with thiamine administration in a non-alcoholic patient","volume":"13","author":"Thota","year":"2021","journal-title":"Cureus"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b64","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.5858\/2006-130-e8-AYWWID","article-title":"A 74-year-old woman with increasing dyspnea","volume":"130","author":"Tran","year":"2006","journal-title":"Arch Pathol Lab Med"},{"issue":"(9)","key":"2023111715282780700_i2331-348X-28-5-397-b65","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1253\/circj.CJ-10-0202","article-title":"Reversible pulmonary hypertension, lactic acidosis, and rapidly evolving multiple organ failure as manifestations of Shoshin beriberi","volume":"74","author":"Yamasaki","year":"2010","journal-title":"Circ J"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b66","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/nyas.13919","article-title":"Thiamine deficiency disorders: diagnosis, prevalence, and a roadmap for Global Control Programs","volume":"1430","author":"Whitfield","year":"2018","journal-title":"Ann NY Acad Sci"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b67","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1007\/s00134-009-1420-9","article-title":"Continuous renal replacement therapy amino acid, trace metal and folate clearance in critically ill children","volume":"35","author":"Zappitelli","year":"2009","journal-title":"Intensive Care Med"},{"issue":"(2)","key":"2023111715282780700_i2331-348X-28-5-397-b68","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1093\/ajcn\/80.2.410","article-title":"Copper, selenium, zinc, and thiamine balances during continuous venovenous hemodiafiltration in critically ill patients","volume":"80","author":"Berger","year":"2004","journal-title":"Am J Clin Nutr"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b69","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1002\/ncp.10212","article-title":"Nutritional support during pediatric extracorporeal membrane oxygenation","volume":"33","author":"Farr","year":"2018","journal-title":"Nutr Clin Pract"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b70","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s13054-017-1644-y","article-title":"Medicating patients during extracorporeal membrane oxygenation: the evidence is building","volume":"21","author":"Dzierba","year":"2017","journal-title":"Crit Care"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b71","doi-asserted-by":"crossref","first-page":"19275","DOI":"10.1038\/s41598-020-76299-5","article-title":"Influence of the ECMO circuit on the concentration of nutritional supplements","volume":"10","author":"Lindberg","year":"2020","journal-title":"Sci Rep"},{"key":"2023111715282780700_i2331-348X-28-5-397-b72","unstructured":"Busti\n              AJ\n            ,\nHerringtonJD.\nEvidence-based medicine consult: why alcoholics should receive vitamin B1 (thiamine) by IV before any glucose infusions.\n2015.\nAccessed September 19, 2021. https:\/\/www.ebmconsult.com\/articles\/thiamine-administration-before-iv-glucose-alcoholics"},{"key":"2023111715282780700_i2331-348X-28-5-397-b73","article-title":"Wernicke-Korsakoff syndrome information page","author":"National Institute of Neurologic Disorders and Stroke","year":"2019"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b74","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1177\/0884533612446706","article-title":"A.S.P.E.N. Position Paper: recommendations for changes in commercially available parenteral multivitamin and multi\u2013trace element products","volume":"27","author":"Vanek","year":"2012","journal-title":"Nutr Clin Pract"},{"issue":"(8):673681","key":"2023111715282780700_i2331-348X-28-5-397-b75","article-title":"Infantile thiamine deficiency: new insights into an old disease","volume":"56","author":"Nazir","year":"2019","journal-title":"Indian Pediatr"},{"issue":"(11)","key":"2023111715282780700_i2331-348X-28-5-397-b76","doi-asserted-by":"crossref","first-page":"496","DOI":"10.3345\/kjp.2014.57.11.496","article-title":"Wernicke\u2019s encephalopathy in a child with high dose thiamine therapy","volume":"57","author":"Park","year":"2014","journal-title":"Korean J Pediatr"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b77","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1177\/0148607114565245","article-title":"Thiamin in clinical practice","volume":"39","author":"Frank","year":"2015","journal-title":"JPEN"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b78","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.clnu.2009.04.024","article-title":"ESPEN: ESPEN guidelines on parenteral nutrition: intensive care","volume":"28","author":"Singer","year":"2009","journal-title":"Clin Nutr"},{"key":"2023111715282780700_i2331-348X-28-5-397-b79","article-title":"ASPEN: optimizing patient care during a multivitamin shortage","author":"Cover","year":"2021","journal-title":"Virtual webinar; March 4"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b80","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.japh.2019.12.005","article-title":"Safety of intravenous push thiamine administration at a tertiary academic medical center","volume":"60","author":"McLaughlin","year":"2020","journal-title":"J Am Pharm Assoc"},{"key":"2023111715282780700_i2331-348X-28-5-397-b81","unstructured":"Thiamine.\nLexi-Drugs.\nHudson, OH:\nLexicomp.\nUpdated March 27, 2022. Accessed March 31, 2022. http:\/\/online.lexi.com\/"},{"issue":"(12)","key":"2023111715282780700_i2331-348X-28-5-397-b82","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.3390\/nu4121977","article-title":"Parenteral nutrition additive shortages: the short-term, long-term and potential epigenetic implications in premature and hospitalized infants","volume":"4","author":"Hanson","year":"2012","journal-title":"Nutrients"},{"key":"2023111715282780700_i2331-348X-28-5-397-b83","unstructured":"Labcorp.\n          Vitamin B1, whole blood.\n2021.\nAccessed March 31, 2022. http:\/\/www.labcorp.com\/tests\/121186\/vitamin-b-sub-1-sub-whole-blood"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b84","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/j.clnu.2022.02.015","article-title":"ESPEN micronutrient guideline","volume":"41","author":"Berger","year":"2022","journal-title":"Clin Nutr"},{"issue":"(3)","key":"2023111715282780700_i2331-348X-28-5-397-b85","doi-asserted-by":"crossref","first-page":"e0003581","DOI":"10.1371\/journal.pntd.0003581","article-title":"Beriberi (thiamine deficiency) and high infant mortality in northern Laos","volume":"9","author":"Barennes","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"issue":"(9)","key":"2023111715282780700_i2331-348X-28-5-397-b86","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/j.1651-2227.1992.tb12346.x","article-title":"Shoshin beriberi in an infant of a thiamine-deficient mother","volume":"81","author":"Debuse","year":"1992","journal-title":"Acta Paediatr"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b87","first-page":"328","article-title":"High prevalence of infantile encephalitic beriberi with overlapping features of Leigh\u2019s disease","volume":"54","author":"Rao","year":"2008","journal-title":"J Trop Pediatr"},{"issue":"(10)","key":"2023111715282780700_i2331-348X-28-5-397-b88","first-page":"566","article-title":"Fulminant cardiac beriberi with severe acidosis","volume":"65","author":"Panichewa","year":"1982","journal-title":"J Med Assoc Thai"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b89","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1093\/tropej\/fmp108","article-title":"Cardiac beriberi: often a missed diagnosis","volume":"56","author":"Rao","year":"2010","journal-title":"J Trop Pediatr"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b90","first-page":"1","article-title":"Cardiac beriberi: morphological findings in two fatal cases","volume":"6","author":"Bello","year":"2011","journal-title":"Diagn Pathol"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b91","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/j.1445-5994.1981.tb04635.x","article-title":"Shoshin or acute pernicious beri beri","volume":"11","author":"Blacket","year":"1981","journal-title":"Aust N Z J Med"},{"issue":"(11)","key":"2023111715282780700_i2331-348X-28-5-397-b92","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1002\/clc.4960151113","article-title":"Shoshin beriberi in an AIDS patient with end-stage renal disease","volume":"15","author":"Cage","year":"1992","journal-title":"Clin Cardiol"},{"issue":"(3)","key":"2023111715282780700_i2331-348X-28-5-397-b93","first-page":"43","article-title":"Deaths associated with thiamine-deficient total parenteral nutrition","volume":"38","author":"Centers for Disease Control (CDC)","year":"1989","journal-title":"MMWR"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b94","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/147323000102900106","article-title":"Cardiac beriberi among illegal mainland Chinese immigrants","volume":"29","author":"Chen","year":"2001","journal-title":"J Int Med Res"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b95","first-page":"e7","article-title":"Thiamin deficiency as a cause of reversible cor pulmonale","volume":"91","author":"Coelho","year":"2008","journal-title":"Arq Bras Cardiol"},{"issue":"(8968)","key":"2023111715282780700_i2331-348X-28-5-397-b96","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0140-6736(95)91240-1","article-title":"\u00adIatrogenic fulminant beriberi","volume":"346","author":"Comabella","year":"1995","journal-title":"Lancet"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b97","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1136\/hrt.51.5.581","article-title":"Shoshin beriberi: a rare diagnostic problem","volume":"51","author":"Engbers","year":"1984","journal-title":"Heart"},{"issue":"(1)","key":"2023111715282780700_i2331-348X-28-5-397-b98","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.1542\/peds.101.1.e10","article-title":"Wernicke encephalopathy and beriberi during total parenteral nutrition attributable to multivitamin infusion shortage","volume":"101","author":"Hahn","year":"1998","journal-title":"Pediatrics"},{"issue":"(4)","key":"2023111715282780700_i2331-348X-28-5-397-b99","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1536\/ihj.46.751","article-title":"Histopathological changes of biopsied myocardium in shoshin beriberi","volume":"46","author":"Kawano","year":"2005","journal-title":"Int Heart J"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b100","doi-asserted-by":"crossref","first-page":"578","DOI":"10.2169\/internalmedicine.44.578","article-title":"ST-segment elevation of electrocardiogram in a patient with Shoshin beriberi","volume":"44","author":"Kawano","year":"2005","journal-title":"Intern Med"},{"issue":"(10)","key":"2023111715282780700_i2331-348X-28-5-397-b101","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/BF00311635","article-title":"TPN-induced fulminant beriberi: a report on our experience and a review of the literature","volume":"26","author":"Kitamura","year":"1996","journal-title":"Surg Today"},{"issue":"(11)","key":"2023111715282780700_i2331-348X-28-5-397-b102","first-page":"546","article-title":"Acute pernicious beriberi in a patient receiving parenteral nutrition: a case report","volume":"75","author":"Naidoo","year":"1989","journal-title":"S Afr Med J"},{"issue":"(5)","key":"2023111715282780700_i2331-348X-28-5-397-b103","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1007\/BF00292932","article-title":"Shoshin beriberi: an underdiagnosed condition?","volume":"12","author":"Pang","year":"1986","journal-title":"Intensive Care Med"},{"issue":"(10)","key":"2023111715282780700_i2331-348X-28-5-397-b104","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1016\/S0002-9149(84)91365-1","article-title":"Shoshin beriberi: report of two successfully treated patients with hemodynamic documentation","volume":"53","author":"Pereira","year":"1984","journal-title":"Am J Cardiol"},{"issue":"(9)","key":"2023111715282780700_i2331-348X-28-5-397-b105","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1097\/00007611-198109000-00028","article-title":"Shoshin beriberi with severe metabolic acidosis","volume":"74","author":"Seta","year":"1981","journal-title":"South Med J"},{"issue":"(6)","key":"2023111715282780700_i2331-348X-28-5-397-b106","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1177\/039139888600900616","article-title":"Acute renal failure in fulminating beriberi","volume":"9","author":"Stratta","year":"1986","journal-title":"Int J Artif Organs"},{"issue":"(S82)","key":"2023111715282780700_i2331-348X-28-5-397-b107","first-page":"S66","article-title":"Acute dilated cardiomyopathy in a patient with beriberi and cryoglobulinaemic vasculitis: an unusual potential complication of two rare disorders","volume":"32","author":"Tejedor","year":"2014","journal-title":"Clin Exp Rheumatol"}],"container-title":["The Journal of Pediatric Pharmacology and Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/meridian.allenpress.com\/jppt\/article-pdf\/28\/5\/397\/3290583\/i2331-348x-28-5-397.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/meridian.allenpress.com\/jppt\/article-pdf\/28\/5\/397\/3290583\/i2331-348x-28-5-397.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T18:38:20Z","timestamp":1738780700000},"score":1,"resource":{"primary":{"URL":"https:\/\/jppt.kglmeridian.com\/view\/journals\/jppt\/28\/5\/article-p397.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,1]]},"references-count":107,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,10,3]]},"published-print":{"date-parts":[[2023,10,1]]}},"URL":"https:\/\/doi.org\/10.5863\/1551-6776-28.5.397","relation":{},"ISSN":["2331-348X","1551-6776"],"issn-type":[{"value":"2331-348X","type":"electronic"},{"value":"1551-6776","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10,1]]}}}